I am excited to share that I have joined as an assistant professor of
@CheEnggIITB
. I am grateful to all my colleagues and mentors, especially my advisors Stas Shvartsman and
@Aspakowitz
, as well as my friends, teachers and family for their support in the preceding journey.
Self-organization of actively forced slender fibers (microtubules) immersed in a fluid (cytoplasm) generates coherent flow in 3D confinements (cells). Our study featured in
@NaturePhysics
shows that using large scale simulations and live imaging of fruit fly oocytes.
Admission portals for Masters and PhD programs
@iitbombay
are open. Prospective applicants pls consider applying to programs of
@CheEnggIITB
. I am excited to host first grad student(s) in my group . RTs highly appreciated.
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How do we construct the connectivity between loci of chromosome marked with the same color? We propose an algorithm founded on polymer physics in this work with
@AsheshGhosh1
, Alistair Boettiger, and
@ASpakowitz
out in
@BiophysJ
How does spatial and temporal correlation of active forces impact structure and dynamics of biopolymers? We adapt the physics of flexible polymers and demonstrate using an e.g. of point fluctuation in this work with
@AsheshGhosh1
and
@ASpakowitz
now online in
@softmatter
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@sayanta48457362
and colleagues develop a model for Drosophila embryogenesis to illustrate how computational models can be used for quantitative evaluation of candidate mechanisms of embryonic development ().
How do fruit flies maintain left-right symmetry during gastrulation? We show that using genetic perturbation, light sheet microscopy and tissue cartography. It was exciting to be part of this work with
@celia_smits
and Stas in collaboration with Vishank and
@StreichanS
.
Really pleased to share my own paper for once, just out in Current Biology! We looked at bilateral symmetry during Drosophila gastrulation. I mainly recommend reading it for the beautiful SVD analysis
@SayantanD2
performed though.
Big thanks to all my collaborators and mentors in this project:
@RezaFarhadifar
, Wen Lu, Gokberk Kabacaoğlu, Robert Blackwell, David Stein, Margot Lakonishok,
@volodya_gelfand
, Stas Shvartsman, and Mike Shelley. Please check out at
My upcoming research group plans to work on building computational models for self-organization in biological systems across scales with a vision of writing down the design principles of functional biomaterials. Here is a link to the website
I’m super excited to share my most recent work on germ fate specification! We optogenetically perturbed mesoderm invagination in Drosophila embryos to learn how cells choose between endodermal and mesodermal fates:
Excited to share updated FateMap paper in
@Nature
w
@arjunrajlab
. We show that diverse resistant fates can arise from homogenous cells upon drug exposure+ the fates over weeks/months in drug are decided even before drug addition
@pennbioeng
@NorthwesternU
I am interested to investigate self-organization of living materials across scales using theoretical and computational tools . For more details please visit .
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