Harriet Gee
@RadOncDoc_Gee
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#RadOnc @CPMCCwestmead, #PhysicianScientist, Clin A/Prof @sydney_uni. Adjunct Research Scientist @CMRI. #radbio of #SABR/#SBRT. Usual disclaimers.
Sydney, New South Wales
Joined January 2017
@kristinasci @TheCesareLab @Eric73363938 @hildaApickett @szmyd_radoslaw @SiennaCasolin @AnnaGManjon @MelliW92 @Lea_Cavalli_ Thank you so much Kristina!
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@gerryhanna @DrewMoghanaki @Mat_Guc @HenningWillers @_ShankarSiva @HegiFiona @TargetingCancer @brokendna @RogerRogergr @K_Butterworth @JacinthaOS @aislingbarryro @OOneill4 @lauremarignol Wonderful work Gerry from this amazing group of people....perhaps we can be honorary irish!
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9/ Hypothesis - all work in vitro so far lots of provisos - would be that tumours with HR defects would respond better to the combination of SBRT/SABR and immunotherapy.
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8/ Brilliant team of scientists and collaborators @szmyd_radoslaw @SiennaCasolin, lucy french, @AnnaGManjon, @MelliW92, lea cavalli, Chris Nelson, Scott Page, @andrewdhawan @Eric73363938 @hildaApickett. Gratitude for friendship and science
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7/ We are grateful for much support. This project was not possible without @CMRI_AUS , funding from NHMRC and ARC and longstanding support of the Western Sydney Local Health District Radiation Oncology Network. Our institutions including @Sydney_Uni
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6/ This opens up new therapeutic opportunities to personalise the combination of SABR/SBRT and immunotherapy and run biomarker driven trials
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5/ Conversely more error prone repair pathways lead to passage through mitosis with immune-stimulating DNA and RNA species
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4/ Key take away for the rad onc community: timing and mode of cell death after ablative radiotherapy is dependent DNA repair pathway, with homologous recombination leading to mitotic 'non-immunogenic' cell death
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2/ Wonderful summary of the science from @TheCesareLab @CMRI_AUS
2/This work was led by out exceptionally talented post-doc @szmyd_radoslaw and co-supervised by @RadOncDoc_Gee. Long 🧵below with images and movies shared from the open access paper. TL;DR double strand break repair determines the manner in which irradiated cells die.
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@TheCesareLab @CMRI_AUS has a fabulous summary of the science - click through below
2/This work was led by out exceptionally talented post-doc @szmyd_radoslaw and co-supervised by @RadOncDoc_Gee. Long 🧵below with images and movies shared from the open access paper. TL;DR double strand break repair determines the manner in which irradiated cells die.
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1/ Thrilled that our paper is out today in @NatureCellBio. A collaboration between WSLHD Radiation Oncology Network and @TheCesareLab led by @szmyd_radoslaw
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@rsamstein @ScienceMagazine @chirag_msk @MiriamSaffern @EricWil39327976 @HannaMOllila @diegochowell Congratulations, very interesting and important work!
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RT @CMRI_AUS: @TheCesareLab @NatureCellBio Congratulations to our Genome Integrity Unit @szmyd_radoslaw and @RadOncDoc_Gee for this amazing…
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@DrewMoghanaki important study, thanks for posting and for commenting. one for you @lucindaburke
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RT @imagexinstitute: We've got another Postdoc Research Associate position! Join us to advance lung function imaging during radiation thera…
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RT @DrewMoghanaki: The largest randomized phase III trial evaluating lung SBRT publishes a secondary analysis of 30 patients with ultra cen…
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RT @RANZCRcollege: There are a variety of funding opportunities available as part of the RANZCR Grants, Awards and Fellowships program. He…
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