Tom Snelling Profile
Tom Snelling

@TWSnelling

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Postdoc with Philip Cohen @mrcppu @dundeeuni with an interest in cell signalling and rare diseases!

Dundee
Joined February 2019
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@TWSnelling
Tom Snelling
5 months
Excited to share our preprint reporting on the discovery of a new ALPK1 variant causing ROSAH syndrome in a family with 7 affected members! We also characterise this variant, showing its constitutive activity in cells #ROSAH #ALPK1 #mrcppu #UoDLifeSciences
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@TWSnelling
Tom Snelling
2 months
RT @TrendsBiochem: Available online - the Review "Diseases caused by altered specificity of a #proteinkinase for its allosteric activators"…
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@TWSnelling
Tom Snelling
3 months
RT @bioprotocolbyte: Quantitative Measurement of the Kinase Activity of Wildtype ALPK1 and Disease-Causing ALPK1 Mutants Using Cell-Free Ra…
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@TWSnelling
Tom Snelling
3 months
RT @NatureBiotech: Multimodal scanning of genetic variants with base and prime editing
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@TWSnelling
Tom Snelling
3 months
RT @iDikic2: How #autophagy influences the regulation of MHC-I class receptors and regulates #immune evasion of #cancer? A new role for an…
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@TWSnelling
Tom Snelling
3 months
RT @MatthewACoelho: Now open – a CRUK-funded PhD clinical research training fellowship in my team at the Wellcome Sanger Institute. https:/…
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@TWSnelling
Tom Snelling
3 months
RT @DrArpan100: JOB ALERT! MND Accelerator Award funded postdoctoral position in my lab @mrcppu is now LIVE. We will use pooled CRISPR scr…
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@TWSnelling
Tom Snelling
4 months
Happy to share two protocols describing how to study #ALPK1 disease-causing variants using cell-based and cell-free kinase assays! They were used in our recent preprint on #ROSAH syndrome. ( #UoDLifeSciences
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@TWSnelling
Tom Snelling
4 months
RT @Garnettlab: Delighted to share our work in @NatureGenet using base editing to map genetic mechanisms of drug resistance. If you're int…
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@TWSnelling
Tom Snelling
5 months
RT @UoDLifeSciences: Congrats to Celest Tay @taycell & Oliwia Mruk @olimruk who received Highly Commended Awards in the Life Science catego…
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@TWSnelling
Tom Snelling
5 months
@kesslet345 Thanks Abbie 😊
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@TWSnelling
Tom Snelling
5 months
@Dr_Ian_Kelsall Thanks Ian, hope you are doing well!
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@TWSnelling
Tom Snelling
7 months
@David_J_Adams Cool story!
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@TWSnelling
Tom Snelling
8 months
RT @mrcppu: Congratulations Elisha and Catriona: Professor Sir Philip Cohen's 50th and 51st PhD students awarded their degress https://t.co…
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@TWSnelling
Tom Snelling
10 months
RT @gpsapkota: An excellent postdoctoral opportunity to join @sapkota_mrcppu to work on WNT signalling and colorectal cancer. We are lookin…
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@TWSnelling
Tom Snelling
11 months
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@TWSnelling
Tom Snelling
11 months
RT @BiochemSoc: Congratulations to @TWSnelling and @OyieJessica for receiving International Sponsored Places to attend the Biomolecular Hor…
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@TWSnelling
Tom Snelling
1 year
RT @sshadan: To restore cellular homeostasis, stress responses should be turned off at the right time and place. A paper @nature shows a ub…
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@TWSnelling
Tom Snelling
1 year
Thrilled to have been awarded the Howard Elder Prize for my work on ALPK1😃. This kinase is activated by bacterial ADP-heptose, but mutations that cause a genetic disease and a rare cancer allow it to also be activated by human metabolites! #ALPK1 @mrcppu @UoDLifeSciences
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@TWSnelling
Tom Snelling
1 year
RT @rbdamgaard: 📢 Are you interested in joining our lab in Copenhagen🇩🇰 as a #postdoc? We are an ambitious and friendly research group 👩‍🔬…
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