Mathieu Ferron
@Mathieu_Ferron
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Mathieu Ferron Lab @IRCM_mtl . Prof @umontreal Montreal, Québec. Vitamin K, bone, beta cell, ER stress and diabetes. Conseiller scientifique du CRCQ.🔬Québécois.
Montréal, Québec
Joined November 2019
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Pinned Tweet
Pedro Pascal as histological stains.
A thread.
Methylene Blue
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3K
Mon fils a classé sa récolte de bonbons dans le style "saisie de drogue de la SQ".
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We thank the reviewers for their very helpful suggestions.
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2K
We thank the reviewers for their very helpful suggestions which we now have incorporated in our manuscript.
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Trying to reproduce an experiment based on the material and method section of a paper in Nature.
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Are still other labs around who prepare their own competent bacteria for cloning? We do.
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Est-ce normal au 21e siècle qu'en deuxième année du primaire les enfants aient des cours d'art plastique, d'art dramatique, de culture religieuse, mais aucun cours de science? Cette déconnection entre le cursus scolaire et le monde dans lequel nous vivons est effarante.
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We expressed and purified this recombinant protein in 293 cells this week. We obtained 1 mg of it. It is just crazy to think that this worth >10K$ if you will be buying the same amount from R&D!
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Nature editors desk rejecting the manuscripts submitted during the night.
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A unknown person stole a copy of a new publication of our lab from our lab cork board... good or bad news?
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Just got promoted to Full Research Professor at IRCM!!! Thanks to
@ircm_mtl
and
@med_umontreal
for the support over the past 10 Y. This will not have been possible without all the trainees how worked in the lab, my research associate Julie Lacombe, and more recently
@xqc9gy5mn8
.
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We thank the reviewers for their valuable suggestions.
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When the PI get back to the lab to inspect his old pipetman sets.
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When your PI shows up for 5 minutes in the lab to provide experimental advices.
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We are still looking for at least one PhD student or one postdoctoral fellow to work on fatty liver disease and liver cancer.
@IRSC_CIHR
funded position!
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This morning I was teaching a course at McGill. At the end two students told me "thank you, this was really interesting." It just made my day. 🤩
Students: when you like a lecture, say it to the prof. It matters.
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Currently looking for a professor position. Can be anywhere, as long as it does not snow 6 months a year there.
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Just find out that Pedro Pascal as histological stains was previously and independently described by
@DiegoMoralesN
! So I am sharing his beautiful own data here.
Hey
#PathTwitter
&
#MedTwitter
, check out Pedro Pascal transformed into Pedro Pathcal as different stains & methods in histo/cyto/pathology!
Who said
#Pathology
&
#LabMed
can't be fun? Embrace your inner histo/cyto/pathologist and celebrate
#LabWeek2023
! (4/23 - 4/29) 🧬🔬🎭
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Took me some time, but finally done writing my cover letter for my promotion application:
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@NathanMackBrown
Yes. Me, my wife, my son, my mother, my sister, my father, my brother, the technician in my lab, one of my student... To name a few. None of us got COVID and we are all fully vaccinated.
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My humble opinion, is that this is the result of half-century of peer review...
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Grosse semaine: papier accepté et j'ai eu mon FRQS Sénior! Et demain on fête les 10 ans de notre labo!
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🚨We are looking to recruit PhD student(s) and postdoc fellow, to work on a very interesting project on the role vitamin K-dependent proteins in beta cell and diabetes! Follow up of our recent
@CellReports
paper.
@CIHR_IRSC
funded.
@ircm_mtl
Please RT. More info in the ad 👇👇
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I like to watch this graph and try to imagine what could be my research program if I will be living in early 2000' Canada. This country used to be a wonderful place for biomedical research. Why can't we do better?
@JustinTrudeau
@jwoodgett
@cdavidnaylor
CIHR success rate:
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One of the big mystery of scientific publication
Conducting research: years
Getting the paper reviewed: months
Performing the requested reviews: months to a year
Reviewing the proofs: "Please return all necessary corrections within 24 hours"
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Je suis très honoré de recevoir ce prix de reconnaissance en recherche du Département de Médecine de l'Université de Montréal. Merci à
@ircm_mtl
et
@med_umontreal
pour leur soutien!
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Today is one of those rare "magic scientific" days. We have confirmed the identification a new vitamin K-dependent protein! This is the beginning of a multi years adventure, but this day will be remembered as THE DAY!
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Faire 500 km pour fuir la ville... Mais non, même ici, ils sont là.
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Too much inbreeding in his mouse colonies led to unexpected phenotypes.
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@maisonneuvemag
@ToulasTake
Please explain me why asking immigrants to speak and understand English is more inclusive? You paper is assuming that English is some sort of universal, unifying and pacifying langage. From the point of view of a linguistic minority (French Canadian) this is not true.
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Got some good news today! And consequently there will be at least two fully funded postdoctoral and/or PhD student positions opening in our lab to study the cellular and molecular biology of MASH and HCC. More to come next week when I come back from vacations.
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@MicrobiomDigest
@manuelansede
Wow, I cannot imagine how it is possible to publish 1 paper per week... but 1 every 37 hours!!! 😱
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CIHR, NSERC and SSHRC also need a boost! If the US government can do it, why can't Canada do the same?
@JustinTrudeau
@FP_Champagne
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🚨Please RT! Our lab is recruiting at least one postdoctoral researcher interested in beta cell biology and diabetes!
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Happy to announce that the Ferron Lab obtained a new bridge grant from
@CIHR_ICR
to support our project on NAFLD and liver cancer! This will support the work of
@Shayesteh_Kiani
and hopefully a futur postdoc to be recruited.
L’IRCM souligne avec fierté le succès exceptionnel de ses chercheurs et chercheuses au dernier concours du programme de subventions Projet des Instituts de recherche en santé du Canada.
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St-Elzéar-de-Bonaventure c'est proche du Plateau ou pas?
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Thanks to Diabetes Canada
@DiabetesCanada
for this essential funding which will allow us to pursue our project on osteocalcin as a new therapeutic approach for diabetes.
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@academic_exit
I work in academia (research group leader) and I do give bonus to the people in my lab (staff and trainees) based on performance. I know several colleagues who do the same.
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The good news is that if the lab freezer fails, we can simply put everything outside.
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Thanks to
@CIHR_IRSC
for supporting our project. And a special thank to the reviewers of course!
Congratulations to our researchers, Jennifer Estall (
@dnachicken
),
@FerronMathieu
and
@KmitaMarie
, who stood out in the 2020
@CIHR_IRSC
grant competition to develop highly promising research projects
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@nictitate
We appealed and made the point that you cannot dismiss a manuscript claiming other unpublished data disproved it. The journal maintained its rejection decision.
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Canada needs to massively reinvest in heath research. We are lagging behind other nations.
@JustinTrudeau
@SciChefCan
@KirstyDuncanEN
Canada must make health research a priority, by providing predictable ongoing funding for researchers, says
@HealthCareCan
CEO
@PECloutier
:
#healthresearch
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@Caroline_Bartma
Here another one: I never use bunsen burner when transforming or picking bacteria as long as there is an antibiotic in the media. In 15 years, I never an any issue with my plasmids.
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Ok, I think I need to write down this protocol in Word from scratch.
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Looks like there are two good news in the 2024 Federal Budget. Increased NSERC/CIHR/SSHRC and more money for scholarships/fellowship. Not clear how much more per year this is for CIHR alone (100M$?).
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Congratulations to Dr Kevin Guo from our lab for successfully defending his PhD thesis today!
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An unpopular opinion: being good at the bench is not about having "good hands" or being "gifted". It is about learning the techniques, getting organized, getting focused and not being distracted during the experiments.
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Mount Royal view from our lab meeting room... We are currently accepting postdoct and grad students applications. 😉
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I see lungs.
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Cette PM j'ai pris le REV sur St-Denis; j'ai jamais vu autant de monde en vélo à Montréal. En déposant mon Bixi à la station, un employé de Bixi m'a dit qu'hier ils avaient battu un record historique: 48 000 déplacements Bixi en une journée! 🚲🚲🚲
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Reading the abstract, then looking at the actual results in the paper.
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C'est un honneur d'apparaitre dans le dernier numéro de
@QuebecScience
dans un portrait résumant mon parcourt et nos recherches récentes. Je réponds aussi aux questions de
@SciChefQC
! Nos recherches vous intéressent? Contactez-moi: on recrute!
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Yes, Montreal is a real city! And an amazing place to do a PhD or a post-doc! We are still recruiting. If you are interested in beta-cell, ER biology and metabolic diseases in general, contact me.
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Undergrads students are always baffled when I show them how to balance 19 tubes in a centrifuge without using an extra tube. It does look weird when you look at the rotor, but it is balanced!
@Eppendorf_USA
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@academic_exit
You can also increase your salary by staying in academia. Moving from postdoc to assistant professor is also usually associated with a pretty good increase in salary (and in responsibilities). Plus, you get a retirement plan, which many private companies do not offer.
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I am back to post some BS (from
@trudeau
budget). Looks like our government believes there is no issue with research funding in our Canada. That they have done their job. The end of the 1st sentence is a lie. Also, not a word on the scholarship value who did not changed in 20Y.
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There are ups and downs during grad school. Today is a up for one of our trainees: Big congrats to
@Shayesteh_Kiani
from our lab for being awarded a
@FRQS1
PhD scholarship! 💪
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And the winner of the best question asked at today's "Ask Me Anything sessions" on CIHR Project grant, is (exact wording):
"When will the awful CCV be replaced?"
😂😂😂
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CV statement from rocket scientist: "I provide outstanding mentorship to all the students in my lab"
The lab:
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The findings described in any abstract.
The actual results.
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Update on our preprint: we now have a graphical abstract. "Vitamin K-dependent γ-carboxylation regulates calcium flux and adaptation to metabolic stress in β-cells". More to come...
I am happy to share with you the revised version of our preprint reporting a critical role for vitamin K-dependent carboxylation in the regulation of calcium flux in beta-cells and in their capacity to adapt to metabolic stress! 1/
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Just got the new that I was selected for a talk at a Gordon Conference! 😊 First talk abroad since 2020...
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We just acquired this new essential piece of equipment for the lab.
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