Sophie Polo Lab
@PoloSophie
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We are based at the Epigenetics and Cell Fate Centre, at the University of Paris Cité, and we investigate chromatin dynamics during DNA damage repair.
Joined October 2020
Friends, Our lab collectively decided to move where the sky is blue. To stay informed about our latest updates (job opportunities, publications, etc.), please follow us on our other platform. See you soon!
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In our new paper, we uncover a damaged chromatin marking mechanism that drives the non-random segregation of UV damage through mitosis. Chromatin alterations impinge on genome stability by controlling DNA damage segregation See Ferrand*, Dabin* et al., Nat Commun 2025.
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We are recruiting a Post doc to work on Epigenetics and Cancer!
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RT @luijsterburglab: Great @EMBO #chromatin2024 workshop in Leiden with @PoloSophie @POberdoerffer @HombreRRo Kyle Miller @FMattiroli @Chap…
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Check out our last review on "New facets in the chromatin-based regulation of genome maintenance"
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RT @ParisEpigenetix: 👏Congratulations Giulia Giacomini and Margherita Mori (@MarghiMori), team @PoloSophie, on obtaining 4th year PhD fello…
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RT @haicovanattikum: You can still register for online attendance of the hybrid EMBO workshop "Chromatin dynamics and nuclear organisation…
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RT @haicovanattikum: Deadline approaching for the EMBO workshop "Chromatin dynamics and nuclear organisation in genome maintenance", June…
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Check out our last paper focusing on altered DNA repair in H3.3 mutant pediatric high-grade glioma! We identified a specific molecular vulnerability with potential for therapeutic targeting. Thank you to our collaborators.
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RT @ParisEpigenetix: ❗️#Chromatin dynamics and nuclear organization in #genome maintenance ❗️ 🗓️June 17–20, 2024 📍Leiden, Netherlands (Hyb…
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RT @ParisEpigenetix: 👏🏻Congratulations Enrico Pobega on your remarkable PhD defense! The work entitled "Exploring the interplay between f…
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RT @ParisEpigenetix: 🤩This is how we celebrated science during the @FeteScience #FDS2023! 👉 With @bocel_m @Val_Dro…
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RT @ParisEpigenetix: 🚨 #JobAlert 🗄️Assistant·e en #gestion administrative pour une unité mixte de recherche (@INSB_CNRS, @univ_paris_cite)…
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Our team is seeking for a post-doc to address the role of SWI/SNF chromatin remodelers in DNA damage response. The position is funded for 2 years through an ANR and can start from October 2023. Contact me directly. Please RT
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Congratulations to Juliette @JujuDabin for being awarded a postdoc fellowship as part of the Marie Skłodowska-Curie Actions of Horizon Europe to study epigenome establishment and maintenance of the inactive X chromosome after DNA double-strand breaks in mammalian cells.
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RT @ParisEpigenetix: 👏Congrats to @JujuDabin, @MarghiMori & @PoloSophie for their new review in Current Opinion in Cell Biology (@scienced…
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We have received €80,000 from SFCE, a joint contribution from Imagine for Margo and Enfants Cancer Santé. This will allow us to validate a new therapeutic target in high-grade pediatric gliomas carrying mutations in histone H3.3. We are very grateful for their support!
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As part of our 10 years of the lab celebration, we had a lot of fun exploring our artistic side of epigenetics with the scientific illustrator @GamartJulie. Some common interest of the lab: chocolate, cycling, climbing, and animals!
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13 Jan 23: We had a wonderful time celebrating 10 years of the lab, how time flies! It was fantastic to see the former and current members of the team. You can only accomplish great things when surrounded by great people. A big thank you to all!
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