Rosenblatt Lab
@RosenblattLab
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Cell extrusion specialists 🥼 We're a bunch of cell biologists studying how cell extrusion impacts #asthma and #cancer 🔬🇬🇧
King's College London
Joined August 2019
Nature research paper: Energy deficiency selects crowded live epithelial cells for extrusion https://t.co/Bbb7HokmPp
nature.com
Nature - Crowded epithelial cells with the least energy and membrane potential are selected for extrusion.
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Our paper showing epithelial cells measure electrical potential to decide which ones to eliminate by extrusion came out today in Nature. The weakest link: how cells use electricity to eliminate their neighbours to maintain healthy barriers @TheCrick
crick.ac.uk
Researchers at the Francis Crick Institute and King’s College London have uncovered a surprising role for electricity in keeping our body’s protective cell layers healthy, which could potentially...
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Hero alert. My amazing colleague Carola Vinuesa used Science to get a wrongfully imprisoned woman freed after 20 years. The culprit: a mutation https://t.co/nbNCQDmKFH
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Very proud for our newly minted Dr. Faith Fore--that's Dr.4 to you!
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Thrilled & incredibly honoured to receive a @wellcometrust Early-Career Award! 🙌 Can't wait to start my research on how epithelial tissues maintain homeostasis at @TheCrick, @KingsCollegeLon & the @RosenblattLab! 🧪🔬🐟 Stay tuned - I’ll be hiring soon!
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Check out our recent review with Paul Martin & Gisli Jenkins on how imperfect wound healing can set the stage for disease, discussing how environment and general wear and tear we accumulate with age contributes to many diseases.
science.org
Although the age of the genome gave us much insight about how our organs fail with disease, it also suggested that diseases do not arise from mutations alone; rather, they develop as we age. In this...
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Please share: we're listing a cherry of a project here and we'd like to recruit!
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Excited to recruit!
Are you interested in doing a #PhD in #cancerresearch & #biotherapeutics? Are you of black heritage? 🔬👩🏿🔬👨🏿🔬🧫🧪 Applications for our 4-year PhD programme for Black Leaders in Cancer are open now! @TheCrick @uclcancer @QMBCI @KingsCollegeLon
https://t.co/X4U0kHhjeK
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Imagine a world where beach and science are fused.. you don't have to dream...
Join us! Mechanosignalling, ion channels, and neurodegenerative diseases. Nice building, even nicer people. Barcelona and all that. Publicly funded health care. Bike to work. By the beach. C'mon!
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Congratulations to our incoming director Edith Heard, current director of @embl, on being awarded the Croonian Medal from the @royalsociety 🏅 Learn more about Edith’s research and her recent award 👇 https://t.co/8zssziRsQr
crick.ac.uk
Edith Heard, incoming Crick chief executive, has been awarded the Croonian Medal and Lecture from the Royal Society for being a leading figure in X chromosome biology.
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Very proud of our own Snezkha Oliferenko for becoming an EMBO member! https://t.co/Jsp8oDgGyV
kcl.ac.uk
In EMBO’s 60th anniversary year, 100 new Members and 20 Associate Members join the EMBO community
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We are delighted to announce that Professor Edith Heard has been appointed as our new director and chief executive! Edith, who is currently director-general at @EMBL, will succeed Paul Nurse in leading the Crick from the summer of 2025. 🔗 https://t.co/CcJR4TFxbF
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This paper is remarkable showing hope for RNAi based vaccines--no T cells and B cells are needed. Just good old innate immunity lasting at least 90 days. https://t.co/nteyLFJkze
pnas.org
Global control of infectious diseases depends on the continuous development and deployment of diverse vaccination strategies. Currently available l...
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Saranne Mitchell knocking it out of the park. Talking about energy and extrusion for her Raff Award @Official_BSCB
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We can prevent this destruction using inhibitors of extrusion--especially gadolinium. We hope that this will not only prevent the acute features of asthma but also calm down airway damage and inflammatory cycle that promote further attacks.
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Although asthma is deemed an inflammatory disease, the life-threatening feature is airway constriction. We show that this constriction causes so much crowding-induced extrusion that it destroys the airway lining, leading to the inflammation and mucus secretion.
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