Sho Goh Lab
@ShoGohLab
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We find out where RNA modifications are, what they do, how they do it and why that matters. Always looking to hire new postdocs
Joined May 2019
Achievement Unlocked! @huihuian521, our 1st PhD student’s 1st 1st-author paper! Out now in @MolecularCell 🧵 We identify the 1st m6Am Reader and uncover a novel and unexpected mechanistic role for this abundant yet enigmatic mRNA modification. (1)
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RT @JonathanGoeke: Very happy to release the single cell and spatial long read RNA seq module for our transcript discovery and quantificati…
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RT @NikoMcCarty: Gregor Mendel is so much cooler, and his life so much richer, than your high school biology class might suggest. Here are…
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Interesting new study on nucleosome wrapping states from our SZBL colleague Haizhen Long
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RT @xwang_lk: It is just so sad that the #NeurIPS2024 main conference ended with such a racist remark by a faculty when talking about ethi…
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Congrats to our colleague Qin Peng on the development of a m6A live-cell imaging method. Glad to have helped out on this work.
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RT @Scwin2: Really excited to share the latest paper from our lab! Check out our tool and reference here: https://…
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"It is certainly possible that... the genome sequence alone does not define the cell types... genome itself is a molecule with epigenetic chemical modifications that aren’t accounted for in the genome sequence" RNA modifications can be potential cell type definers too
In @CellCellPress, I share a major conceptual challenge for biology in the next decade, inspired by Crick’s Central Dogma: understanding information flow in the cell, the smallest indivisible unit of life
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RT @Nature: A scientist who successfully treated her own breast cancer by injecting the tumour with lab-grown viruses has sparked discussio…
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RT @STOPlabPI: Cool: my favourite protein turns out to read m6Am! Impressive & super interesting paper. Congrats and great job @huihuian52…
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RT @MolecularCell: m6Am sequesters PCF11 to suppress premature termination and drive neuroblastoma differentiation
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@arispapargyriou I agree that it's dysfunctional... but said dysfunctionality also allowed me to still catch my train when my flight arrived 1h late at Frankfurt airport
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I've always been a fan of @SuzukiRNALab's papers so I'm beyond honoured for them to write a Preview on our recent m6Am reader story
Cap-specific m6Am modification: A transcriptional anti-terminator by sequestering PCF11 with implications for neuroblastoma therapy
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RT @huihuian521: First Author Milestone: My debut paper as first author! Out now in @MolecularCell. Our study identifies the transcription…
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RT @MolecularCell: Online Now: m6Am sequesters PCF11 to suppress premature termination and drive neuroblastoma differentiation https://t.co…
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