donato
@donatopmancini
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reporter at bloomberg, ex-FT. usual caveats, DMs open. get in touch:
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Amazingly talented colleagues
The US intel, which Bloomberg scooped, was spot on: a major attack from Iran proper, with missiles and drones, fired at Israel. The intel on the attack timing was correct, too -- officials knew it would happen within 48 hours, as
@business
reported Friday. The stories, by
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Scoop: Health secretary Thérèse Coffey has rejected UKHSA advice to procure additional doses of monkeypox vaccine, stoking concern that the UK is ill-prepared for a possible resurgence of the disease. Officials were "in shock". With
@sarahnev
.
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It’s not like we weren’t told that one of the main possible consequences of vaccine inequity would be … this.
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Two long years
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It took 10 years to make HIV drugs available to poorer nations. “By then, millions of people had died,”
@drtedros
tells me. “We can’t afford to reproduce a similar watershed... Those who do not contribute to these efforts are effectively contributing to prolonging the crisis.”
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.
@federicacocco
,
@kadhim
and I try to explain how the fast-spreading novel coronavirus might affect prison populations. It's not looking great:
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💉🚨💊 Work-related news: Starting next month, I'll be the
@FT
's European pharmaceuticals reporter. I'll be working closely with the great
@hannahkuchler
, who's moving back to London, and the excellent
@clivecookson
and
@sarahnev
. Always happy to chat, so do get in touch.
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🗞️ ⚡️ Personal news: Thrilled to have joined the stellar Bloomberg News
@business
team in Rome to cover politics. Today’s my first day, so do send tips and scoops to dmancini17
@bloomberg
.net.
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Scoop: The US government has “leverage” to compel companies to share key technologies to increase global access to coronavirus shots because they were publicly funded, the NIH's Barney Graham—one of the original inventors—tells the FT. w/
@kiranstacey
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FT SCOOP: Gilead's potential coronavirus candidate remdesivir has flopped in its first randomised clinical trial, according to draft documents published accidentally by the World Health Organisation and seen by the Financial Times. With
@hannahkuchler
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Scoop: The Oxford/AstraZeneca Covid vaccine does not appear to offer protection against mild and moderate disease caused by the variant first identified in South Africa, according to a study seen by the Financial Times.
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NEW: The world faces a shortfall of 3bn Covid-19 vaccine shots early next year if richer nations continue to “aggressively” boost adults and open up immunisation to children, hindering campaigns in poorer countries. With
@sdbernard
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I'm finally Covid-free after being locked up for 22 days. Barely any symptoms, if not for loss of smell/taste towards the end, which would've prompted me to get tested had I not known about exposure. 10+ cases in cluster, all OK. Contact tracing still so v important; wear a mask!
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Sibling ties among suspected Barcelona plotters underline trend
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Some v good, extensive reporting in here. But it's absurd+a terrible indictment of geopolitics & vaccine scarcity that a *newspaper* has to come up with a list of potential mRNA makers across the world. Total failure by pharma, govts, intl institutions.
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Omicron offshoot BA.2 possesses 27 mutations not found in BA.1, the original version. While it may be more transmissible, there are no signs that it is causing more severe illness
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Moderna says A, BioNTech says B, Oxford says C.
@doctorsoumya
: “We believe it’s premature to draw any conclusions about the efficacy of vaccines against Omicron ... We need to be patient.”
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Covid passes boosted economies and vaccine uptake, study suggests
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I'm thrilled to say I'll be joining the Financial Times in London as a general corporate reporter next month. Stay tuned for contact details, and get me on donatopm
@protonmail
.com in the interim.
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So it begins: BBC News - Central London in facial recognition trial
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When asked how much money Covax had left, Berkley said “none”.
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The health agency has finally put out its estimate (110,000) of how many are eligible for vaccination in the UK. Current supply should cover short term demand, with fractional dosing helping to offer second shots, too.
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Some news! After nearly two years, tomorrow's my last day at WSJ/DJ. I'm grateful to have worked with generous and talented colleagues all over the world. But I'm excited for what's next...
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🚨 The European Medicines Agency has refused approval of Merck's Covid-19 drug molnupiravir, aka Lagevrio $MRK
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New 🚨💉💸: Pfizer raised the price of its Covid-19 shot by more than a quarter and Moderna by more than a tenth in the latest EU supply contracts, according to documents seen by the FT. With
@hannahkuchler
&
@mehreenkhn
.
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There's been considerable criticism over how supplies were procured (was the number of those deemed eligible too low? Were supplies of the shot, made by one manufacturer, too tight? Likely a combo). But the shortage, as we've reported, was real:
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New: The World Health Organization has dismissed Temo Waqanivalu, a senior official accused of three separate instances of sexual misconduct over five years.
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Vaccine inequality, exhibit n: The number of booster shots rich nations have administered *in the past 3 months* is bigger than the total number of primary vaccine doses given by poor nations in *all of 2021*. With
@jburnmurdoch
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A surge in bacterial infections after countries lifted pandemic restrictions has led to global shortages of antibiotic drugs, highlighting the precarious state of the world's supply chains -- with
@hannahkuchler
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Scoop: The European pharmaceutical industry’s vaccines lobby has pushed the EU for exemptions that would protect its members from lawsuits if there are problems with any new coronavirus vaccines, according to sources and an internal memo seen by the FT. With
@mikepeeljourno
.
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@martinstabe
Global health authorities have warned for *months* that uneven access to jabs could hasten the emergence of troublesome variants. But change is not happening fast enough. In a handy (and unsettling) graphic:
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SCOOP: Oxford university has begun advertising for participants in a trial to deliver the Covid-19 vaccine it jointly developed with AstraZeneca as a nasal spray, according to documents seen by the FT. With
@henryjfoy
.
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News: Drugmaker AbbVie is being taken to court by a public interest group in the Netherlands for allegedly overcharging Dutch citizens for its blockbuster rheumatoid arthritis drug Humira and breaching their human rights
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Scoop: Remdesivir has little effect on Covid-19 mortality, widely anticipated WHO study says. With
@clivecookson
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Obviously the point here is: The global north is going to all get boosted soon (great) but much of the world still misses *a first shot*. A two tier pandemic is good for no one. Global problems do require global solutions
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Graham's remarks come as NYU researchers argue the patent in question (’070) could entitle the US government to as much as $1.8bn this year alone. “Moderna infringes the NIH patent with every dose of vaccine it makes or sells in the US,”
@cmorten2
says.
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Scoop: Countries negotiating a crucial treaty on pandemics at the WHO have so far struggled to agree key points — including the basic definition of what constitutes a pandemic, according to documents seen by the FT.
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The mRNA hub in South Africa was inaugurated today. Here's a big read with
@jamiesmythf
and
@jsphctrl
from last year explaining the huge potential of the project:
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Scoop: Thérèse Coffey, the new health secretary, has told demoralised UK health workers to "be positive" and "avoid Oxford commas" and "policy wonk", according to an email seen by the FT. "Use 'you' and 'we' — it sounds more human."
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New: The World Health Organization has received a third complaint about sexual misconduct against a senior official within its ranks, raising fresh concerns about the adequacy of the UN health body’s reporting channels and processes.
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Will ‘open-source’ vaccines narrow the inequality gap exposed by Covid? Our big read — with
@jamiesmythf
&
@jsphctrl
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Scoop: one of the reasons behind the cancellation is the
vaccine did less well than rivals in a recent UK trial, named Cov-Boost, that explored the efficacy of various potential boosters $VALN
@mroliverbarnes
@pickardje
@labboudles
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Gaya Gamhewage, the official in charge of rooting out sexual misconduct at WHO, tells me: "We have a bloody problem, right? That’s why we are putting so much effort into it.”
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Remdesivir — which the WHO says should not be used because it has little effect on patients — gave Gilead's fourth-quarter sales a *$2bn* boost.
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is this ... Bolsonaro using his state trip to the UK for the Queen's funeral to talk about how much cheaper gas is in Brazil?
É fácil comparar a situação do Brasil com todos os Países do mundo para sabermos se estamos no rumo certo.
O problema é que sequestraram a mídia e deixaram de discutir economia para discutir “palavrão”.
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Big, big news: Pfizer and BioNTech’s Covid-19 vaccine found to be 90% effective — with
@JoeMillerJr
@clivecookson
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I wrote a slightly absurd story about my absurd and wonderful hometown — "It's like a battle between good and evil": Roman authorities hope they have finally vanquished the bootleg centurions who used to swarm tourists at the Colosseum
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Some of the DRC victims said they were forced to undergo abortions, sometimes forcibly “by giving them drugs or even injections”. No senior officials at the WHO have lost their jobs in the wake of the scandal, which took place between 2018 and 2020.
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AFP: Police officers wearing protective face masks ride horses on their way to visit residents who live in remote areas in Altay, farwest China's Xinjiang region, to promote the awareness of the virus. More at the ft's excellent live blog:
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Scoop! The number of specialized doctors with a EU nationality working in the U.K. dropped to an 8-year low this year, FOIA-obtained figures show, down 11% from its peak. In surgery, the decline is of 23%. With the great
@wsj_douglasj
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Mexico has given Cuba's Soberana vaccine an emergency use authorisation
#Abdala
recibe Autorizo de Uso de Emergencia en México. Avanza inserción internacional de las
#VacunasCubanasCovid19
.
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!!!
An honorable mention is awarded to
@FT
for Covid-19 vaccine rollout. Congratulations
@bydavidcrow
,
@hannahkuchler
,
@donatopmancini
and
@davidpilling
!
#SABEWBIB
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“We might be soon headed towards a post-antibiotic era, where a simple wound or a dental infection can be fatal,” said Hatim Sati, a of the WHO task force on antimicrobial resistance. “That is what’s at stake here.” via
@financialtimes
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“The problem is the lawyers, the lawyers,” the official said. “And they don’t have a clue when they come in. The commission’s lawyers deal with them and I only hear them suffering.” >> Vaccine contracts shrouded in secrecy despite massive public funding
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Nearly 16 booster doses per 100 people were administered across the world’s 59 high-income countries — as defined by the World Bank — up to December 15, compared with just under 11 shots per 100 people of any doses in low-income nations. With
@martinstabe
.
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The
@FT
brings you this definitive tick-tock, so don't miss it >> How AstraZeneca’s vaccine was hit by flawed trials, defects and politics — but might still save the world
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SCOOP! The first papal G-7 leaders’ summit is set to see a significant step back in terms of LGBT rights, according to a draft of the final communique seen by Bloomberg. with
@AlbertoNardelli
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History remdesivirs itself
Not what the US gov wants to hear having spent $2B+ on 3m courses of molnupiravir.
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Oxford and AstraZeneca have begun work to produce an Omicron-targeted version of their coronavirus vaccine, joining the ranks of their peers who are studying adapted shots in case they become necessary to tackle the variant. With
@hannahkuchler
.
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New:
@airfinity
predicts that, in a *best-case scenario* in which all vax makers switch production & scale quickly, 6bn Omicron-targeted 2nd gen doses could be produced by ... October 2022, mostly mRNA.
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Excellent news: Evidence indicates that PCR and rapid antigen tests can detect the new Omicron (B.1.1.529) variant of concern, says FIND after a rapid assessment
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Big breaking news: Moderna’s Covid jab shows 94.5% efficacy in clinical trials — with
@SarahNev
and
@hannahkuchler
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Welcome to the whiplash beat, episode 300: Experts back UK age limit for rollout of AstraZeneca jab via
@clivecookson
,
@annasophiegross
and
@hannahkuchler
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Nerissa died in 1986, aged 66, with only hospital staff attending the funeral, while Katherine died in 2014, aged 86. The sisters received no money from the family other than £125 paid to Earlswood hospital, where they lived, each year. Earlswood closed in 1997.
fun royal family fact: queen elizabeth had two severely disabled first cousins who were publicly pronounced dead in 1940 and 1961 respectively, but they both actually lived in a care home with no visits or support from the royal family until their actual deaths in 1986 and 2014
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WHO’s chief scientist urges greater collaboration against dangerous pathogens
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Worth repeating: the monkeypox vaccine shortage is global. It’s not regional and it’s not national. Countries where monkeypox was endemic before this still have no access to doses.
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Sobering from the scientist behind the first lab study on Pfizer-BioNTech vs omicron, which didn’t look at 2 shots + booster, which everyone in the rich world is obsessed with. Repeating: Boosters aren’t widely available. Many nations still don’t have good enough 2 shot coverage
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Temps in Rome reached highs of 41C today. This is the new normal and it's unliveable.
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WHO creates training hub to boost pharmaceutical production in poor countries
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Top global health officials have become increasingly exasperated with the industry’s inability to boost access and clashed with pharmaceutical executives at a WTO meeting last month, according to two people familiar with what was said >>
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Scoop! The document says the period can be extended only if AZ "acting in good faith" considers that the SARS-COV-2 pandemic is not over. $AZN declines to answer specific Qs, says it'll continue to seek expert guidance "as to when we can say that the pandemic is behind us."
AstraZeneca, which has promised not to profit from its Covid-19 vaccine 'during the pandemic', can declare an end to the outbreak as soon as July next year, according to a document seen by the FT
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Gilead's remdesivir could be made for $9 a course, the study adds. $GILD says that doesn't "accurately reflect the true cost of manufacturing ... at scale”. Encouraging—but v early ()—signs drug could work, as
@hannahkuchler
reported
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Plus: an official tells the FT the WHO will soon suspend the drug from its list of pre-qualified treatments, making remdesivir harder to procure for poorer countries through international organisations. In short: it really, really doesn't work, according to the WHO.
Breaking: WHO advises against giving remdesivir to Covid patients - with
@hannahkuchler
$GILD
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Interesting development. See Barney Graham's remarks to us earlier this year here: Vaccine patent gives US ‘leverage’ over manufacturers
🚨BREAKING $MRNA (Moderna) is in a patent dispute with the
@NIH
over the COVID vaccine Moderna and NIH co-developed. Great quotes from
@cmorten2
,
@zainrizvi
,
@AmeetSarpatwari
and yours truly (from
@PrEP4AllNow
).
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It includes this pandemic annals-worthy quote from the CEO of Moderna, comparing its shot to a Louis Vuitton bag, courtesy of
@jamiesmythf
The mRNA hub in South Africa was inaugurated today. Here's a big read with
@jamiesmythf
and
@jsphctrl
from last year explaining the huge potential of the project:
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In May, Trump announced the emergency nod to remdesivir, hailing Gilead as a “great American company” with “the hot thing”. Six months on, Trump is on his way out, shares are down 29%, and remdesivir is being compared to Tamiflu: a wonder drug that wasn’t.
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Breaking: Tedros overrides the panel and declares monkeypox a public health emergency of international concern. "We have an outbreak that has spread around the world rapidly, through new modes of transmission about which we understand too little."
Tedros on Monkeypox: committee on IHR unable to reach a consensus on whether this is a public health emergency of international concern. WHO's assessment is low everywhere except for European region, where risk is high
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New: Peter Ben Embarek, top WHO Covid investigator, fired for sexual misconduct
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Twenty countries spanning four continents have reported record-breaking numbers of Covid-19 cases in the past week, as Omicron continues to spread globally. With
@jburnmurdoch
&
@stef_palma
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Moderna COVID-19 vaccine patent dispute headed to court -U.S. NIH head says
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While you are sleeping, swarms of Unicef logisticians around the world are busy mapping the world’s fridges
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Pfizer has raised sales projections for its coronavirus vaccine to $33.5bn for the full year, an increase of nearly a third compared with previous guidance, after the shot contributed to a *92%* overall sales increase in the second quarter. $PFE
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this is... unnecessary
Hello, I wrote about the EXTREMELY dystopian vibes inside the bubble at the Beijing Olympics. Exhibit A: Hotel bartenders making specialty cocktails in their full PPE gear
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A wake-up call: Avoiding vaccine nationalism is “no longer about a moral, ethical, humanitarian perspective,”
@JeremyFarrar
tells me. “For me this is now a financial and economic one rather than just a health one.”
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.
@jeremyfarrar
called it in February:
It’s not like we weren’t told that one of the main possible consequences of vaccine inequity would be … this.
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