Inspiration4's all-civilian spaceflight reveals telomere dynamics and immune adaptations, offering new insights into space travel's impact on human physiology. Groundbreaking data will aid future low Earth orbit (LEO) and deep-space missions!

DeepClinMed-PGM model shows promising results in predicting disease-free survival in breast cancer patients, aiding personalized treatment.

Targeting SQLE in combination with ferroptosis inhibitors may be a promising therapeutic strategy for LUSC.

A Bitot spot. A Bitot spot is a white or gray, frothy lesion that appears on the conjunctiva of the eye. It's a sign of vitamin A deficiency (VAD) and is often associated with dry eyes. Symptoms: Symptoms may include dry, elevated, and lusterless; lesion that looks foamy; be oval, triangular, or irregular in shape; Frequently bilateral; and be accompanied by night blindness. Source: @AllAboutVision

Tteratoma of the pituitary. A teratoma of the pituitary refers to a rare type of brain tumor that originates in the pituitary gland, composed of tissue from all three embryonic germ layers (ectoderm, mesoderm, and endoderm). This can include elements like hair, teeth, and skin, essentially forming a "tumor within a tumor" within the pituitary gland; these are usually classified as mature (benign) teratomas and can be diagnosed through imaging like MRI scans, often requiring surgical removal if causing symptoms like hormonal imbalances or neurological issues. Source: Pituitary Teratoma: A Case Series of Three Cases @NCBI

Specific TP53 mutation combinations can predict HRD status in breast cancer patients, potentially aiding personalized therapy.

NETs formation associated with elevated cir-nDNA release in cancer patients, but cir-mtDNA release appears to be different.

Thalassemia. Thalassemia is an inherited blood disorder that causes your body to have less hemoglobin than normal. Hemoglobin enables red blood cells to carry oxygen. Thalassemia can cause anemia, leaving you fatigued. Symptoms: Thalassemia signs and symptoms can include Fatigue; Weakness; Pale or yellowish skin; Facial bone deformities; Slow growth; Abdominal swelling; and Dark urine. Source: @MayoClinic

Opisthotonos. Opisthotonos is a specific abnormal posture associated with conditions and injuries that impair brain and muscle function. The characteristic symptoms of opisthotonos are a severely arched or curved spine and head and heels that tilt backward. The condition is usually a sign of serious brain conditions, such as meningitis, tetanus, and trauma. Symptoms: Opisthotonos causes the back to become extremely rigid and curved or arched. The heels and head usually bend or flex backward as far as possible in response. If someone is on their back, they will arch upwards, forming an n-shape. In this position, the back usually lifts the back off floor or mattress to some extent. The arms also bend towards the body. In some cases, the head and lower body may be the only part of the body to keep in contact with the ground. Source: @mnt

Recent study identifies plasma eccDNAs as potential biomarkers for early lung cancer diagnosis, revealing promising diagnostic implications.

This study develops a radiomics-based model to differentiate abdominal TB lymphadenopathy from lymphoma using contrast-enhanced CT images.

Zinc deficiency. Zinc is a mineral that the body uses for fighting off infections and producing cells. It’s important for healing injuries and creating DNA, the genetic blueprint in all of the cells. Zinc deficiency is rare but it still occurs in some people. Symptoms: When one is zinc deficient, their body can’t produce healthy, new cells. This leads to symptoms such as unexplained weight loss; wounds that won’t heal; lack of alertness; decreased sense of smell and taste; diarrhea; loss of appetite; and open sores on the skin. Source: @Healthline

Malar rash. A malar rash is a skin rash that appears on the cheeks and bridge of the nose due to certain conditions, such as lupus. People may also call it a “butterfly rash” due to its distinctive butterfly shape. Many health conditions can cause a malar or butterfly rash, including lupus, genetic disorders, bacterial infections, rosacea, and sun exposure. Source: @mnt

High expression of ACE2 receptors in colonic stem cells suggests their role in nutrient absorption and as entry points for SARS-CoV-2.

Serum prealbumin may help assess nutritional and inflammatory states in UC patients, aiding in the prediction of disease severity and readmissions.

Shaken baby syndrome. Shaken baby syndrome is a serious brain injury resulting from forcefully shaking an infant or toddler. It's also known as abusive head trauma, shaken impact syndrome, inflicted head injury or whiplash shaken infant syndrome. Symptoms: Shaken baby syndrome symptoms and signs include Extreme fussiness or irritability; Difficulty staying awake; Breathing problems; Poor eating; Vomiting; Pale or bluish skin; Seizures; Paralysis; and Coma. Source: @MayoClinic

Probably Narrow-angle glaucoma. Narrow-angle glaucoma is a type of glaucoma that occurs when the structure inside the eye that allows fluid to drain normally from the eye (called the drainage angle) becomes restricted. Narrow drainage angles in the eye increases the risk of the drainage angle becoming blocked, resulting in a significant increase in eye pressure and risk of vision loss. Narrow-angle glaucoma symptoms: Symptoms of narrow-angle glaucoma include Sudden severe eye and head pain; The appearance of rainbow-colored circles around bright lights; Hazy or blurred vision; and Sudden loss of vision. Source: @AllAboutVision

Recent studies highlight MSC-EVs' potential in anti-aging therapy through anti-inflammatory effects and wound healing capabilities.

Research highlights HBOT's potential in promoting ulcer healing and influencing gut microbes in IBD patients.

Aortic Aneurysm. An aortic aneurysm is a bulge in the wall of the aorta, the main artery from the heart. Aortic aneurysms form in a weak area in the artery wall. They may rupture (burst) or split (dissect), which can cause life-threatening internal bleeding or block the flow of blood from the heart to various organs. Symptoms of a ruptured aneurysm come on suddenly and can include Dizziness or lightheadedness; Rapid heart rate; and Sudden, severe chest pain, abdominal pain or back pain. Source: @ClevelandClinic

Nasal Septum Deviation. A deviated septum occurs when the nasal septum — the thin wall that separates the right and left nasal passages — is displaced to one side. A deviated septum can be caused by a condition present at birth or an Injury to the nose. In infants, such an injury may occur during childbirth. In children and adults, a wide array of accidents may lead to a nose injury and deviated septum. Trauma to the nose most commonly occurs during contact sports, rough play such as wrestling or automobile accidents. Swelling and irritation of the nasal cavities or sinus cavities because of an infection can further narrow the nasal passage and result in nasal obstruction. Source: @MayoClinic