Kirsty Smitten
@SmittenKirsty
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Co-founder and CEO of MetalloBio, a company developing first-in-class ruthenium antimicrobial compounds| AMR | Forbes 30 Under 30 2020
England, United Kingdom
Joined December 2018
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Pinned Tweet
As most of you know I've started a blog documenting my
#cancer
journey to increase awareness of
#angiosarcoma
and
#youngadultcancer
.
In today's post I've written about the biopsies that led to my diagnosis including a
#thoracotomy
.
#nevertooyoung
23
24
51
I hit an academic milestone today. I’ve been asked to be a keynote speaker at a clinical microbiology conference 😱.
@OpenAcademics
@PhDVoice
@AcademicChatter
@PhDspeaks
#WomenInSTEM
#AcademicTwitter
@PhDfriendSana
@thoughtsofaphd
@PhDForum
11
8
231
So proud to have been awarded Innovate UK grant funding for MetalloBio! My first large grant proposal accepted 🍾🍾🍾
@OpenAcademics
@AcademicChatter
@AcademicDilemma
@chanceacademic
@PhDForum
@PhDfriendSana
@PhDVoice
9
5
131
Rollercoaster of a day:
1. Awarded a highly competitive Innovate Grant (gives me success in every Innovate Grant Call I’ve applied for now).
2. My oncologist tells me I’m terminal at 28 years old. Any good ideas on what to do with my last 7 months of life?
#nevertooyoung
36
1
100
Smiles all round today as I finished my thesis intro draft and it’s a snow day! 🙌
@OpenAcademics
@thephdstory
@AcademicChatter
@PhDVoice
@PhDForum
@PhDfriendSana
1
4
93
8 years ago I walked into my personal tutor’s office as a chemistry undergraduate, today we start our business plan training for our biotech company
@GroupThomas
. Hard work pays off!
@PhDVoice
@PhDForum
@PhDfriendSana
@OpenAcademics
@AcademicChatter
@thephdstory
@NxNWpartners
1
5
92
So today I turn 29, bit of a strange birthday. It’s the first without my Dad and statistically it’s probably my last. 5 months ago we didn’t think I’d even make it here so that’s something to celebrate 🎉. Now onto fighting to make 30!
19
3
102
For new
#PhD
students I wrote a blog post a while ago for FindAPhD about surviving the initial first month of madness. Hope this can help.
#AcademicTwitter
@PhDVoice
@academicvoices
@AcademicDilemma
@AcademicChatter
@OpenAcademics
#WomenInSTEM
1
23
80
For anyone following my cancer journey, the scans were good! I’ve had no spread and the heart tumour is still stable with a some shrinkage! I’m all okay for surgery! Surgery will be in the next couple of weeks!
#cancer
#sarcoma
#sarcomauk
14
0
84
Why are 8-12 minute conference presentations so much harder to do than longer ones 😓.
@AcademicChatter
@PhDVoice
@thoughtsofaphd
@OpenAcademics
#AcademicTwitter
@PhDfriendSana
#phdlife
15
6
74
Update - i’m the
#FSBawards
Young Entrepreneur of the Year. The comments I’ve had from everyone today have been amazing!
11
6
69
How are you supposed to get your thesis finished when your working from home buddy is this cute? 🤷♀️
#phdchat
#AcademicTwitter
@OpenAcademics
@PhDVoice
@PhDfriendSana
@PhDForum
@AcademicDilemma
@AcademicChatter
6
7
66
Why are zoom presentations equally as daunting as in person ones? I’m literally sat in a room on my own yet I’m still shaking 🤷🏻♀️😂
#phd
#AcademicTwitter
@OpenAcademics
@academicvoices
@AcademicDilemma
@PhDVoice
@PhDfriendSana
@PhDForum
10
6
65
Chemo on Wednesday, FSB Awards for Young Entreprenuer of the Year Award on Thursday.
Smashing life, I think that deserves the champagne!
@FSB_Voice
#fsbawards
#champersnow
10
8
68
My tumour has shrunk! We were expecting growth, this was technically a baseline scan and is being compared to Novembers scan.
It’s shrunk 1cm x 0.5cm but realistically it’s likely shrunk 2-3cm.
I’m documenting my journey to raise awareness -
8
1
66
The news is out, I have been awarded an Innovate UK Women in Innovation award 🎉.
📣 Meet the winners of
@innovateuk
’s
#WomenInInnovation
Awards 2022/23 who are making the world a better place. Find out more about these trailblazing women; each awarded a £50K grant, 1:1 business coaching & so much more:
#WomenInnovate
#InnovateUKEDGE
2
22
53
4
1
63
Baileys’s ‘do I have to hear you practice your presentation again’ face!
@OpenAcademics
@PhDVoice
@PhDfriendSana
@PhDForum
@AcademicChatter
2
4
58
The feeling after every paper/grant rejection -
@OpenAcademics
@AcademicChatter
@PhDfriendSana
@PhdExhausted
@AcademicDilemma
@PhDVoice
#AcademicChatter
#phdchat
7
8
54
I'm not sure if I should be happy or scared but I have a surgery date for next week! This is a million miles from where we were in January. Now I just need everyone's fingers crossed for a negative margin!
10
1
56
Excited to announce I’ve been nominated for The Women in Tech Global Awards 2020 Rising Star in STEM
@WomenTechNet
@AcademicChatter
@PhDVoice
@PhDForum
@OpenAcademics
#WomenInSTEM
#PhD
#womenintech
4
5
50
Didn’t win the first bottle of champagne but won the Young Entrepreneur of the Year Award - and a standing ovation 🎉
Can we have champagne to celebrate?
Table 38 - MetalloBio
@FSB_Voice
#FSBAwards
7
5
56
Sitting in the
#chemotherapy
ward and I’m younger than the other 29 people in here by at least 30 years. I know
#cancer
affects 1 in 2 people but I never thought it would hit me at 28 years old.
I can’t urge people enough to get any health issues checked early!
#nevertooyoung
6
1
51
It should be illegal to be sat up past 3.00 am working 🙄. When does life slow down - asking for a friend? 😂
#phdchat
#AcademicTwitter
@PhDVoice
@PhDvent
@PhDForum
@AcademicChatter
@OpenAcademics
@AcademicDilemma
7
4
44
At every future interview:
@thephdstory
@AcademicDilemma
@OpenAcademics
@PhDVoice
@PhDfriendSana
#AcademicTwitter
#PhD
@thoughtsofaphd
@PhDForum
1
8
50
Anyone else hate afternoon pitches/presentations? I spend the whole morning building up my nerves 😅
@PhDForum
@OpenAcademics
@PhDfriendSana
@PhDVoice
@AcademicChatter
4
4
41
Academia is so up and down it’s draining. In the morning you have a good partnering meeting, by lunch time you’ve been served a grant rejection 🙄.
@AcademicDilemma
@AcademicChatter
@PhDVoice
@PhDfriendSana
@thoughtsofaphd
@PhDForum
@PhDspeaks
#AcademicTwitter
2
4
46
Update - my oncologist phoned this morning saying the appointment will be rearranged for next week, he also said they’re really happy with the scans I’m having a good response to chemo and the plan is to operate!
7
0
46
Pleased to have won first prize for my talk on ruthenium antimicrobial compounds at The Antibiotic Discovery Accelerator Network (ABX) meeting today.
#phdchat
#AntimicrobialResistance
@PhDVoice
@OpenAcademics
@AcademicChatter
@PhDForum
@PhDfriendSana
5
5
47
Is this one of the reasons we do a
#phd
? So we can say this.
@OpenAcademics
@academicvoices
@AcademicDilemma
@AcademicChatter
@PhDVoice
#AcademicTwitter
10
4
45
After a very intense 2 weeks medically it’s nice to come back to work and see we’ve been awarded another Innovate UK grant to progress our antimicrobial technology towards GLP-tox studies!
4
0
44
The pitch went well and we are on track to form our biotech spin-out company MetalloBio this year! From PhD to entrepreneur 😱. Scary but exciting times ahead!
@GroupThomas
@PhDVoice
@PhDfriendSana
@PhDForum
@OpenAcademics
@AcademicChatter
4
6
44
Surgery update, they got all the tumour out on Monday but unfortunately on Wednesday I had type 1 respiratory failure and Ct-scans have shows a severe infection in my right lung. I’ve been in intensive care since whilst they try to find out what’s up :(
11
2
42
I’ve just started a two volume grant proposal, where volume 1 is 25 pages 😱. Send help and coffee ☕️.
@OpenAcademics
@PhDForum
@PhDVoice
@PhDfriendSana
@AcademicChatter
@AcademicDilemma
3
3
41
Me constantly refreshing my emails to hear the outcome of our funding.
@OpenAcademics
@PhDVoice
@PhDForum
@PhDfriendSana
@AcademicChatter
@thephdstory
2
3
39
I’m having one of those days where I sit down to do an hours work at 7.00 pm and all of a sudden it’s 12.30 am 🙄
#phd
#AcademicTwitter
@thephdstory
@AcademicDilemma
@AcademicChatter
0
1
39
Our international patent application for my ruthenium antimicrobials compounds has been published today 🥳.
#amr
#antimicrobialresistance
@GroupThomas
@OpenAcademics
@PhDVoice
@PhDForum
@PhDspeaks
@thoughtsofaphd
@PhDfriendSana
@thephdstory
2
5
38
Excited to announce I’ve been selected as a finalist for the Women Tech Global Awards 2020 - Rising Star in STEM.
@WomenTechNet
#WomenInSTEM
@OpenAcademics
@PhDForum
@AcademicDilemma
#phd
0
6
37
My emotional rollercoaster day in academia:
1. Present for my early career impact award.
2. Progress to Stage 2 of a fellowship application.
3. Boom - rejected from a different fellowship application.
@OpenAcademics
@PhDVoice
@AcademicDilemma
@PhDfriendSana
@AcademicChatter
0
6
34
A bit of
#MondayMotivation
for you
#AcademicTwitter
.
Let’s grow our networks:
1. Introduce your research
2. Tag 2 friends to get involved
3. What motivates you most during your
#PhD
?
@thoughtsofaphd
@OpenAcademics
@PhDVoice
@AcademicChatter
4
3
30
Amazed to have been selected for the 2020 Forbes 30 Under 30 in Science and Healthcare for my work on ruthenium antimicrobial compounds.
#ForbesUnder30
#AcademicTwitter
@sheffielduni
@SheffieldChem
@GroupThomas
5
3
31
@NeuroSarcastic
Hey academic twitter-
1. Ruthenium, antimicrobials, bacteria.
2. Sheffield, UK.
2
0
28
Seeing a lot of grant/paper rejection posts on my feed, keep going everyone! Academia’s and emotional rollercoaster but when some get accepted it’ll all be worth it!
@OpenAcademics
@PhDfriendSana
@PhDVoice
@PhDForum
@AcademicChatter
@AcademicDilemma
0
3
31
Championing
#WomenInSTEM
@MillionStem
@OpenAcademics
@thoughtsofaphd
@PhDVoice
@PhDfriendSana
@500womensci
1
5
33
@PhDfriendSana
@AcademicChatter
@HaphdS
@What2doWithTHAT
I have the same question but in reverse is it okay for us to email our supervisor at the weekend?
6
1
28
I have been nominated as the Sarcoma UK young sarcoma voice of the year. Not sure what chance I have against a 24.7 million subscribers YouTube sensation 😂. But you can vote for me here -
5
4
31
Proud to have been awarded a Royal Academy of Engineering Enterprise Fellowship
MetalloBio's CEO,
@SmittenKirsty
, has been awarded a Royal Academy of Engineering Enterprise Fellowship. The Fellowship will support MetalloBio in the development of antimicrobial materials.
0
1
14
6
0
31
I was interviewed on my
#PhD
and career yesterday on
@biopatrika
. I spoke a lot about my supervisor
@GroupThomas
My advice, the supervisor is just as important as the project. I wouldn’t have my career without Jim. He’s the most supportive person I know and I’m very grateful.
3
3
31
On the top of the academic emotional rollercoaster today. Our MRC Confidence in Concept grant to develop our antimicrobial compounds into a sol-gel coating has been accepted!
@OpenAcademics
@AcademicChatter
@PhDVoice
@PhDfriendSana
@PhDForum
0
2
31
We have started our ICURe programme today exploring the commercial potential for our lead ruthenium antimicrobial compounds
@GroupThomas
@NxNWpartners
@innovateuk
#icure
#icurenxnw
0
7
31
Submitted my thesis and a 4-year grant proposal for
@BioMetallo
today. I think it’s time for a big glass of wine!
1
0
28
Another successful end to the week for
@BioMetallo
we’ve been accepted onto the second stage of the biggest AMR grant going, signed the letter of intent with our lead investor and I’m having surgery!
Who said you can’t run a company well whilst battling heart cancer?
0
3
31
At the
@MedilinkUK
healthcare awards because
@BioMetallo
is up for the Start-up of the Year Award!
Star struck because
@RichPaxman
, CEO of
@scalpcooling
, the machine saving my hair in chemo is here. Thank you for letting me keep a piece of me in all the rubbish that is cancer.
0
2
27
The irony around developing a new drug for antibiotic resistance and then spending the last 5 weeks fighting multiple antibiotic resistant infections post surgery. Having pneumonia back to back three times in a row with different pathogens is 0 fun!
6
2
28
We won the Rebel Start Up Award for being the most disruptive start up but then the night was made when we won the overall award for evening out of all the finalists from the 31 award categories of the night!
A huge congratulations to the team at MetalloBio for being crowned the overall winner of the North East, Yorkshire and the Humber StartUp Awards 2023!🏆
All the best for the future guys🎉
#SUA2023
#StartUpAwards
#StartUpWinners
1
0
2
2
2
28
At 28 years old I was diagnosed with a cancer that affects 1 in 20 million and has a 7 month prognosis. I have started a blog to document my journey, increase awareness and improve future patient outcomes. The first post is out today - share if possible.
0
14
26
In my continuous good luck my tumour turned resistant to paclitaxel.
My follow up chemo will be doxorubicin (the Red Devil) and isofamide. Renowned to be one of the toughest chemo regimes :(.
Followed by a potential first ever treatment of proton beam with isofamide.
6
1
23
Showing my innovator creativity here - freezer socks to cure the face burning rash caused by paclitaxel.
Next I’ll be designing my own cooling face masks. Watch this space 👀.
#chemo
#cancer
#CancerAwareness
2
0
23
The moment I got a standing ovation for my speech at the FSB Awards
Watch our CEO
@SmittenKirsty
interview for winning the FSB Young Entrepreneur of the Year 2023
1
1
8
0
1
26
@ZJAyres
@AcademicChatter
Hey 🖐 I’m kirsty, outside of my research I love playing football and hockey and walking my dog bailey
1
0
23
Happy to have been awarded the
@healthtechworld
Young Health Tech Leader of the Year Award.
Simon keeps joking we'll need a trophy cabinet in the office soon.
1
1
21
The last 3 weeks have made me realise just how dangerous it is for immunocompromised patients to be in hospital.
I’ve been in hospital again this week for a potential clot and have ended up with a multi-drug resistant lung infection. Infection control needs to be better!
2
2
22
Really pleased to announce
@BioMetallo
won the
@RoySocChem
Emerging Technologies Health Category after impressing an expert panel including representatives from AstraZeneca and Eli Lilly.
The validation, support package and funding will accelerate our technologies development.
And finally, please join us in congratulating this year’s
#RSCEmergingTech
competition Health category winner –
@SmittenKirsty
at MetalloBio Ltd.
Their ruthenium antimicrobial platform technology can be used to treat multi-drug resistant infections.
#RSCIndustry
#ETC10
0
2
12
2
2
23
2 weeks ago I had open heart surgery to remove a cardiac angiosarcoma tumour from the right atrium of my heart. In this week's blog post I discuss the operation and going into type 1 respiratory failure.
3
1
20
We had a brilliant experience on the
#ICURe
bootcamp this week developing our business model and market discovery action plan. Please contact us if you are interested in a highly active novel antimicrobial compound.
@GroupThomas
@NxNWpartners
@innovateuk
#ICURe
#ICURenxnw
0
5
24
Anyone else relying on unlimited coffee to get them through the first day back in the lab?
@OpenAcademics
@chanceacademic
@AcademicChatter
@PhDfriendSana
@PhDVoice
@PhDForum
@AcademicDilemma
2
1
21
Continuing to run a company whilst losing a parent and going through a really serious medical problem myself is one of the hardest things I’ve ever had to do.
I’m so grateful for the amazing MetalloBio team ❤️
1
1
22
Recently I won the Innovate UK Women in Innovation Award. Yesterday I was interviewed about MetalloBio and the Award on
@yorkshirelive
. Also today I’ll be BBC Radio Sheffield the Paulette Edwards Show at 10.10 am.
1
4
23
A nice end to the Metals in Medicine workshop, winning a poster presentation prize for my work on ruthenium polypyridyl antimicrobials.
@GroupThomas
@metals_in
4
0
22
I may not have gained many lab skills during lockdown but I've definitely upped my breakfast creativity game.
#chemistwhocooks
#cookingischemistry
@OpenAcademics
@PhDfriendSana
@thoughtsofaphd
@PhDVoice
@AcademicDilemma
@AcademicChatter
@PhDspeaks
@thephdstory
@liveyourPhD
1
5
21
Really proud to have been awarded a highly competitive Innovate UK grant today. Very big day for
@BioMetallo
!
2
0
23
Our antimicrobial drug development spin-out company MetalloBio officially incorporated today! Exciting but scary times ahead
@GroupThomas
🍾🍾🍾.
@OpenAcademics
@PhDForum
@PhDfriendSana
@PhDVoice
@AcademicChatter
@chanceacademic
1
3
21
Whilst sitting in hospital waiting for my surgery I have finally started the blog back up. It's been a busy few weeks. In this post I discuss the second opinion.
3
0
21
Proud to have
@BioMetallo
first option deal on my desk ready to sign. A big milestone for the company!
3
1
21
Pleased to have been accepted into the
@innovateuk
funded
@NxNWpartners
ICURe programme
@GroupThomas
3
0
21
We really do need that trophy cabinet now!
Congratulations to my
@BioMetallo
team for winning the
@MedilinkUK
Start-up of the Year at the National Medilink Healthcare Business Awards last night!
3
0
21
Update on last week’s post - the pitch went well and we secured business planning funding for the next stages of the ICURe programme!
@GroupThomas
0
2
21
I’ve gone on holiday for a break with bailey and it’s lovely but the bed is so hard it’s made all my joints and muscles ache - chemo perks.
0
0
18
Every chemo seems to be hitting me harder. I fell asleep for 2 hours after today and some side effects have already started.
My haemoglobin plummeted between my last two bloods which explains the exhaustion and the patchwork quilts bruises on my legs!
10
0
19
Our website is live!
You can learn about the antimicrobial compounds we develop, follow the progress of MetalloBio and read our weekly blog posts here -
#ICURe
#innovateuk
#ICURenxnw
#AcademicTwitter
#amr
@OpenAcademics
@GroupThomas
0
6
19
Starting the week on a high with a keynote lecturer invitation to a Chemical Biology conference in Brisbane in December!
0
1
19
House renovation update, finished the panelling and new carpets just the built in wardrobe to go and the bedroom is done 💪🏻👌
0
0
15
It’s strangely therapeutic doing a column on the weekend, the lab is so quiet and peaceful 🥰.
1
0
18
Note to self don’t juggle moving house and writing a big grant application - spoiler alert this piece of wardrobe did come apart 😂.
@PhDfriendSana
@OpenAcademics
@PhDVoice
@AcademicChatter
@PhDForum
1
3
17
Me chasing down my
#PhD
graduation.
@OpenAcademics
@AcademicChatter
@PhDfriendSana
@PhDVoice
#AcademicTwitter
@PhDForum
0
2
18
We’ve just had a paper accepted in ACS Pharmacology & Translational Science 🍾 . Thanks to an excellent collaboration with the McLean group at
@TrentUni
.
@GroupThomas
@SamMacX13
1
3
17
By 2050 antimicrobial resistance is expected to cause 10 million deaths per year globally. Listen to our interview on CBS news last year where we discuss this threat and how our compounds can be used to reduce these deaths.
@GroupThomas
#AMR
#ICURe
1
4
17
Really pleased to have come second in the
#BrightSCIdea
competition! Thank you judges for your positive feedback on our business proposal!
@SCIupdate
@FlissNoakes
@GroupThomas
0
0
17
MetalloBio has recently been awarded a joint grant with Nottingham Trent University to explore the mechanism of action of our lead compounds. Nottingham is hiring a research associate for this position.
Please share and apply using the link below.
0
8
18
A nice end to October having our paper on ‘Ruthenium based antimicrobial theranostics – using nanoscopy to identify therapeutic targets and resistance mechanisms in Staphylococcus aureus’ accepted into Chemical Science
@GroupThomas
@ChemicalScience
@Bernardino_Lab
2
3
17
Non-academic related post. Just received my hockey trophy for last season and it’s the creepiest thing I’ve ever seen it’s like they forgot to finish the face 😂.
2
1
15
Brilliant day today at the
@FSB_Voice
2023 awards. I picked up Young Entrepreneur of the Year and
@BioMetallo
won the overall award - Small Business of the Year.
Thank you to my amazing team for all the hard work and amazing support you give me!
Congratulations to our CEO
@SmittenKirsty
for winning the
@FSB_Voice
UK Young Entrepreneur of the Year and to the whole team for winning the overall award Small Business of the Year.
An excellent accolade of the amazing work we have been doing at MetalloBio to combat AMR.
0
1
11
2
1
18
Chemist turned nail artist - chemo giving me too much spare time 😂
2
0
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@OpenAcademics
Hey everyone.
1. I’m kirsty I’m a PhD researcher at the university of Sheffield. I make ruthenium antimicrobial compounds to treat multi-drug resistant infections.
2.
#AntimicrobialResistance
#AMR
0
0
16
Second ChemSci article incoming soon on a DNA targeting Osmium antimicrobial complex, two ChemSci papers accepted in a week, a rare good week in academia and
@charlotte_kiker
’s first paper!
2
2
17
We are kicking off the Superbugs Under the Spotlight mini-series with Pseudomonas aeruginosa. The mini-series aims to increase awareness of
#Superbugs
to help in the fight against
#AMR
.
@OpenAcademics
@saveantibiotics
@PhDVoice
@AcademicChatter
#PhD
0
5
17
@NeuroSarcastic
Hey everyone :)
1. Ruthenium, antimicrobials, bacteria.
2. I like playing football, hockey and walking my dog.
3.
0
0
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