Liz Parrish MBA
@ParrishLiz
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Mother, humanitarian, and entrepreneur. Bringing gene therapy to the masses to treat aging-associated non-communicable diseases (AA-NCDs).
Joined August 2012
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@elonmusk
Really? Thanks! We need about $3 billion over the next 5 years to work on genetic cures for diseases that are the biggest killers on the planet today. Can I DM the bank wiring details?
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Was so honored to win the Bacon Prize! I am the first person to receive it without a PhD. So honored. Don’t fight for your limitations, fight for your unlimited future. Thank you
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“The researchers noted that fructose reduces blood flow to the brain’s cerebral cortex involved in self-control, as well as the hippocampus and thalamus.”
#bioviva
#lizparrish
#genetherapy
#biohacking
#biohacker
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I invite you to read BioViva's - nearly 3 years in the making - research paper. We are now designing our pre-clinical work towards human use. Hold onto your hats and prepare to extend your healthy lifespan!
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@elonmusk
If you choose to live today there is no reason, that I see, that you will not choose to live tomorrow or the day after. That includes 50 years from now, that day will be your today. Stop minimizing the meaning of death, deferring it to the future. Today 110,000 people will die,
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Google verified ! Gene therapies are working. I don’t feel a day over 1,500 !
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“Together with the finding that the cytomegalovirus-packaged gene therapies, delivered by injection or intranasally, increased the lifespan of the mice by 41 percent without increasing the cancer risk, the finding is extremely encouraging.”
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"They found that a single administration of the mutant anti-ageing gene halted the decay of heart function in middle aged mice...."
#bioviva
#genetherapy
#lizparrish
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I am raising this account from the dead to try to keep people (young and old) from dying. Here we go!!!
@BioVivaScience
#IHateAging
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Imagine a gene that could boost your IQ by up to 12 points—nearly a full standard deviation.
I took this gene therapy a few years ago.
While it sounds like something out of a sci-fi flick, it’s not.
#bioviva
#genetherapy
#lizparrish
#biohacking
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The recent attacks on the longevity sector were not unexpected. This technology will disrupt the sick care system. We are moving past their shortcomings.
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"The findings show for the first time that contrary to expectations, it is possible to induce heart cell proliferation during advanced states of heart failure and improve heart function, with some beneficial effects on the liver and kidneys' functions."
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"...the treatment reduced LDL cholesterol levels by 70% in just two weeks."
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As far as we know, I am the most genetically modified person on earth.
This is why.
#bioviva
#genetherapy
#lizparrish
#biohacking
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Dying prematurely of disease is the ultimate censorship and likened to a book burning of memories.
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"The Chinese success in restoring hearing to deaf children has galvanized the field globally, leading to potential broader implications of gene therapy in treating other forms of deafness."
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@elonmusk
We are, in a way, reprogramming the human genome to live longer. To do this we need a combination of genes known and still unknown. Please join us.! The future is worth living to see.
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Why longevity? In prioritizing longevity, we are acknowledging the profound impact that extending our lifespans can have on our ability to witness and participate in the unfolding of technological advancements. By prioritizing our health and well-being, we ensure that we have the
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The longevity revolution started a long time ago.
And it's not going to stop.
#longevity
#healthyaging
#antiaging
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BioViva’s mission is to eradicate diseases of aging. Alzheimer’s and other dementias are among the worst. It is an economic and humanitarian crisis, which is why we are building on past successes with a human dementia study.
#bioviva
#Alzheimers
#genetherapy
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Was an honor to watch Professor George Church present BioViva’s work this week.
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Calling all longevity enthusiasts! 🌟
Discover how Klotho could be the key to sharper minds and longer lives in BioViva's latest Medium article!
#bioviva
#klotho
#genetherapy
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Longevity technology isn't just about living longer; it's about revitalizing our world and reimagining the way we live.
Longevity tech will challenge ageism, redefine life stages, and foster abundance for all.
#bioviva
#genetherapy
#lizparrish
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How will gene therapy make interstellar travel a reality?
“By coaxing human cells to express a protein found in tardigrades, researchers gave them radiation resistance. ”
#biotech
#bioviva
#lizparrish
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A beautiful picture for a beautiful topic and a beautiful future.
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This is an exciting journey through the hallmarks of aging, examining how, by better understanding them, we are coming closer to slowing, stalling, or reversing the aging process.
#bioviva
#genetherapy
#longevity
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Could gene therapy cure glaucoma?
Things are looking good! 👀
GENORASIS™ is developing a gene therapy that could restore vision in glaucoma patients.
Learn more about GENORASIS and how you can get involved in our latest newsletter! 🧬
#glaucoma
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"...Baker Heart and Diabetes Institute has found two drugs that can regenerate insulin production in damaged pancreatic cells.
#genetherapy
#diabetes
#type1diabetes
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This gene therapy will be the most expensive drug licensed under the NHS, and of course, it is gene therapy. We can drive the cost down of these therapies by treating the biggest unmet medical need on the planet. Aging.
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Moving forward to longer lives means that humans will need to learn to have more respect for each other. I do not support the sexual harassment or bullying of anyone, at any age or any gender. Power and ego have no place in our future.
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Don’t like new advances in medicine? 🤨 This book is for you! 🤪
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The future belongs to the flexible mind, the kind, the eager to learn, and the person ready to try new things. Don't get stuck in time, be the future!
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"We were excited to discover that telomeres talk to mitochondria…”
#bioviva
#lizparrish
#genetherapy
#biohacking
#biohacker
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Please sign, it's free to do and declares the stakeholders "...immediately expand research on extending healthy human lifespans" and immediately "start targeting the underlying processes of aging". It is now within our reach! and, the journey to clinical development must begin.
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Perhaps one day, thanks to gene therapy, you can be whatever you want to be.
BioViva is working to make this our tomorrow.
#biohacking
#biohacker
#bioviva
#lizparrish
#wellness
#hacking
#biohack
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I have been pushing for this for years, human data is the data that matters to human drug development. Lots to work on in this area. "Congress has responded to the emergence of nonanimal methods and growing public sentiment against animal research."
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"Results, published today (October 18) in Nature, demonstrated the safety and preliminary efficacy of the novel gene therapy approach in high-grade glioma patients..."
#bioviva
#genetherapy
#braincancerawareness
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Do you share the goal of curing age-related diseases? Investor? Come on out, let’s talk gene therapy funding.
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Sickness makes things hard; death makes them impossible.
It’s hard not to deny this, yet we forget that, more than yachts and sports cars, time is the supreme luxury.
Quality time is time we live to the fullest.
#bioviva
#genetherapy
#lizparrish
#biohacking
#biohacker
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Telomeres are protective caps at the ends of chromosomes. Restoring telomeres through telomerase gene therapy is like putting tread on your tires.
#biohacking
#biohacker
#bioviva
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Telomeres are markers of aging and guardians of genomic integrity.
This is why I took gene therapy to extend mine.
#bioviva
#genetherapy
#lizparrish
#biohacking
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"Patients who took part in the first human trial of the therapy experienced a dramatic improvement in their symptoms, and many were able to come off long-term medication and return to life as normal."
#genetherapy
#CRISPR
#raredisease
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We will try to have as many candidate gene therapies to slow or reverse aging-associated noncommunicable diseases by the end of Q 4 2022
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To achieve anything significant, you will be criticized and misunderstood. We must be pillars of strength for the future of medicine and not fall prey to the risk aversion which will kill 41 million people this year. Let us stay on the right side of history.
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BioViva will be open to funding our gene therapy project to defeat aging-related noncommunicable diseases this Nov/Dec. Let's get together to make a better world for our children!
@RichardHeartWin
@richardbranson
@elonmusk
@JeffBezos
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Our first allowed patent. “Methods for Treating or Preventing Age Related Disorders”
Onward!
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“The data are convincing that microglial dysfunction can cause neurodegeneration in the brain....restoring defective microglial function might be a way to fight neurodegeneration in Alzheimer’s disease,”
#bioviva
#genetherapy
#alzheimers
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Wow, an article about gene therapy and my self-experimentation that is accurate! How unusual! Thank you
@NewHumanist
and Peter Ward.
.
@ParrishLiz
created medical history by receiving the most potent dose of gene therapy ever delivered - all in the quest to fight ageing
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Aging is a universal process, but we have yet to master it. As our population ages, the need for solutions that can restore cognitive and physical function will only increase—and so will the cost.
#bioviva
#Alzheimers
#genetherapy
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Personalized medicine is the future, and BioViva’s CMV gene delivery system is paving the way! 🧬
Its massive carrying capacity opens new doors for gene therapy, medicine, and biotech.
#bioviva
#biotech
#genetherapy
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"These breakthrough findings show that a longevity gene from one mammal can be transferred to another species of mammal for lifespan extension."
#bioviva
#lizparrish
#genetherapy
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I am very happy to see so many countries emerging that desire to cure aging. I aim to open the floodgates for ethical gene therapy access - via The Best Choice Medicine Act!
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Ever wonder why longevity research is met with so much fear and anger?
Or why is there so much senseless conflict in the world?
Our latest Medium article answers both of these questions.
#bioviva
#genetherapy
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"Regulators in the U.S. gave the greenlight in 2023 to five gene therapies for rare genetic diseases and in 2024 could see an additional five approved by the FDA, as well as the first-ever approval of adoptive cell therapy for solid tumors..."
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“It replaces the bad gene by delivering millions of healthy copies deep inside the child’s brain. The good copies of the gene are tucked inside a disabled virus which is able to slip into the brain.”
#genetherapy
#aadcdeficiency
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"'If a child cuts off the tip of his finger and they are under the age of seven, it can regrow. We have that capability in us, but we lose it at a certain age. We are now learning how to turn that back on in adults.'"
#disruptaging
#genetherapy
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Longevity is mainstream.
Now the American Heart Association is talking about biological vs. chronological age.
#genetherapy
#longevity
#bioviva
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The investigational program uses CRISPR-Cas9 and two guide RNAs to target three sites within the
#HIV
genome. This is what enables the drug to excise large portions of the HIV genome while minimizing potential viral escape.
#CRISPR
#genetherapy
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Is aging the biggest risk factor for disease? Look at this graph and decide for yourself.
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If anyone is still on Twitter, PLEASE read and sign this petition if you agree with helping people access innovative technology. We only need 200 more signatures and our futures depend upon it!
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I am happy to share a few minutes of film footage from 2015 of the first 2 gene therapies to treat biological aging. I hope that you are as excited as I am about your genetic future.
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One of my favorites! Don’t let fools and fear stop you.
“I must not fear.
Fear is the mind-killer.
Fear is the little-death that brings total obliteration.
I will face my fear.
I will permit it to pass over me and through me.
And when it has gone past I will turn the inner eye
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90% of people with ALS do not qualify for a clinical trial?! An inhumane disease with a 100% death rate in 2-6 years and they do not qualify? Demand change.
#bestchoicemedicine
#als
#aging
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Everyday I believe more and more that the growing list of the hallmarks of aging are the diseases and it would simplify the process of treating biological aging itself.
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We can do this with many other diseases, including the aging process.
"Since then, the accelerated approval pathway has incentivized cancer drug development and hastened patient access to therapies, contributing to a 33% drop in the cancer death rate."
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“We were completely surprised,” says Lars Ittner. “They actually recovered their memory function and their ability to learn returned.
#alzheimers
#dementia
#alzheimersawareness
#caregiver
#dementiaawareness
#genetherapy
#alzheimersassociation
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Longevity Summit Dublin was fantastic!
Longevity research needs Best Choice Medicine.
Please visit the BCM site, read our white paper, and sign the petition (we're so close!).
#patientrights
#longevity
#patientadvocacy
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Overwhelmed today? Just keep going. You are important, don’t forget it.
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@elonmusk
BioViva is preparing our first scientific paper for a better gene therapy delivery system to extend Healthy lifespans on and off Earth. Three years in the making. Come advise?
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Follistatin, a myostatin inhibitor, is about more than muscle mass.
By targeting sarcopenia, it takes on a crucial contributor to frailty and Metabolic Syndrome.
#bioviva
#genetherapy
#lizparrish
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“We wanted to prove beyond a doubt that this would work in different situations, and it resulted in clear improvements in both symptoms and brain pathology..."
#genetherapy
#raredisease
#longevity
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Addressing cellular senescence, inflammation, and oxidative stress through gene therapies like BioViva’s BV-702 could treat, prevent, and potentially reverse Alzheimer's and other forms of dementia.
#bioviva
#genetherapy
#lizparrish
#biohacking
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One year has passed since I took the first gene therapies against biological aging. Happy anniversary team BioViva!
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$15 million dollars for a vanity license plate? We could do two phase-1 clinical trials to treat people with aging-associated diseases for that! 🤨
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Klotho is an incredibly exciting longevity protein.
Read up on what it does and what it can do in our latest Medium story.
#bioviva
#genetherap
#klotho
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I cried when I saw this picture today in
@TheEconomist
. No image has hit me harder in regards to the environment. Living longer lives will give us more time to solve problems, but this problem can't wait. Rethink your food, transportation, and lifestyle. All hands on deck!
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To hell with war! It is time to upgrade our mindsets to happier, healthier, and more productive initiatives.
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From the beginning, BioViva has taken action while others have only talked or waited or talked about waiting.
Why? Because 41 million people will suffer and die this year from aging.
#aging
#seniorcare
#aginggracefully
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“Our research shows that tumour-resident bacteria adapt as the tumour develops to produce what the cancerous cells need, and then feed off some of the nutrients that the tumour produces. "
#fightcancer
#cancer
#cancerawareness
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We have to gain some control over biological aging or face economic implosion.
#bioviva
#genetherapy
#lizparrish
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Dr Wood said that “not everything in nature ages and dies”, adding: “We could reprogram our biology to stop that happening."
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In case you missed it, BioViva is beginning its Series A.
#bioviva
#genetherapy
#lizparrish
#biohacking
#biohacker
#CRISPR
#biohack
#fitness
#healthylifestyle
#motivation
#keto
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Why are villains always the life extensionists in fiction?
From Harry Potter to Indiana Jones, they demonize those seeking longer, healthier lives.
This is BioViva’s take.
#bioviva
#genetherapy
#lizparrish
#biohacking
#biohacker
#CRISPR
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“Two months after treatment [with irisin], the researchers tested the mice’s cognitive performance. The irisin-treated mice performed better on the tests than untreated mice. Treated mice also showed signs of reduced neuroinflammation”
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Biological aging is the loss of function over time.
It is not the same as chronological aging.
Animals like the naked mole rat exhibit negligible senescence.
In other words, they remain youthful, rather than spending the latter half of their lives becoming decrepit.
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Gene therapy is a promising approach for ocular and CNS diseases. Now we can regenerate the damaged optic nerve and provide neuroprotection to patients with
#glaucoma
.
@GENORASIS
is developing genetic treatments to help people regain and maintain their vision and quality of life.
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Time is irreplaceable, which makes it among the world’s most valuable commodities.
Note, however, that it is just that - a commodity.
Youthfulness gives it value. BioViva understands that youth and vitality are inextricably linked.
There is no such thing as “healthy aging.”
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“All four genes are thought to be important for longevity because they address fundamental molecular processes linked to age-related pathologies, like muscle wasting and shortening of the tips of chromosomes, which leads to deterioration of cell function.”
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"The explanation of why physical exercise, the longevity hormone Klotho and blood transfusion from “young” individuals can induce cognitive improvement is linked to the action of a common factor––the secretion of PF4."
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"Rian got gene therapy in 2019, shortly before her 5th birthday. Two months later, she held her head up for the first time."
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"Although this first-in-human trial was very small, it did show a large drop in LDL levels in a few patients.”
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