UTSWdiabetes
@UTSWdiabetes
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Joined July 2021
Touchstone Diabetes Center group meeting 2/10/25 Link for full presentation
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Touchstone Diabetes Center group meeting 2/3/25 Link for full presentation
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Touchstone Diabetes Center group meeting 1/27/25 Link for full presentation
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Congrats to Shangang Zhao on the publication of the effects of local adiponectin expression in adipocytes on the activation state of hepatic stellate cells via interactions with PPARgamma. Cell Reports 44, 115165, January 28, 2025
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Commentary by Rachel Perry’s group on two recent papers in Cell Metabolism (Roell and colleagues at Lilly as well as Kusminski and colleagues at UTSW) on the role of the GIPR in adipocytes.
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Touchstone Diabetes Center group meeting 1/13/25 Link for full presentation
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Commentary on the recent papers highlighting the role of GIPR signaling in the adipocyte!
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Obese mice whose fat cells were genetically altered to produce an increased amount of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lost more than a third of their body weight through a mechanism that burns energy, UT Southwestern Medical Center researchers report in a new study. Published in Cell Metabolism, the findings highlight the potential of GIPR – a protein thought of as a minor player in a class of popular weight-loss drugs – to have its own starring role in therapies to fight obesity.
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A protein receptor called PAQR4 found within fat cells appears to act as a sensor for ceramides, waxy lipids whose overabundance has been linked to a variety of metabolic disorders and cancers, a study led by UT Southwestern Medical Center researchers suggests. Their findings, published in Nature Metabolism, could eventually lead to drugs that reduce cellular ceramide levels, much like statins reduce cholesterol levels.
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Touchstone Diabetes Center group meeting 1/6/25 Link for full presentation
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Touchstone Diabetes Center group meeting 12/23/24 Link for full presentation
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Touchstone Diabetes Center group meeting 12/16/24 Link for full presentation
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Congratulations to Christine Kusminski and her group for her latest publication on GIPR action in the adipocyte! A remarkable phenotype!! See or
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Touchstone Diabetes Center group meeting 12/2/24 Link for full presentation
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Touchstone Diabetes Center group meeting 11/25/24 Link for full presentation
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Touchstone Diabetes Center group meeting 11/18/24 Link for full presentation
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Touchstone Diabetes Center group meeting 10/28/24 Link for full presentation
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Touchstone Diabetes Center group meeting 10/21/24 Link for full presentation
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Touchstone Diabetes Center group meeting 10/14/24 Link for full presentation
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