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The Journal of Clinical Psychiatry and The Primary Care Companion for CNS Disorders are peer-reviewed leaders informing clinical practice and patient care.
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Pinned Tweet
In patients with depression, psychological pain is a risk factor for suicidal ideation. Those with borderline personality disorder may experience more prominent and temporally unstable psychological pain.
5
9
29
#ProlongedGrief
like what Prince Harry may have experienced after the death of Princess Diana can be a clinically relevant disorder. via
@CenterforPG
35
184
862
#ProlongedGrief
like what Prince Harry may have experienced after the death of Princess Diana can be a clinically relevant disorder. via
@CenterforPG
8
82
281
"We don’t talk enough about
#MentalHealth
in providers. We don’t talk enough about what our actual humanity is." 🎥
@drjessigold
's exclusive responsive
@jakegoodmanmd
's candid
#StopTheStigma
post re: his own mental health care.
#EndTheStigma
#MedTwitter
#MentalHealthMatters
6
33
219
Aaron T Beck, MD was the father of cognitive behavior therapy, founder of
@BeckInstitute
, and a staunch advocate for mental health. He passed today at the age of 100, leaving an indelible and lasting imprint on modern psychiatry and evidence-based treatment.
3
77
208
1
41
179
Clinicians should be flexible and open minded when diagnosing
#ADHD
. It doesn't always look how you think. via
@danidonovan
#theantiplanner
0
20
124
0
32
125
Today is
#NationalSchoolWalkoutDay
. We spoke to a Nashville pediatrician about the impact of
#gunviolence
on an entire generation. via
@everytown
,
@momsdemand
,
@kbgastineau
0
49
93
#Antidepressants
are widely used to treat
#bipolar
illness, though their effectiveness in this disorder has not been established. This randomized, double-blind, placebo-controlled trial assessed the efficacy & safety of
#citalopram
in bipolar
#depression
.
4
46
83
Clozapine is the drug of choice indicated for treatment-resistant
#schizophrenia
, but delays in initiation and underutilization might diminish its effectiveness in clinical practice.
1
24
55
We spoke to a Nashville pediatrician about the impact of
#gunviolence
on an entire generation. via
@everytown
,
@momsdemand
,
@kbgastineau
0
29
51
🧵 ~10k applicants go
#Unmatched
each year in the US'
@NRMP
Medical Residency Match. For many, it’s not the first time. I’m Asim
@awsumpowers
, an
#UnmatchedMD
who applied 3x before successfully matching. This is a POV on that experience.
1/16
#MedEd
#MedTwitter
#MentalHealth
3
12
54
#GunViolence
is "a moment that changes everything" for victims, families and communities, new report finds. via
@everytown
,
@momsdemand
,
@tannuja_roz
8
25
45
CASE REPORT: Young woman who developed acute-onset behavioral changes accompanied by psychosis and catatonia, ultimately diagnosed with ovarian NMDAR-AE.
0
15
50
Benzodiazepine detoxification by rapid taper with a long-acting benzodiazepine and the antiepileptic carbamazepine.
0
17
44
Read this article to learn about a comprehensive model that incorporates multiple
#predictors
of suicidal behavior and that may help identify depressed individuals at high risk of attempting
#suicide
.
0
29
41
#Panic
disorder is associated with greater experience of side effects & worse treatment response in
#depression
.
1
27
35
Evidence has shown that
#bipolar
disorder is often linked to alterations in circadian rhythms. This study looked at the impact of these rhythms on
#suicide
#risk
, as well as the role of hopelessness, in patients with bipolar disorder.
#prevention
1
20
38
The use of antidepressants in the treatment of bipolar disorder can lead to antidepressant-induced mania (AIM)—but not in every case. This article explores the risk factors that might increase the risk of AIM in patients with this disorder.
1
28
38
Benzodiazepine detoxification by rapid taper with a long-acting benzodiazepine and the antiepileptic carbamazepine.
1
8
36
#New
!
#Antipsychotics
can be used in the short-term to manage
#dementia
-related
#psychosis
, but adverse effects can outweigh benefits. Novel antipsychotics or other agents may offer superior efficacy & safety. Explore the evidence in this
#CME
activity.
1
23
37
In this
#CME
Academic Highlights, leading experts in
#MDD
discuss the burden associated with cognitive impairment, effective strategies for assessing
#cognition
, and available pharmacologic and nonpharmacologic treatment options.
1
13
36
If an antidepressant doesn't seem to be working, what is your next move? This meta-analysis compares efficacy and tolerability of increasing antidepressant dose versus continuing the initial dose.
0
23
35
The
#FDA
has now approved intranasal
#esketamine
as augmention in treatment-resistant
#depression
, & recent studies of its efficacy have been encouraging. This meta-analysis synthesizes the evidence to provide an estimate of esketamine’s efficacy in
#MDD
.
1
20
35
Patients stepping down from antidepressants often describe a sensation that feels like a series of electrical shocks that send a shiver through the brain. Psychiatrists shouldn't ignore these "brain zaps".
1
7
32
The use of antidepressants in the treatment of bipolar disorder can lead to antidepressant-induced mania (AIM)—but not in every case. This article explores the risk factors that might increase the risk of AIM in patients with this disorder.
0
30
34
Meta-analysis indicates that donepezil, rivastigmine, and galantamine lessened both delusions and hallucinations in
#Alzheimers
and
#Parkinsons
disease.
0
8
32
This case highlights the importance of recognizing postictal psychosis, a rare complication of chronic
#epilepsy
that remains poorly understood.
0
7
31
If an antidepressant doesn't seem to be working, what is your next move? This meta-analysis compares efficacy and tolerability of increasing antidepressant dose versus continuing the initial dose.
3
25
31
People with
#autism
spectrum disorder have difficulty maintaining eye contact, possibly due to less activity in the dorsal parietal cortex. The more severe the ASD diagnosis, the less this region of the brain lights up.
2
10
34
Once a patient is discharged after a suicide attempt, what can be done to prevent another attempt? This study evaluated a
#suicide
prevention strategy algorithm versus treatment as usual during the 6-month period following a suicide attempt.
0
28
30
Lithium remains the only agent w/ double-blind evidence of efficacy in all 4 phases of
#Bipolar
mood disorder—an epitome of a “mood stabilizer” in the strictest sense. Is it HOPE or HYPE?
#PsychTwitter
#Psychiatry
#Psychopharmacology
1
12
32
36 psychologists published a comment challenging a recent “umbrella review” that disputes the link between serotonin and
#depression
.
1
4
33
Have you read the Clinical & Practical Psychopharmacology series, "Ketamine for Depression"?
Part 1
Part 2
Part 3
Part 4
Part 5
Part 6
0
18
32
#Borderline
personality &
#bipolar
disorders often co-occur, & symptoms overlap. Could they actually be 1 disorder?
0
27
32
After you start patients on antidepressant therapy, how long should it take for them to respond? Read this meta-analysis to find out.
0
27
29
Xanax may be 40% less effective than previously believed. Here's why:
5
1
31
Organic
#psychosis
causing secondary
#schizophrenia
in 25% of a 200-patient cohort who were previously diagnosed w/ primary schizophrenia, a strikingly high rate of misdiagnosis. Read the study, earn
#CME
credit.
#EmergencyMedicine
#PsychTwitter
#MedEd
1
12
31
Lithium remains the only agent w/ double-blind evidence of efficacy in all 4 phases of
#Bipolar
mood disorder—an epitome of a “mood stabilizer” in the strictest sense. Is it HOPE or HYPE?
#PsychTwitter
#Psychiatry
#Psychopharmacology
0
10
32
Clozapine is the drug of choice indicated for treatment-resistant
#schizophrenia
, but delays in initiation and underutilization might diminish its effectiveness in clinical practice.
1
10
32
MDMA shows great potential for accelerating PTSD recovery. Positive phase 3 clinical trial results could lead to FDA approval within a year.
2
11
32
Everybody's talking about this study of the economic burden of treatment resistant depression. This FREE article describes the independent effects of treatment resistance, including work absenteeism, relative to those of depression alone.
0
26
30
Repetitive transcranial magnetic stimulation may be an effective treatment for suicidal ideation in individuals with treatment-resistant
#depression
, suggests new meta analysis findings.
#EndTheStigma
#PsychTwitter
0
7
30
#Lithium
remains the only agent w/ double-blind evidence of efficacy in all 4 phases of
#Bipolar
mood disorder—an epitome of a “mood stabilizer” in the strictest sense. Is it HOPE or HYPE?
#PsychTwitter
#Psychiatry
#Psychopharmacology
1
7
28
CASE REPORT: Young woman who developed acute-onset behavioral changes accompanied by psychosis and catatonia, ultimately diagnosed with ovarian NMDAR-AE.
1
6
28
Read this article to learn about a comprehensive model that incorporates multiple
#predictors
of suicidal behavior and that may help identify depressed individuals at high risk of attempting
#suicide
.
1
19
26
Although
#depression
guidelines discourage monotherapy with
#benzodiazepines
, patients with depression continue to receive benzodiazepine monotherapy. This study evaluates the prevalence and predictors of benzodiazepine in depressed patients.
5
21
31
OLZ/SAM causes significantly less weight gain and minimal metabolic parameter changes compared to olanzapine in patients with
#schizophrenia
. Could be a potential solution for those concerned with medication-induced weight gain.
1
7
30
An
#antidepressant
medication
#switch
often follows a failed initial trial with
#SSRIs
. This study sought to determine the probability & timing of both response & remission & the optimal duration of several second-step antidepressant treatments.
#MDD
1
16
30
#Antidepressants
are effective in preventing
#suicide
, but some antidepressant-treated patients experience increased suicidal ideation. Read this article to learn if clinical features &
#biomarkers
can predict worsened suicidal ideation in these patients.
0
17
26
#Antidepressants
are effective in preventing
#suicide
, but some antidepressant-treated patients experience increased suicidal ideation. Read this article to learn if clinical features and biomarkers can predict worsened suicidal ideation in these patients.
0
8
30
Only 1 out of 3 patients respond to any of the available antipsychotics. A new understanding of how to reduce dopamine release may offer a different treatment approach for patients with
#schizophrenia
.
0
9
28
Evaluating the relationship between ghrelin levels and measures of
#anxiety
in youth with food intake disorders.
0
11
30
There is new research on how to reduce dopamine release in circuits governing psychotic symptoms. These mechanisms offer a different treatment approach for patients with
#schizophrenia
.
1
13
28
Newly FDA-approved LAI may improve adherence and lower chances of relapse in
#schizophrenia
by as much as 80%.
1
12
27
In this small study of young adults at ultrahigh risk for psychosis, researchers showed how exercise affects clinical, social, and cognitive domains as well as changes to brain function regions impacted by the development of
#psychosis
.
0
17
27
Patients with anxious
#depression
tend to have more severe depressive symptoms. Transcranial magnetic stimulation may offer some relief.
0
9
29
This case report serves as a reminder that, in acute medical and surgical settings, more than half of catatonia cases are of neuro-medical, rather than primary psychiatric, origin.
0
6
29
Xanax may be 40% less effective than previously believed. Here's why:
0
8
28
Benzodiazepine detoxification by rapid taper with a long-acting benzodiazepine and the antiepileptic carbamazepine.
0
10
27
Among the most important recent developments in
#ADHD
research is the development of new therapies to better address the needs of individuals living with the condition. Review them here.
1
11
28
After you start patients on antidepressant therapy, how long should it take for them to respond? Click here to find out:
0
19
26
Everybody's talking about this study of the economic burden of treatment resistant depression. This FREE article describes the independent effects of treatment resistance, including work absenteeism, relative to those of depression alone.
1
30
25
#Schizophrenia
is a top 10 cause of global disability. Average potential life lost for individuals with the condition is 28.5 years and costs $92,000 per patient per year.
1
7
28
Read this article to learn about a comprehensive model that incorporates multiple
#predictors
of suicidal behavior and that may help identify depressed individuals at high risk of attempting
#suicide
.
0
17
27
Suicide risk is elevated after discharge from a psychiatric hospital, but does the risk differ among specific psychiatric disorders? This study investigated this question using data from nearly 3 million psychiatric discharges—review the findings here.
1
27
25
The
#FDA
has now approved intranasal
#esketamine
as augmention in treatment-resistant
#depression
, & recent studies of its efficacy have been encouraging. This meta-analysis synthesizes the evidence to provide an estimate of esketamine’s efficacy in
#MDD
.
1
16
28
Neuropsychiatric symptoms such as hallucinations are common in dementia with Lewy bodies (DLB). Although visual hallucinations have received more research attention, auditory hallucinations are important in the diagnosis of DLB. Learn more here:
0
22
26
Clozapine appears to have a protective effect against suicidality in
#schizophrenia
, a unique study using autopsy reports shows.
0
6
26
~800,000 people die by suicide/yr; rate of attempted suicide is ~20x greater*. Update your
#SuicidePrevention
practices w/ the latest research in the Suicide Clinical Resource Center.
#NationalSuicidePreventionMonth
#StopSuicide
#MentalHealthMatters
*WHO
0
16
27
Newly FDA-approved LAI may improve adherence and lower chances of relapse in
#schizophrenia
by as much as 80%.
0
6
25
Antipsychotics result in weight gain along one of three different types of curves, study reveals.
0
6
26
High rates of
#schizophrenia
symptom recurrence after antipsychotic treatment discontinuation are are thought to be due to withdrawal-related phenomena rather than illness recurrence. This post hoc analysis investigates the true reason for symptom return.
1
18
24
Could hypothyroidism and thyroid autoimmunity be linked to depression in adolescents? Read this clinical study of 360 youth with depression and find out.
#thyroid
#depression
#MDD
#adolescents
0
13
27
Newly FDA-approved LAI may improve adherence and lower chances of relapse in
#schizophrenia
by as much as 80%.
2
8
25
Schizophrenia is estimated to reduce life expectancy by 10 to 20 years & suicide is the biggest single cause of premature death that contributes to this shortened life span. Read more to learn about factors associated w/ suicide attempts in these patients.
1
21
26
Xanax may be 40% less effective than previously believed. Here's why:
0
9
24
Treatment for people with
#schizophrenia
is on the cusp of a new era -- more effective medication with fewer side effects.
0
6
26
High rates of
#schizophrenia
symptom recurrence after antipsychotic treatment discontinuation are are thought to be due to withdrawal-related phenomena rather than illness recurrence. This post hoc analysis investigates the true reason for symptom return.
0
18
26
There is new research on how to reduce dopamine release in circuits governing psychotic symptoms. These mechanisms offer a different treatment approach for patients with
#schizophrenia
.
2
8
26
#Autism
can be divided into 4 different subtypes based on behavior, brain function and genetics, a new study finds.
1
6
26
Is it
#bipolar
disorder or major
#depressive
disorder? Perhaps this differential diagnostic tool can help.
1
22
22
In addition to psychosis, depressive symptoms can occur in patients with anti-NMDAR
#encephalopathy
. Review the clinical and pathophysiologic considerations for
#CME
credit.
#MedEd
#PrimaryCare
#NeuroTwitter
0
5
25
A new study linked long-term ADHD medication use to a heightened risk of cardiovascular disease, particularly hypertension and arterial disease.
1
5
26
#Borderline
personality disorder (BPD) is thought to lead to poor response to
#electroconvulsive
therapy (ECT) in
#depressed
patients. This study assessed symptom-severity outcomes among depressed patients with & without comorbid
#BPD
who received
#ECT
.
0
5
25
OLZ/SAM causes significantly less weight gain and minimal metabolic parameter changes compared to olanzapine in patients with
#schizophrenia
. Could be a potential solution for those concerned with medication-induced weight gain.
1
6
24
Newly FDA-approved LAI may improve adherence and lower chances of relapse in
#schizophrenia
by as much as 80%.
0
14
25
#GunViolence
is "a moment that changes everything" for victims, families and communities, new report finds. via
@everytown
,
@momsdemand
,
@tannuja_roz
#WearOrange
2
9
24
This case highlights the importance of recognizing postictal psychosis, a rare complication of chronic
#epilepsy
that remains poorly understood.
0
7
23
How does a patient's resilience level and history of childhood adversity impact his or her health? This study evaluated schizophrenia patients to determine the relationships among mental and physical illness, childhood trauma, and resilience.
1
24
24
Benzodiazepines are used widely for anxiety and insomnia, but what proportion of users are misusing them?
1
15
23
#Depression
can cause notable
#cognitive
deficits. Read this review article to learn about the efficacy of the wakefulness-promoting drug
#modafinil
in the treatment of cognitive impairments associated with major depressive disorder.
1
15
24
How the presentation of behavioral variant frontotemporal
#dementia
differs from those of
#psychiatric
disorders:
#bvFTD
1
17
19
Could
#biomarkers
help predict acute
#suicide
risk? This
#EEG
study investigated whether
#MDD
patients with suicidal attempts or ideation have unique spatial-frequency power characteristics versus MDD patients without suicidal ideation or behavior.
1
18
25
Gender dysphoria, body dysmorphia, and eating disorders are all connected.
0
10
24