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The morphological structure and function of the fallopian tube epithelium are shown to be impaired in patients with tubal endometriosis, in this new paper from a team at Shanghai Key Laboratory of Embryo Original Diseases.

To celebrate the release of Netflix film, Joy today our editors of past and present have created this video sharing their thoughts and experiences on working with Sir Robert Edwards and the legacy of his groundbreaking work.

In this study, Wei Wu and team in Nanjing, use mice IVM to explore the effect of putrescine on the in vitro maturation of oocytes from reproductively old mice.

In this real-world observational study in women with subfertility, freezing all available embryos was the preferred treatment strategy, with planned PGT and risk of OHSS being the most frequent indications to select this approach.

This study shows, through a large series of pregnancies conceived via spontaneous conception (SC), IVF and fresh embryo transfers, that trophectoderm biopsy may be associated with lower levels of maternal serum PlGF at 8 to 13-6 gestational weeks.

This review article highlights technical and methodological limitations constraining the clinical use of PGT based on blastocentesis. It recommends prospective studies refine the technique and enhance the predictive power of the BF-DNA amplification.

In this new Commentary article, R. John Aitken and Parviz Gharagozloo call for robust, user-friendly, point-of-care assays to diagnose and monitor oxidative stress in patients’ semen to better understand its role in the etiology male infertility.

Analyzing numerous kinetic combinations annotated with artificial intelligence reveals patterns which can help distinguish embryos that are competent enough for early pregnancy but not for clinical pregnancy.

This study attempts to find new methods for promoting endometrial repair after induction of labor and abortion to prevent occurrence of intrauterine adhesions (IUA), reduce the incidence of re-adhesions after IUA, and assist in the treatment of severe IUA

On the evidence presented in this paper, the authors advise that RC+ embryos achieving a high-quality blastocyst stage should be considered and scored equal to their RC negative counterparts.

This new review presents the latest findings on the biomechanical properties of the ovary, demonstrating the significance of the ovarian environment in supporting folliculogenesis during reproductive life.

This new paper provides valuable insights into optimizing testicular tissue cryopreservation, advancing strategies for male fertility preservation, and establishing a universal 'cryopreservation-in vitro culture' protocol for future research.

This new Guideline from our Affiliated Society Partner, @cdnfertility, emphasizes a personalized approach to the problem of REPL recognizing an overall promising prognosis and the avoidance of treatment options that have not been shown to be of benefit.

2D-HyFoSy is a reliable technique for Fallopian tube patency testing, helping to establish a diagnostic strategy with high accuracy but minimum invasiveness and limited use of sophisticated technology.

The result of this RCT confirm the previously published evidence that the freeze-all strategy is similar to a fresh transfer strategy and can be applied without compromising reproductive outcomes after blastocyst culture.

The Autumn 2024 edition of RBMO Digest is now available on our website Catch up with our regular round up of specially selected articles from recent issues of the journal Find it on our website now: #RBMOdigest #ClinicalAssistedReproductiveTechnology

This study establishes a murine model illustrating the reversal of infertility associated with ENDO through metformin treatment. This relationship is likely through anti-inflammatory properties manifested in pregnancy.

This new article highlights that a short co-incubation period can be a viable and safe option in IVF, facilitating efficient monitoring of early morphokinetic events without compromising embryo outcomes.

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