@wwrighID @ID_fellows @TxID_Fellows @JHMed_ID I’m not sure what the right answer is, maybe SHV, but it definitely does not have AmpC.

@madhuacharg @IDdocAkshatha @venkat_id @BradSpellberg @IM_Crit_ @ABsteward @IdVilchez @IDstewardship @AskSubramanian EUCAST recommends 1g. 2g only in meningitis or Pseudomonas.

@Zaydovudine @BradSpellberg @ConnorProsty @DrToddLee @ABsteward @DrEmilyMcD First line therapy in the Netherlands is amoxi + ceftriaxone.

@DrToddLee @TomBoylesID @DrEmilyMcD @ConnorProsty Actually interesting to think about the fact that we hardly ever use two cut offs for a test. Only example I know is GP’s here use finger prick CRP for LRTI. <20: viral, no antibiotics. >100 bacterial, antibiotics. Don’t know any others.

A Longer Duration of Intravenous Antibiotic Treatment for Patients with Early Periprosthetic Joint Infections Is Not Associated with a Lower Failure Rate @ABsteward

@DrToddLee @BradSpellberg @ABsteward @jac_amr Thanks.

@BradSpellberg @ABsteward I see. Makes sense theoretically.

@BradSpellberg @ABsteward @jac_amr @DrToddLee Interesting, thanks, I’ll have a read.

@DrToddLee @BradSpellberg @ABsteward @jac_amr Thank you! Is the +clindamycin in SNAP due to theoretical Eagle effect? Or does that only happen in streptococci?

@BradSpellberg @ABsteward @jac_amr My initial question was about duration. But actually the same question for ID as a whole: How many recent RCT’s showing superiority for a new treatment (regimen)? The only one I know is from 2023 but there was a lot of criticism. @DrToddLee

@BradSpellberg @ABsteward I understand what the point is. But the previous post specifically mentioned absence of evidence for relapse causing resistance. Not a very strong point to support an otherwise good cause.

@LucasBernts @MicroLukas 😎Emblaveo😎

@MicroLukas Why is plazomicin conditional for NDM Enterobacterales? That surprised me.

@DrToddLee @ABsteward @CIDJournal Yes that makes sense.

@DrToddLee @BradSpellberg @ABsteward Working link