Two of our articles have become law. Yesterday, President Biden signed a bill creating EPA vector expedited review vouchers which we proposed in a 2015 article. In 2007, President Bush signed a bill creating FDA priority review vouchers which we proposed in a 2006 article.

Great insights on DeepSeek from @StuWoo of @WSJ: 1. ChatGPT is an expert who read all the books; DeepSeek is a detective who finds info on demand. 2. DeepSeek has decent chips because Nvidia adapted to Biden admin restrictions by boosting other capabilities—until those were restricted too.

RT @fermatslibrary: In the fall of 1972, President Nixon announced that "the rate of increase of inflation was decreasing". Probably the fi…

If you led a healthcare company, would you: 1️⃣ As a PBM CEO, pass all rebates to employers, 2️⃣ As a drug maker CEO, reward reps for knowledge & service, not sales, or 3️⃣ Invest in a malaria drug to help millions, despite no profit? Andrew Witty did all three at UnitedHealth & GSK. Not directly profitable, but 1 & 2 might ease regulatory pressure. 3 can attract & inspire talent.

Less is often more, according to Shelley Hwang, MD, MBA, of @DukeU. In her latest study in @JAMA_current, she and her coauthors demonstrated that active monitoring may offer a safe, less invasive approach for managing low-risk ductal carcinoma in situ (DCIS). Watch the video: Read the article:

The @US_FDA published a great summary of novel drug approvals in 2024:

MosquitoMate’s male mosquitoes use Wolbachia bacteria to reduce Aedes aegypti populations by >95%, offering a species-specific solution against dengue, Zika, and yellow fever—without chemicals or genetic modification. 🦟

The GLP-1 miracle drugs provide large cost offsets for Body Mass Index (BMI) > 40 (for example, 5'6" and 250 lbs). For BMI = 30, average cost offsets are negligible. Cost-effectiveness depends on the psychic value of being slim & health benefits beyond weight loss. My take on @cawley_john’s great talk @DukeU!

A study on digital expert advice by @KateBundorf, @MariaAPolyakova, and @mtaiseale revealed surprising insights relevant to AI: 1. The tool increased, rather than saved, time. 2. High-skill users benefited more because low-skill users didn't use it. This highlights how AI's impact depends on selection. It could help low-skill users more, but only if they engage with it. #MatthewEffect

A more nuanced public health message could help rebuild trust, writes @ProfEmilyOster in the @nytimes.

Prof. @cawley_john will give 2 talks at @DukeU on Friday: • 12:45 PM in Fuqua's Leaman classroom: “The New Obesity Drugs: Impacts on Health and Implications for Health Insurance” • 3:00 PM in Social Sciences 111: “The Effects of Taxes on Sugar-Sweetened Beverages”

I'm struggling to reconcile these: • @TheLancet reports a 167% rise in heat-related deaths among 65+ since the 1990s. • @IHME_UW reports that heat and cold exposure are responsible for .1% of deaths and this has *fallen* since the 1990s. Why do they differ? • Is the rise in @TheLancet due to an increase in seniors? • Are deaths from heat offset by lives saved from avoiding cold? • Are other problems in the world growing faster? • Other? Lancet: IHME:

RT @Farzad_MD: 2/ As the press release says 480 ACOs providing care to nearly 11 million people with Medicare saved the gov't $5B dollars…

RT @parker_rog: 🚨 What happens when the gov't cuts prices on medical technologies? New research (w/ @YunanJi) finds a 61% price cut led to…

Pharmacy benefit managers are partnering with drug makers to co-market biosimilars. A previous PBM-pharma tie-up failed. In 1993, Merck acquired Medco, but it didn't last. People didn’t trust a PBM owned by a drug maker.

If your organization is conducting healthcare research with transformative potential, and you're seeking product development funding from the U.S. government, check out the 'Doing Business with ARPA-H Industry Day' on November 13. Learn more here:

Pfizer withdrew its sickle cell drug after deaths from malaria and other diseases. The sickle cell trait protects against malaria. Could the drug be harmful in malaria-endemic areas but beneficial in places like the US? Or does it also significantly reduce protection against other infections?

Welcome to the ACC, Berkeley! At the coin flip when Berkeley plays UNC (in football in 2025?), I hope the loudspeaker blasts the Jo Dee Messina song “Heads Carolina, Tails California”