IsomLab
@danIsomLab
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illuminating dark drug and cancer targets, novel data science for protein structure informatics, molecular and cellular basis of pH sensing, synBio for health
Miami
Joined August 2019
@MayorDaniella, this resilient elderly woman struggling to make it down the stairs because the elevator (visible) and down escalator at Dadeland South are broken. @FixMetroMDT @iheartmiami305
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@MayorDaniella: this morning at Dadeland South. I didn’t take a photo of the disabled man arguing with security because he couldn’t get up the stairs. I am sure there is cc video of that if you want to see it. @FixMetroMDT @iheartmiami305
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RT @SylvesterCancer: The @Pap_Corps continues to make strides toward a world without cancer. Congratulations, Dr. Daniel Isom (@danIsomLab)…
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Well said.
Cryo-EM structure of an activated GPR4–Gs signaling complex
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These mutations mimic protonation (i.e., activation) and, along with abolishing Na+ negative allosteric modulation, were intended to fully activate GPR4, 65, and 68 precisely as they did.
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