
Douglas Feitosa Tomé
@douglasftome
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Joined January 2017
My second PhD project was published! Grateful to all my mentors and collaborators!
Our new study on the temporal evolution of memory engrams is out in Nature Neuroscience! Check out the full paper with @douglasftome, Ying Zhang, Tomomi Aida, Olivia Mosto, Yifeng Lu, Mandy Chen, Sadra Sadeh, @dheerajroy7 and @ClopathLab! https://t.co/vidveutift
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Glad to have joined #EngramsandEnsembles2025 in #Dublin! Not only did I attend great talks and posters on everything #learning and #memory, but I also hung out with many fun fellow scientists!
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Come check out my poster at COSYNE 2025 later tonight: [1-012] Parallel memory generalization and discrimination across brain regions. Looking forward to engaging discussions! #cosyne2025 #cosyne25 - via #Whova event app
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1/6 Surrogate gradients (SGs) are empirically successful at training spiking neural networks (SNNs). But why do they work so well, and what is their theoretical basis? In our new preprint led by @JuliaGygax4, we provide the answers: https://t.co/QkQ4MniGIG
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Come check out our poster at COSYNE 2024 today at 12:30 pm! - via #Whova Event Platform https://t.co/Twa0lN9Oj0
#cosyne2024 #cosyne24
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RatInABox🐀📦- which began accidentally from some old code I had lying around - grew to become a massive toolkit for navigational research. It's immensely gratifying to see it finally published and being used in such a variety of ways across the field. https://t.co/sgYOzkOXVA
elifesciences.org
A new python package standardises and simplifies how spatial behaviour and neural representations are modelled in continuous environments.
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Excited about our long-brewing paper exploring dynamics in multi-regional neural circuits in a delayed movement task. Driven by@esthersselva, @yiliu021, and including Jennifer Colonell, Nuo Li and @ShaulDr and others (the MAP collaboration): https://t.co/TeruxjeOvc (1/7)
cell.com
A sparse neural network, distributed across major brain compartments, produces tightly orchestrated activity patterns underlying decision-making and movement initiation.
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This gets me every time: ChatGPT's explanation of scientific and mathematical concepts in the style of various poetry and song. Here is Einstein's general relativity in the style of Shakespeare. When will we have a theory of this type of generation and what might it look like?
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1/ Today in Science, we train a neural net from scratch through the eyes and ears of one child. The model learns to map words to visual referents, showing how grounded language learning from just one child's perspective is possible with today's AI tools. https://t.co/hPZiiQt6Vv
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The Clopath Lab is 🔥hiring 🔥a PostDoc and a fully-funded PhD student in the field of computational neuroscience 🧠 at Imperial College London. Details for application here
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#Memory engrams are dynamic, and changes in engram composition mediated by inhibitory plasticity are crucial for the emergence of memory selectivity @douglasftome @dheerajroy7 @ClopathLab
https://t.co/bgZFvoWFbP
nature.com
Nature Neuroscience - This paper shows that memory engrams are dynamic: neurons drop in and out as engrams become selective during memory consolidation. Inhibition and inhibitory plasticity are...
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How might complex representations in hippocampus emerge alongside complex behavior? How can we model the learning of "split" state representations? Check out the latest work of @dr_conehed and @ClopathLab, just published in Nature Communications:
nature.com
Nature Communications - How mechanisms of single-cell plasticity lead to task-dependent cognitive maps remains unclear. Here, the authors show that this model of hippocampus shows that cooperation...
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Our new study on the temporal evolution of memory engrams is out in Nature Neuroscience! Check out the full paper with @douglasftome, Ying Zhang, Tomomi Aida, Olivia Mosto, Yifeng Lu, Mandy Chen, Sadra Sadeh, @dheerajroy7 and @ClopathLab! https://t.co/vidveutift
nature.com
Nature Neuroscience - This paper shows that memory engrams are dynamic: neurons drop in and out as engrams become selective during memory consolidation. Inhibition and inhibitory plasticity are...
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Next Thursday @worldwideneuro! With @analog_ashley, @_Matt_Kelley, @patrickmineault Join us here: https://t.co/JW7wXK0gDH
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A recent preprint from the Rajasethupathy lab found a thalamo-cortical circuit critical for systems consolidation that supports key predictions of our previous computational model with @douglasftome and Sadra Sadeh! Computational model: https://t.co/ZXwp8W1PZw
nature.com
Nature Communications - Systems consolidation refers to the reorganization of memory engrams across brain regions. The authors present a biologically-plausible computational model that shows that...
Anteromedial Thalamus Gates the Selection & Stabilization of Long-Term Memories https://t.co/N93O4ll0rk
#biorxiv_neursci
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Dear #neurotwitter, we dropped this onto @biorxiv_neursci for your perusal. It's an unusual piece from my lab & I really, really enjoyed working on it with @chc1987. Here it is: Metabolically spikes serve neuronal energy homeostasis (and protect neurons). https://t.co/muKt2jNPyG
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Metabolically driven action potentials serve neuronal energy homeostasis and protect from reactive oxygen species https://t.co/o8tk9UpGaC
#biorxiv_neursci
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Can we please stop framing mask wearing as something that some of us "DESIRE" to wear on our campuses? This diminishes the very real risk of transmission to children who cannot be vaccinated and to individuals who are immunocompromised or otherwise at high risk. 1/
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Excited to share our @NatureComms paper that aimed to identify memory engrams distributed throughout the brain. 7 years in the making. This one needed a lot of help from so many fantastic authors! https://t.co/3sWWMgUGhK
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Can neurons drop in and out of memory engrams even though training-activated neurons remain necessary and sufficient for recall? We found that memory engrams are dynamic with engram cell turnover being linked to the emergence of memory selectivity.
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