@QuoteJung Freud was right about so much that it changed our culture in favor of less repression and presents the most comprehensive view of the human mind. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

The obvious mismatch between the modern sedentary lifestyle and our caveman ancestors which was endlessly physical easily accounts for this and highlights the importance of the evolutionary point of view. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

IL 6 May just be in response to the atrophy seen with depression which can be considered a neuronal involution which responds to the increase in growth factors seen with meds like ketamine. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

@chrisaikenmd Bariatric surgery is well known to interfere with absorption and switching to liquid medication where possibly is often beneficial. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

Yes, this due to the fact that there is a mismatch between our modern lifestyle and that of our evolutionary forebears. Cave people engaged in endless movement and sunlight. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

Some people are able to turn the death instinct against themselves and engage in self destructiveness including enlisting the immune system to attack various parts of the body including the gut and the skin. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

@JDaviesPhD Youth suicides are increasing and all cause mortality for 25 to 45 year olds is surging. Nihilism due to global warming and political discord may be contributors. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

@ItaiYanai Psychiatry remains in the dark ages due to its refusal to consider new ideas including the importance of evolution in mental illness. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

@psycheureka CBD has some dopamine blocking properties so the lower levels may increase psychosis risk. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

@chrisaikenmd It seems to be correlated with the extent of involvement with the histamine receptor which is why we see weight gain with mirtazapine as well. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

@MAstronomers Not a Macdonalds in the place. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

Stigma about mental illness remains rampant since we really don’t understand the illnesses we treat. This is due to orthodox psychiatry refusing to acknowledge the role of evolution in creating these afflictions. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

@kirawontmiss As the greatest sublimation for hostile and aggressive impulses sports takes on a weird intensity as they work to preserve civilization. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

@PhysInHistory Kind of like why they charge so much for those tiny mock tails. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

@PhysInHistory Sigmund Freud and Charles Darwin. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

@QuoteJung Only because they’re usually not interested in you. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

@foundmyfitness The brain is just like a muscle, the more you use it the more it expands with the help of chemicals like BDNF and VEGF, the less you use it the more it atrophy’s. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

@NTFabiano Since the autoreceptor is turned on during sleep, sleep deprivation disallows it to regulate neurotransmitters which may result in a surge of dopamine a la mania. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

Dopamine is a reward chemical that evolution used to reward survivalist behavior since evolution really only works by mutation, it found a way to encourage survival of the fittest. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire

@PhysInHistory Since entropy rules the universe, the strangest thing is that life exists at all. Steven LeskMD author of Footprints of Schizophrenia: the Evolutionary Roots of Mental Illness and Entropy’s Desire