Rameen Beroukhim
@RameenBeroukhim
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Joined June 2022
A really interesting paper arguing against our thesis that the temozolomide signature is mediated in part by loss of mismatch repair: (I should have posted this earlier but have been avoiding twitter due to its ~recent changes)
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@nellage @RonDePinho @Nature @nellage, not all frequent genetic events in cancer are frequent due to effects on fitness. For example, deletions of fragile site genes like FHIT. Observed frequency is a balance between fitness effects and ease of generation
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@game_of_chroms Hi @game_of_chroms, I told you that I take aneuploidies seriously! Hope your work is going well.
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@RonDePinho @Nature Thanks, @RonDePinho, for citing our paper! But did you mean to cite @JSheltzer's paper on aneuploidy addiction?
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RT @alisontaylorlab: Out @Nature today! Excited to finally share our work led by Juliann Shih in collab w/ @RameenBeroukhim. Our algorithm…
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RT @boehmjesse: (1/7) The approach researchers use for #CRISPR guide design can accidentally perpetuate ancestry-related false negatives in…
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RT @NewsfromScience: A new analysis finds that failing to account for ancestry slightly skewed a massive sweep for cancer genes, causing it…
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I hadn't expected this one Detection and localization of early- and late-stage cancers using platelet RNA
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Nice paper by @SohrabShah and colleagues on biomarkers of immunotherapy response Multimodal integration of radiology, pathology and genomics for prediction of response to PD-(L)1 blockade in patie…
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Paper is finally out in @NatureGenet! "Cancer cell states recur across tumor types and form specific interactions with the tumor microenvironment" Check out our catalog of conserved cancer cell states defined by scRNA-Seq & ST. Congrats @BarkleyDalia!
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Nice review on ecDNA by Anton Henssen and Roel Verhaak labs
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RT @KeithLigon5: Out today (Happy4th🇺🇸!) Bando/Ligon/Beroukhim team manuscript led by Frank Dubois w/AMAZING crunch of WGS on 179 pHGG defi…
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