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Terrance G Johns Profile
Terrance G Johns

@TerranceGJohns

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Head of Oncogenic Signalling Laboratory, Telethon Kids: working to improve outcomes in brain cancer. Head of Research at Epigenes: understanding human behavior

Perth and Melbourne Australia
Joined August 2018
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@TerranceGJohns
Terrance G Johns
1 month
Calorie restriction enhances brain health and extends lifespan; it may also help alleviate anxiety and depression. Our review explores the science behind this idea and how we might harness it to create new treatments. #calorierestriction #MentalHealth
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frontiersin.org
Anxiety, depression, and substance use disorders are prevalent mental health disorders that have debilitating health outcomes, and current treatment options ...
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@TerranceGJohns
Terrance G Johns
3 months
After 4 years of groundwork, Epigenes has officially launched from our new labs at La Trobe University. Exciting times ahead as we advance new drugs that mimic the mental health benefits of calorie restriction #mentalhealth #calorierestriction #Epigenetics
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@TerranceGJohns
Terrance G Johns
6 months
Please to share my first paper on calorie restriction (intermittent fasting; IF) with new collaborator Thirum Arumugam. We show that the metabolic benefits of IF can be inherited. #calorierestriction #epigenetics #intermittentfasting.
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@TerranceGJohns
Terrance G Johns
7 months
I’ve been thinking about creating a personal website for a while and decided it’s time! It highlights my brain cancer research alongside my behavioral studies. Excited to share new research directions! #epigenetics #braincancer #CalorieRestriction
terrancejohns.com
Explore the groundbreaking work of Professor Terry Johns in the field of Brain Cancer & Epigenetics. Discover his distinguished contributions to medical research, offering new insights into underst...
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@TerranceGJohns
Terrance G Johns
7 months
Me next to the polka dot pumpkin at the Yayoi Kusama exhibition in Melbourne, Australia. The 95 Japanese artist, Google her, she is unique. #YayoiKusama #NGV #Melbourne #Pumpkin
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@TerranceGJohns
Terrance G Johns
8 months
An albino kangaroo at my golf course in Melbourne, Australia. A good example of a rare genetic event (1;100,000)
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@TerranceGJohns
Terrance G Johns
8 months
Our manuscript describing how epigenetics changes the behavior of lemmings and voles is now published. It may provide some interesting insights into how stress impacts human behavior. #lemmings #behavior #epigenetics.
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onlinelibrary.wiley.com
It is 100 years since the first paper described the recurring nature of Arctic population cycles, yet the mechanistic drivers of these are still not well understood. This paper challenges researche...
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@TerranceGJohns
Terrance G Johns
8 months
Our most recent brain cancer paper is out via early publication. Using ion channel drugs to enhance therapies targeting DNA damage repair in adult and pediatric high-grade glioma. #braincancer #ionchannels #HGG #DIPG #DMG
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academic.oup.com
AbstractBackground. Glioblastoma, a lethal high-grade glioma, has not seen improvements in clinical outcomes in nearly 30 years. Ion channels are increasin
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@TerranceGJohns
Terrance G Johns
10 months
Lemmings are arctic animals that have cycles of boom and bust, which includes dramatic changes in behaviour. They can teach us about human societies. Our paper. #lemmings #behaviour #epigenetics.
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authorea.com
It is 100 years since the first paper described the multiannual cycles in Arctic rodents and lagomorphs. The mechanisms driving population cycles in animals like lemmings and voles are complex, often...
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@TerranceGJohns
Terrance G Johns
1 year
We are looking for a behavioural neuroscientist with experience in animal models to work with us in Melbourne. #behaviour #neuroscience.
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seek.com.au
Find your ideal job at SEEK with 0 Epigenes jobs found in Australia. View all our Epigenes vacancies now with new jobs added daily!
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@TerranceGJohns
Terrance G Johns
1 year
I wear 2 hats, my ongoing brain cancer research and a newer one related to behavioural neuroscience. This new endeavour is @EpigenesAust You will find the link to our new webpage. #fasting #stress #MentalHealth.
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@TerranceGJohns
Terrance G Johns
1 year
Thanks to @TessaJ_Academy I can pitch our new therapeutic approach for brain cancer to an expert committee meeting in Lisbon in May to further its clinical development. #DIPG #GBM #braincancer.
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@TerranceGJohns
Terrance G Johns
2 years
Recently returned from AACR conference in brain cancer in Minneapolis. Fantastic to see the advances in metabolism, epigenetics, AI and neuron/cancer cell interaction. Surely, we can develop new effective treatments. #GBM #DIPG #braintumor
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@TerranceGJohns
Terrance G Johns
2 years
Drawing on the perspective of Australian brain cancer experts (@telethonkidsCC @BrainCancerCtr @DrJeffHolst) our paper in the high impact journal @sigtrans_sttt describes exciting new therapeutic strategies for the treatment of brain cancer #GBM
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nature.com
Signal Transduction and Targeted Therapy - From signalling pathways to targeted therapies: unravelling glioblastoma’s secrets and harnessing two decades of progress
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@TerranceGJohns
Terrance G Johns
2 years
Our manuscript published today in "Cell Reports Medicine" highlights how cross-discipline/tumor research can progress discovery. While this work is based on sarcoma, it is also relevant to brain cancer. #sarcoma #braincancer #Immunotherapy .
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cell.com
Rwandamuriye et al. develop a hydrogel to slowly release poly(I:C) in the tumor resection area. The hydrogel prevents tumor recurrence in multiple mouse models and sensitizes tumors to immune...
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@TerranceGJohns
Terrance G Johns
2 years
Our thoughts on the innovations needed to conduct better clinical trials in brain cancer to accelerate outcomes. We are moving in the right direction but need the community to keep working together. #braincancer #HGG
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link.springer.com
Current Oncology Reports - This review identifies challenges and barriers to successful development of drugs in neuro-oncology trials at the preclinical, clinical and translational stages that we...
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@TerranceGJohns
Terrance G Johns
2 years
Excited to present our work at the International DIPG/DMG Symposium in Lexington, Kentucky on May 19th. #DIPG @CureStartsNow #DMG.
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@TerranceGJohns
Terrance G Johns
3 years
Anoctamins (ANOs), a family of ion channels with emerging roles in #HGG and #DIPG. Their interaction with EGFR maybe important in therapeutic response to EGFRi. Our 3rd recent ion channel review discusses ANOs 10.3390/cancers14235932. Our data papers are coming soon! @Dr_Dewd.
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@TerranceGJohns
Terrance G Johns
3 years
Cancer cells interact with neurons in a two-way dance that drives tumorigenicity and neuronal dysfunction @michelle_monje but it’s also an ecosystem involving astrocytes @c_eroglu and microglia @stevens1lab. Challenge, turning this into effective therapies @NeuroOnc.
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@TerranceGJohns
Terrance G Johns
3 years
Exactly 3 years since last O/S trip, Australians were prevented from international travel during Covid. Visiting @michelle_monje lab tomorrow then onto the SNO annual meeting in Tampa, FL @NeuroOnc. #DIPG #HGG #braincancer.
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