I am sad
@SuPriyoBabul
, who was a minister in Modi govt., now joins TMC. It is hard to believe how one can change ideology to a 180 degree turn so easily and rapidly. May be people like
@SuPriyoBabul
take politics as profession but not ideology.
Our labs research on CoVID begins today in earnest With my coleagues Dr
@ARanganathan72
and Dr
@shailjasingh75
. Projects involve fast-tracking of BCG and recombinant BCG against CoVID and also screening of FDA-approved drugs against CoVID. Wish us good luck, Jai Hind!
I am so much overwhelmed by the honour given to me by
@BJP4India
and
@BJP4Bengal
to contest from Purbasthali Uttar. Together we will win and change Bengal forever and for the better!
Thank you
@narendramodi
@AmitShah
@JPNadda
and so many others who have put their faith in me!
Thank you Anand but between you and me I cant tell who is guru and who is shishya!
But one thing I do know is that we both are shishyas of
@TIinExile
!
Receiving 20-30 calls everyday from my constituency, Covid vaccine coupons are being distributed by MLA. BJP workers are not given any, rather passing derogatory comments "Vaccine chahiye to Gobardhan ke pass jaa" or convert to TMC. Please help
@MoHFW_INDIA
@ARanganathan72
Just addressed 30,000 strong crowd in Bardhaman Purba constituency in
@BJP4India
janasabha against Trinamool party's corruption, against cutmoney, against appeasement, against murder of our BJP workers.
A call for poribartan. CHANGE IS COMING!
Spoke to some people there, they are excited. Let's see what Bhopal trial reports next. And no goverment appreciation or acknowledgement needed Anand, I'm just doing my job. कर्मण्येवाधिकारस्ते मा फलेषु कदाचन!
Thanks Anand. But what the point is in congratulations. Many lives of elderly could have been saved. My PM
@narendramodi
has advisors who hate him and laugh at him. The establishment is still from UPA. Why shuld I worry anymore. Whats the point of doing any science.
@ARanganathan72
Never mind Anand. Maybe people are right...I need to hate Modi to get acceptance frm Indian scientific agency, need to organize signaturee campaigns against him like current advisors have. But I wont. I love India and
@narendramodi
.
We know what you are saying. Don't interfere in matters you know nothing. Dont undermine Indian experts using uninformed statements made by those who did signature campaign against Modi and hate him! Or you know more than DG, ICMR?
This is all we are saying. Of course we will be proud if the vaccine turns out to work effectively. But offering it before Phase3 clinical trials have proven efficacy is a violation of every scientific protocol &unheard of in the world. Jingoism is no substitute for common sense.
I am an immunologist and have worked on T-cells half my life. In this thread I will present a rebuttal that will hopefully encourage more debate.
The idea that herd immunity can be achieved by 10-20% infected/vaccinated people is itself wrong and deeply flawed. 1/n
1/ There is growing evidence that T-cell immunity allows populations to reach herd immunity once only 10-20% are infected with SARS-CoV-2.
This would explain why a highly transmissible virus in densely populated areas peaked at 10-20% infected regardless of lockdowns or masks.
I was saying this since mid March. I wrote to many authorities. Several countries started, but we ignored months. We also published our paper months back. Even my grant proposal was denied. What we gained? , Lost many precious lives.
@ARanganathan72
@NITIAayog
@kvijayraghavan
BCG shots can give relief to breathless Covid patients
Gora saheb is saying it, so it’s a news and great discovery..
Nobody cared when Our duo
@dasgobardhan
@ARanganathan72
said the sand 6 months back, thousands of lives cud hv been saved
Our peer-reviewed paper just published, on the inverse correlation between BCG immunisation and CoVID susceptibility.
Countries with a universal BCG policy show the lowest CoVID mortality; we find that the type of BCG strain also has a major bearing.
I wish I can write a book soon, how we struggled for food. My father was working as daily wager. One meal in a day. Till my 12th class I was working in field. I never had shoes/chappals till my class 10. This what Gandhi-Nehru-Jinnah gave to us.
@ARanganathan72
BCG clinical trial for COVID-19 is being initiated. Our indigenous strain MIP is better than BCG in inducing anti viral immunity in inducing Interferons and T cell responses. We must initiate clinical trial of MIP ASAP.
@ARanganathan72
@drharshvardhan
#BREAKING
Clinical trial results published in Cell show BCG vaccine protects elderly against infections!
Dear
@AmitShah
ji. I tried mi best, ran pillar post, no one heard me, my proposal was rejected. Now my hope is on you, sir. Start BCG vaccination.
When 2 months ago I said Omicron is a potent vaccine, Modi hating virologists and their pet journalists mocked plus ridiculed me. Now when
@BillGates
says *exactly* the same that Omicron has turned out to be best vaccine, he's praised by same people!
@DrJitendraSingh
@PMOIndia
@ARanganathan72
@shekhar_mande
@drharshvardhan
Blocked from entering my own lab for 3rd day. Now protesters put up a semipermanent pandal also.
Feeling so humiliated. In Oct my lab co-discovered how tuberculosis treatment can be shortened by months. Now banned from taking this fundamental discovery further. What's the point.
In collaboration with
@ARanganathan72
group, we successfully reprogrammed BCG efficacy by simply altering self T cells. It has huge implication in developing/improving vaccine formulation. Indeed, it opens up a new vistas of vaccine research.
@DBTIndia
It's shame, they locked doors with chain. I was very sick, and fainting in front of these students, they were just staring at me. Staffs called ambulance. Alas! we work day and night. Agitating may bring down your hostel fees, but disrespecting teachers will bring bright carrier?
Today is that fateful day of 1946, my father and my great uncle witnessed massacre of family members and neighbours, somehow managed to flee from Noakhali. He keeps on remembering his village, I promised to take him to visit there soon.
@ARanganathan72
@Tarunvijay
Lost many of my family members in "Noakhali" riot. My father was only 4 years old, had to flee to India. Life started in India with a job grazing castles.
If you're not a Hindu refugee from East Pakistan/Bangladesh, you'd never understand the deprivation, the dehumanisation and the degradation we faced. My grandmother left me a crumbling document: the refugee certificate that gave her, a widow, and her 5 children refuge in
#India
.
Total nonsense! Has this been written by
@digvijaya_28
? Don't write on things you know nothing about. Leave science to scientists. Stick to wheeling-dealing.
Sending man in space is sexy, but not really a scientific achievement. India’s big tragedy is still doesn’t know the difference between tech & science
My take:
Challenging a long-standing dogma about tuberculosis, we discover how tuberculosis hides inside humans. We then propose, and also successfully try out, novel strategies that we hope will cure the disease.
@ARanganathan72
@shekhar_mande
@drharshvardhan
Must watch. Great points Anand! Like you even I'd like to see Covaxin data but in the interim we have to trust our experts who have seen the data. Thes is Emergency situation.
Moderna was approved by FDA without peer-review publication. But here Modi hatred leading to outrage!
Remembering Dr. Shyama Prasad Mukherjee on his 67th death anniversary. We the Bengalies are enjoying freedom and citizenship of great nation "India" because of him.
@ARanganathan72
@heeraman98
@BJP4Bengal
In my opinion, we should avoid adenovirus based vaccine. It may give you temporary relief from COVID, but in long term it may cause neurological problems.
@ARanganathan72
@AnantBhan
@dgcsirIndia
I agree with Anand, many Indians r already exposed and cured. I believe we the people of Indian subcontinents 've higher baseline immunity because of exposure of various organisms especially Mycobact. Also, we are immunized with BCG. We must follow govt. advisory, but don't panic
Delighted to share results from our four year collaboration with
@shailjasingh75
,
@dasgobardhan
and Ram from BHU, on the discovery of drug-like molecules that modulate host NAD metabolism and combat Tuberculosis & Malaria infection. Report by
@rohanduaTOI
.
What a contrast! The electoral process was completed in 5 states without any incidence. The night of the WB assembly election result day was a horror. I was confined in-home, next 8 days I was only coordinating with CRPF for the safety of BJP workers. Shame on TMC
@ARanganathan72
@swapan55
da is a wonderful host. Had a nice discussion on the core problems in WB. His super sharp brain, ocean of knowledge, nd depth of thinking is so impressing. Man of integrity, few words, and very pleasant personality. Some people say we look alike- are we?
@ARanganathan72
I was one of the few proponents talked about BCG vaccination for COVID. Here is another excellent result from Russia. Everyday I keep thinking, why I could not convince Indian authorities.
@ARanganathan72
Recent observation from my laboratory in collaboration with
@ARanganathan72
. Curcumin, the wonder drug, the active compound of TURMERIC also called "Indian yellow gold" probably solves the ineffectiveness of TB vaccine.
There is a sad state of affair in
#WestBengal
right now. They (
#TMC
) are torturing, humiliating
#BJP
workers in every villages of the State:
@dasgobardhan
, BJP Leader, tells Padmaja Joshi on
@thenewshour
AGENDA.
Biswajit Deb, TMC Spokesperson & Sr. Advocate counters.
@ARanganathan72
Thanks Anand. Although all Indians are immunized with BCG and we possess higher baseline immunity because of exposure to various viruses and Microbes, we don't have a moment to lose. I propose immediate re-vaccination of all Indians with BCG. Cheapest interim option.
@PMOIndia
Our paper on BCG imparting host resistance against COVID mortality made headline news. A report by
@kalyanray30
. cc
@ARanganathan72
@drharshvardhan
@vijai63
The recombinant SARSCoV2-BCG vaccine construct made in my JNU lab will soon be ready for trials. Wish me luck. Jai Hind!
5th day in row I am blocked from entering my own lab. Their is no security. I can't fight alone. Now students put posters also...one says WE ARE SKIPPING OUR LESSON TO TEACH YOU ONE.
Yes, my own students are going to teach their guru a lesson. This is science?!
Wow.....a risky proposition. I would be interested to see the data. As we all know death rate is less than 5%, among 20 patients expected 1 or none to die. How many in placebo group had severe conditions? Is it a blind trial?
With the wonderful team, starting work on novel plug and play platform for rapidly generating pan Covid vaccines. Exciting times ahead! Need your good wishes n blessings .
@ARanganathan72
Recently many reports indicated that patients who recovered can get the disease again. Also protective antibodies are not lasting long. This means virus vectors may not have high hope. DNA and RNA based vaccines also have same risk. We need out of box ideas...
Hey
@TwitterIndia
Unblock Prof
@ARanganathan72
ASAP.
More than politics 'nd other opinion, Anand's scientific contribution is what inspires. His work on directed evolution and ICAMs is seminal and will enter textbooks. We are using his techniques!
#BringBackAnandRanganathan
That is what I was proposing all along. We now have recombinant strains of BCG expressing antigenic proteins of COVID. Trying to manage funds for monkey experiments, which is bit expensive.
@dasgobardhan
Sir, just want to ask, can we develop a CoVID-19 vaccine from current BCG via some modified strain or with some similar MoA? Does it have the potential?
Heartfelt gratitude
@ARanganathan72
@heeraman98
@BharadwajSpeaks
who are the perfect Teachers (T=Truthful, E=Educated, A=Active, C=character, H=Honest, E=Energetic, R=Responsible) immensely disseminated knowledge and positively impacted on society. Deepest respect and gratitude.
It was an excellent discussion with
@ARanganathan72
and
@kushal_mehra
on COVID-19 vaccination status, gap between priming and booster dose, vaccination for youngsters, various vaccine options, and most importantly mix and vaccination.
@drharshvardhan
Uniforms show that you are part of an organization. Wearing it says that we're all in this together. Wearing uniform with pride you are half way there to being respectful, buying into what the organization is all about. Must follow the ethos of an organization.
@ARanganathan72
Trial study confirms my hypothesis that BCG protects against CoVID! "Infection rate in unvaccinated group was 8.6% versus 0 in booster vaccinated group.”
I'm hopeful my recombinant BCG / MI vaccine with SARS spike protein will give even better protection.
Recombinant BCG/MIP has not seen the light because of over enthusiasm on Oxord vaccine.Demyelinating side effect of adenovirus vector is not unusual. BCG base is safe, and r-BCG gives opportunity for harnessing trend and adaptive immunity.
@ARanganathan72
@ARanganathan72
@ShekharGupta
@ThePrintIndia
n/n If you do not remove the article with still misleading headline present,
@ShekharGupta
I am going to charge you, your media house, and your reporter under the SC/ST Act provisions for my mental and physical harassment.
Wondering how many of them discovered/ developed vaccine? Certainly some in these people are expert in signature campaign against my PM Modi. One of them supporting Aryan Invasion Theory too and secretly saying Modi is anti-Muslim. Guess who?! But Modi govt rewarding them.
@ARanganathan72
@BharadwajSpeaks
I do not know who is Guru and who is Sishya, but I "You are the inspiration who made me win with a spirit. It wouldn’t have been possible without you, Happy Guru Purnima!
BCG clinical trial for COVID-19 is being initiated. Our indigenous strain MIP is better than BCG in inducing anti viral immunity in inducing Interferons and T cell responses. We must initiate clinical trial of MIP ASAP.
@ARanganathan72
@drharshvardhan
Such is the situation in my Bengal that even High court has zero confidence in hospitals there & has ordered airlifting of scam accused Partha Chatterjee to Bhubaneswar for medical checkup. Shame on
@AITCofficial
for manipulating doctors.
@ARanganathan72
@amitmalviya
@tathagata2
This is fantastic! Went through the paper just now, meticulous painstaking research with important implications for new paths for drugs against malaria. Proud of you both
@ARanganathan72
and
@shailjasingh75
!
@dasgobardhan
Pleased to share exciting results from
@shailjasingh75
's and my lab, on the discovery of a molecule that inhibits a crucial mechanism employed by the Malaria parasite for propulsion and motility. Report on this Myosin Motor Blocker by
@kalyanray30
.
मुझे नहीं पता कि कौन गुरु है और कौन शिष्य, लेकिन मैं आपके समुद्र ज्ञान का सम्मान करता हूं।
गुरुर्ब्रह्मा गुरुर्विष्णुः गुरुर्देवो महेश्वरः।
गुरुरेव परंब्रह्म तस्मै श्रीगुरवे नमः।।
मेरी ओर से आपको नया साल मुबारक हो।
@ARanganathan72
@heeraman98
I believe Omicron is "a boon in disguise" as it has spread to more than 90 countries but the majority of patients exhibit mild symptoms which are as similar as to a vaccine. Following similar to "Spanish Flu"- a mild third wave is the beginning of end.
Once again my hypothesis is proved. Omicron is rather a nature made vaccine, and it provides better immune response than that of a booster dose. Immunology is like a mathematical formula, it can't go wrong.
@ARanganathan72
This gives us a lesson! COVID infection is not generating memory response. This means viral vectors either live or inactivated may not yield vaccine efficacy. With the same argument, RNA or DNA based strategies may not work either. Demands out of box strategies..
@ARanganathan72
Requesting hon'ble
@mansukhmandviya
@MoHFW_INDIA
for 40K dosages of vaccines and security for an immediate vaccine camp. We cannot despair of humanity, since we ourselves are human beings. Strong people stand up for themselves, but stronger people stand up for others.
@ARanganathan72
@shailjasingh75
I give up, Anand. It's such a sad day. Some crucial experiments now down the drain..So much effort and planning all to waste. And for what? I have always treated my students as my children. But my own children prevented me from entering lab. I love JNU but Feeling helpless.
@ARanganathan72
@ShekharGupta
1/n I was trying to be nice to
@ShekharGupta
and wrote a mail for few clarifications, as is done in Pubpeer, but he choose not to respond. It is unethical to malign somebody using a noble platform, which is otherwise suppose be neutral and truthful to the truth.
@ARanganathan72
Curious about long term efficacy & safety, which were not tested. (i) Adnvirus known to cause neurological disorders; (ii) It's efficacy is ~62%, on the other hand BCG, which safe proven for 100 yrs, alone can provide ~80 protection. Then, why to import a one which not tested.
Great for masks: SARS-CoV2 doesn’t like cotton
On cotton the amount of active virus had decreased by 99.9%, and it was completely undetectable in less than 24 hours. Virus recovered from cotton over time:
As scientists scramble to come up with answers to halt the novel coronavirus in its tracks, which is currently spreading fast and wide, new research is coming in by the day, opening up new possibilities and pointing new directions to look in.
@dasgobardhan
Addressed 20,000 people yesterday in BJP rally in Satgachhia highliting lawlessness corruption appeasement and murder of BJP workers in Bengal.
Dear Didi, your TMC goons are started issuing threats to me. Tell them being an immunologist I'm immune to them! Change WILL come!
The Bacillus Calmette Guerin or BCG vaccine has shown its ability to boost innate immunity. On Saturday, 2nd May, Dr.
@dasgobardhan
will reveal the association of BCG immunization with protection against COVID-19 disease and mortality.
#SangamTalks
#COVID19
#BCGVaccination
Dr Vijay you are right. Enough is ennough now. When such people are doubting out scientists and spreading propaganda I want to ask, shudnt
@PrinSciAdvGoI
@kvijayraghavan
counter his friend Dr Kang publicly? It is his duty as PSA to
@narendramodi
! Please ask him for science sake.
With due respect to Dr Kang (whom I know personally), the fact remains that she had signed petition against Modi government on the issue that has nothing to do with science. So the possibility of her political views overshadowing her thoughts cannot be ruled out.
We will be waiting in cross fingers to see a head-to-head comparison of BCG and O
xford vaccine. A balance between benefit and side effects. Our effort on recombinant BCG continues, which harnesses both innate and adaptive immunity.
@ARanganathan72
2/n If 10% people have protective immunity, how can they protect rest 90%? Statistical analysis shows that when ~ 70% people are immune, the probability of getting the disease in a given community plummets but still is not foolproof.
Dangerous to assume otherwise.
Yes,
@MahuaMoitra
first you ask yourself why ~25 lakh bengalis migrated in hunt for job? You believe me in 2021, your
#cutmoney
party won't get 20 seats. No matter how much you jump like a headless chicken Bengalis understood TMC very well. U have few more months to loot...
@ARanganathan72
@PMOIndia
Also Anand, while our young population may have less risk to CoVID, BCG immunity fades away with age, thus susceptibility may vary in elders. Re-vaccination will induce IFNs, activate innate components, cytotoxic T cells, generate protective T (EM/CM/SM) CD8+ memory
responses.
@ARanganathan72
Anand, it hurts. For these students we work extra hours, make sure they get good papers and best post doc positions. It's eye opening I was fainting, they were just staring. I travelled from US, 22hrs and did not take rest, came to lab for what and for whom? For these students?
On Guru Purnima my pranam to my dear friend and colleague
@ARanganathan72
. You are the guru of universe at least for that 30 seconds "30 more. seconds Navika" when you demolish commies.
The very day, I travelled 22hrs and came to lab to meet students and work on my manuscript. Because of excessive exhaustion, BP went high, and I was fainting. Doors were locked, and these students did not help me. Staffs called ambulance and took me to health centre.
Indeed, BCG is working...encouraging results are coming from various studies. My personal opinion, BCG is far more safer than adenovirus based vaccine..BCG is safe proven for 100 years..
BCG vaccination, revaccination showing very good results against Covid around the world...
Noted JNU scientist Prof
@dasgobardhan
tells ThePrint’s
@abantika77
@swapan55
It is high time for self realisation of WB BJP leaders. We need better discipline, educated people, and stop rat racing for power chair. People did vote for BJP, centre did more than required, it's unfortunate we could not encash all of these in vote box.
1/n OK!! Friends.. Some of you are upset & few others are simply fuming. Petrol price is Rs. 100/litre. Facts are facts, and some more facts are inside the facts. Have you had a chance to think about the facts:
1. within Rs. 100, Rs. 39-42 goes state and Centre gets only Rs. 23.