Jason Westin, MD FACP
@Lymphoma_Doc
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Professor, Director of Clinical Research, Section Chief Aggressive Lymphoma @MDAndersonNews , past chair of @ASCO government relations committee, Opinions mine
Houston, TX
Joined January 2013
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Proud to share that I have been promoted to Professor at
@MDAndersonNews
. I am profoundly grateful for my patients, team, colleagues, collaborators, and mentors. Looking forward to the next steps to
#EndCancer
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Friendly reminder that words matter:
Patients do not fail therapies, instead therapies fail patients.
#ASH21
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#ASCO19
pro tip: want a copy of a slide from a talk? Don’t hold up your phone for a photo - instead open the iPlanner app, click “interact”, and the slides are shown on your device. Be sure to cite the speaker.
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@DGlaucomflecken
This is not a good post. Thousands of doctors do research via clinical trials and take care of patients and write grants and advocate for their patients. Most of your posts are great, but not this one.
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This incredible reporting should result in Congressional hearings where CEOs of
@Cigna
and other insurance companies should publicly defend this exploitative practice. Sick patients deserve answers from the companies they pay for health insurance.
#FixPriorAuth
Doctors at a major US insurance company deny tens of thousands of claims a month without even looking at patients’ files.
“We literally click & submit,” a former Cigna doctor told
@ProPublica
&
@Capitol_Forum
. “It takes all of 10 seconds to do 50 at a time.”
The inside story 🧵
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Excellent news for our patients: CAR T-cell therapy (axi-cel) is now approved for patients treated in second line for large B-cell lymphoma. My team at
@MDAndersonNews
was honored to play a role in the pivotal result.
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ZUMA-7 is the first trial in nearly 30 years to significantly improve overall survival for patients with relapsed/refractory large B-cell in 2L therapy. Thank you to all the patients who participated in this paradigm shifting trial.
#ASCO23
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My annual
@ASH_hematology
meeting gripes. Add yours
#ASH22
1. CR = complete response. Response is categorical, remission is not.
2. Patients do not “fail therapy”, they are “failed by therapy”.
#lymsm
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Thank you
@RonWyden
&
@MikeCrapo
and
@SenateFinance
for the important hearing today on drug shortages. On behalf of
@ASCO
, I testified “we have life saving drugs, and life threatening shortages”
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Wow! 👀
@GMA
talked about cancer drug shortages this morning, including my testimony for
@ASCO
to
@SenateFinance
. “We have life saving drugs and life threatening shortages” Tell Congress to act: ⬇️
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At
@MDAndersonNews
, we are so fortunate
@ppisters
is leading us to
#endcancer
in the
#COVID19
era.
Starting tomorrow, all people on our main campus will wear a mask.
Given the new data showing up to HALF of COVID infecteds have no symptoms, this will keep our patients safe
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Reminder to speakers at
@icmlugano
: patients don’t “fail therapy”. Words matter, and we need to be careful not to blame our patients when our treatments don’t work. Instead, says patients “were failed by therapy”.
#ICML
#lymsm
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COVID life: when you run into your rockstar wife in the hospital.
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The word genius is used too often, but Dr Freireich was a true genius. Countless lives have been saved by his pioneering work: platelet transfusions, randomized trials, combination therapy, plasmapheresis to name a few. His legacy is immense and enduring
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New: MD Anderson has prohibited work related travel, both foreign and domestic, for at least the next 8 weeks for employees to minimize the risk to our patients.
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Incredible news: We are proud to announce that we have treated 1000 patients with immune effector cell therapy (CAR T-cell) at
@MDAndersonNews
. This is a huge milestone for our patients and their families!
#lymsm
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Very important letter from
@ASH_hematology
leadership on ABIM
#MOC
.
Key points:
-eventually do away with high stakes tests
-remove the clock on LKA to allow discussion instead of rushed guess
-change to 15 LKA questions/quarter
-eliminate CME reporting requirement to ABIM
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Very impressive: ADI-001, CD20 CAR gamma delta T-cells have a high CR rate and low CRS/neurotox in r/r B-cell lymphoma, need more patients but early data look great, presented by Neelapu from
@MDAndersonNews
#ASCO22
#lymsm
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Glad to present “State of the Art: CAR T-cell therapy for B-cell lymphoma” at the
@ESHaematology
. We are now clearly in the CAR T-cell era for patients with B-cell lymphomas: we’ve come so far, but still have much more to do to.
#ESHLymphoid2023
#lymsm
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Happy Thanksgiving!
I’m grateful for family, friends, and to be useful for our patients.
The
@ASCO
election is open, and I’m honored to be a candidate for Board of Directors. Learn more and vote here: 🗳️🍗🗳️
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Congrats to all new
#FASCO
members, including my wife Dr
@ShannonWestin
(on her birthday!!!) 🎉🥳🎂
🎉 Join us in congratulating the following members on earning the Fellow of ASCO (FASCO) distinction this quarter! We're grateful for your extraordinary volunteer service, dedication, and commitment to ASCO. Learn more about the FASCO distinction:
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Excellent news: In the Feb 1
@JCO_ASCO
, our Smart Start trial is now published! Rituximab, Lenalidomide, and Ibrutinib in Patients with newly diagnosed DLBCL. Funded in part by
@ConquerCancerFd
#lymsm
#EndCancer
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Since 1995, the standard for fit patients with DLBCL relapsed after or refractory to initial therapy has been chemo/AutoSCT. 28 years later, we finally have a change to the treatment algorithm.
#lymsm
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Huge news! ZUMA-7 trial shows axi-cel improves overall survival in patients with second-line aggressive lymphoma, compared to chemo/autoSCT. Statistically significant, which should end the “try chemo first” argument. Full data to be presented in the next few months.
#lymsm
#NEWS
: Today, we announced the primary overall survival (OS) analysis results, a key secondary endpoint, of our Phase 3 study of CAR T-cell therapy for initial treatment of relapsed/refractory large B-cell lymphoma.
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Great day of
#ASCOAdvocacy
with the talented volunteers and staff of
@ASCO
Government Relations Committee. Come join us on Capitol Hill April 16-17!
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Today’s a big day:
1. The last day of the
@ASCO
election. I’m honored to be a candidate for the board of directors. Learn more below & please vote!
2. I’m traveling to Washington to testify to
@SenateFinance
tomorrow for
@ASCO
about drug shortages.
#ASCOAdvocacy
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Big news! Our
@LymphomaMyeloma
team at
@MDAndersonNews
has treated our 100th patient with standard of care
#CARTcell
therapy! We are leading the way to bring this new breakthrough to our patients.
#lymsm
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I’m honored to be selected for the
@ASCO
Leadership Development Program to further our mission to
#EndCancer
. The support I’ve received from ASCO &
@ConquerCancerFd
(YIA 12, CDA 15) is incredible and critical to develop a new generation of leaders.
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Great to see that EFS curve on the big plenary screens! A paradigm shifting trial for patients with first relapsed DLBCL.
#ASH21
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On behalf of
@ASCO
, I’m honored to testify to
@SenateFinance
next week regarding the impact of drug shortages on cancer patients. Thank you Senators
@RonWyden
&
@MikeCrapo
for focusing your efforts on this important and unfortunately recurring issue.
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Very important data set presented by Dr Orellana-Noia on lack of benefit of CNS prophylaxis with *EITHER* IV or IT methotrexate. Thought provoking, unclear if we should abandon prophylaxis in high risk patients yet tho. Eagerly anticipating the manuscript.
#ASH20
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It is so gratifying to share the final manuscript with patients who are in a long term remission from a clinical trial we created.
#lymsm
#EndCancer
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Landmark FDA decision: Polatuzab is the first drug approved for patients with newly diagnosed DLBCL since rituximab in 2006. Congrats to all who designed and conducted the Polarix trial, and to the patients who will benefit.
#lymsm
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🚨Huge news! I got a lymphoma question correct on the
@ABIMcert
LKA, end my streak of wrong answers at 3! 🚨 Back to answering questions about cholangiocarcinoma…
#burnout
#timewaste
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This is so important: Prior Authorization is often abused to delay justified treatment/tests.
@ASCO
and others have advocated for change for years. CMS is now finalizing a rule on improvements.
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Congrats to Dr Small, an excellent choice to lead
@ASCO
as the 25-26 President, and to all the newly elected leaders including
@DrChoueiri
,
@JhanelleGray
,
@AbbyRosenbergMD
,
@clarissamathias
,
@CharuAggarwalMD
,
@KimmieNgMD
!
Congratulations to Eric J. Small, MD, FASCO, elected as ASCO President for the 2025-2026 term! He will take office as President-Elect in June. 6 additional members were elected to positions on the ASCO Board of Directors & Nominating Committee. Read more:
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Our review paper on the new standard of care algorithm for second line LBCL treatment is now online! A paradigm shift
@MDAndersonNews
@BloodJournal
#lymsm
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I presented our phI/II trial of lenalidomide, obinutuzumab, CHOP for DLBCL pts: ORR 98%, CRR 90%. Clinical trials are our best weapon
#ASH17
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Wow - time flies! I’m honored to work at the
#1
place to
#EndCancer
:
@MDAndersonNews
. I tell my team “what we do here matters”, and 17 years on its more true each day.
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CAR T-cells are clearly a great advance for patients with DLBCL, but toxicity remains a big problem.
We have a trial open which aims to reduce toxicity with an FDA approved drug - anakinra.
Dr. Strati from
@MDAndersonNews
is leading this key trial.
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At the
@MDAndersonNews
#ASCO19
reception, the Westins ran into our friends the Subbiahs. MD power couples unite!
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Hey
@ASCO
!
The ASCO Election is open, and I am humbled to be a candidate for the Board of Directors.
Click ⬇️ to learn more and to vote! 🗳️
Voting for the ASCO Election is now open. All eligible members are encouraged to cast their ballots.
🗳️ Vote now:
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We were honored to present our
#ASCO_LDP
project on Quality in Cancer Care to the
@ASCO
board. Proud of our team
@VamsiVelcheti
@JYoungPierce
@sandrapdangelo
!
#COVIDTuxedo
of suit top, scrub pants for the Zoom meeting. The future is bright for cancer research.
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Excellent
@ASCO
Government Relations Committee meeting today with agency meetings tomorrow. Advocacy is another way we can serve our patients.
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I was honored to represent
@ASCO
on Capitol Hill where I testified “we have life saving drugs and life threatening shortages”. Please click below to tell Congress to this matters.
Join Dr. Jason Westin
@Lymphoma_Doc
for a
#DayInTheLife
as he testifies before the Senate Finance Committee on the ongoing
#drugshortage
crisis.
We need Congress to act now. Contact your representatives:
#ASCOAdvocacy
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Our manuscript "Circulating Tumor DNA Measurements As Early Outcome Predictors in Diffuse Large B-Cell Lymphoma", led by Drs Kurtz, Scherer, and
@ahaheisalizard
is now online at
@JCO_ASCO
.
@ASCO
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Excited about all the incredible new advances for patients with lymphoma seen at
@icmlugano
? Apply for our Lymphoma Fellowship program at
@MDAndersonNews
. Learn from experts like
@LNastoupilMD
,
@ChrisRFlowersMD
,
@michaelwangmd
,
@sairah__ahmed
,
@DrSwami_Iyer
and more. 👇
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🚨Practice changing trial presented at
#ESMO23
today by the brilliant
@ShannonWestin
: DUO-E: Durvalumab + Carbo/Paclitaxel with Durva +/- Olaparib maintenance in pts with newly diagnosed Endometrial Cancer. Simultaneous publication in
@JCO_ASCO
!
#gynsm
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Hey
@ASCO
members:
The big survey about ABIM MOC was sent to your inbox this morning. Please share and take a minute to provide your feedback on this crucial issue so ASCO can advocate for us.
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My annual complaint at ASH: CR is complete response, it is not complete remission.
Response is categorical, remission is binary.
#ASHFromHome
#ASH20
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Thank you to
@ASH_hematology
for inviting me to tell
#ASH18
about my run for Congress & why it is essential for us to engage in advocacy for our patients.
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Thanks to
@MDAndersonNews
for featuring our Department of Lymphoma & Myeloma contribution to the ZUMA7 clinical trial which showed Axicel was superior to chemo/autoSCT in therapy of patients with early relapsed/refractory DLBCL.
#Teamwork
#lymsm
@NEJM
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The
@MDAndersonNews
Lymphoma team is glad to be part of the excellent
#iwNHL23
meeting. Cutting edge science, latest clinical updates, and robust discussions to improve outcomes for lymphoma patients.
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Our article from
@MDAndersonNews
on
#CARTcell
toxicity & a new management strategy is online at
@NatRevClinOncol
. Please read & RT
New by Sattva Neelapu et al. - 'Chimeric antigen receptor T-cell therapy — assessment and management of toxicities':
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Tough week for the
@MDAndersonNews
family, losing two giants (Drs Mendelsohn and Hong), but we know that after a rainstorm comes a rainbow 🌈. We will continue our fight to
#EndCancer
.
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Thank you to
@asco
for naming me an Advocacy Champion at the
#ASCOAdvocacySUmmit
. I’m proud to fight for our patients, for increased funding for
@NIH
,
@theNCI
, &
#CancerMoonshot
, and more.
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The
#ASH21
Plenary Session starts in a few minutes where
@DrFredLocke
will present the Zuma 7 trial: 24m EFS was 41% for axi-cel vs 16% for chemo/ASCT (HR 0.4) in patients with 2L therapy for DLBCL. A paradigm shift!
#lymsm
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When will our government act? Harris County confirms first Zika-related death in Texas via
@houstonchron
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🙏 to
@ASCO
leadership for conducting a detailed survey re the ABIM MOC.
🗯️: practicing oncologists see very little value in the existing MOC
💡: ASCO’s task force will propose alternative options and seek your feedback.
Advocacy Works!!!
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@DGlaucomflecken
Sometimes IRBs try to take our lunch money too, but I’m glad you recognize your joke was a wrong note. Clinical research is the best weapon we have to make new discoveries so that we can better help our patients.
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Excellent work by
@hjcherng
presenting our trial of obinutuzumab + lenalidomide with CHOP for patients with new DLBCL, supported by a
@ConquerCancerFd
award!
#ASCO22
#lymsm
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The
@ASCO
LDP is awesome, training tomorrow’s leaders to ensure ASCO continues to thrive and help our patients.
@DrSGraff
&
@CharuAggarwalMD
and I were classmates, and are now on the leadership ballot. Encourage your rising star colleagues to apply!
Thanks ASCO and our mentors for the awesome Leadership Development Program!!
Learning and fun together. Thanks to the awesome ASCO staff for making all the arrangements.
#asco
@IshwariaMD
@DrYukselUrun
@SalemGIOncDoc
@KristenCiombor
@PatelOncology
@RamalingamMD
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The
@ASCO
Leadership Development Program is excellent. Early-mid career Oncologists who want to accelerate their career growth should absolutely apply. Plus - you get to know current/future ASCO superstars!
Connect with ASCO members and leadership, learn valuable skills, and take part in developing the future of cancer care. The Leadership Development Program application deadline is approaching! Learn more and apply today.
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Another
#CARTcell
infusion at
@MDAndersonNews
. Our team is leading the way in developing tomorrow’s treatments today with cutting edge clinical trials.
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Throwback: when
@ASCO
LDP met with
@FDAOncology
and
@realrickpazdur
! What an incredible opportunity!
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This: CAR T cell therapy is the most impressive new therapy in B cell cancer. Green=complete response in ALL
#ASCO16
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This is excellent! Dr Bertagnolli will be a superb
@NIH
Director, just as she was great as
@NCIDirector
. As a former
@ASCO
president, we hope she will remain a strong advocate for continued collaboration and will push to bring innovative solutions to American healthcare.
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We are proud to announce the MD Anderson Lymphoma & Myeloma Fellowship program, better than ever. If you are interested, see details here:
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Very important data from Dr Neelapu from
@MDAndersonNews
on relapse after CAR T: CD19 antigen loss is common late, but other B cell antigens remain. Co-targeting may over come escape.
#ASH19
#lymsm
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Hey
@ASCO
! It’s time to vote. The 2023 election is open now! 🗳️🗳️🗳️
I’m honored to be a candidate for Board of Directors.
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Axi-cel has HR 0.27 for EFS, faster recovery of QoL
@DrFredLocke
@mike_dickinson1
@MattUlricksonMD
@DrMiguelPerales
@UF_FarooqMD
@LoriLeslieMD
@Kersten_MJ
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We will present our “Smart Start” trial at
#ASCO19
- rituximab + lenalidomide + ibrutinib alone followed by chemo for newly diagnosed non-GCB DLBCL. ORR 85% prior chemo - allowing for synergy of targeted agents.
#Lymsm
RCHOP + X is not a good trial design in DLBCL: The ROBUST trial, RCHOP vs RCHOP + lenalidomide, did not show superior PFS, details pending.
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Getting ready for the
#ASCOAdvocacySummit
with
@ASCO
and the government relations committee team. We’re on Capitol Hill to fight for our patients and for cancer research. Huge turnout!
0
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Lots of friends at
#ASH18
are asking about my run for Congress. If you’re at the meeting, come hear my talk tomorrow at the
@ASH_hematology
Grassroots Network Lunch!
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The
@ASCO
election is open until Monday. If you haven’t voted yet, it only take a few moments but can have an enormous impact. Learn more about the candidates ⬇️ and 🗳️
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@AaronGoodman33
If they spent 10 minutes asking a few academic doctors why this isn’t already happening, they’d save themselves and their future clients a lot of trouble.
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My setup today for
#ASHFromHome
- attending dual satellite symposia is a plus, but would rather be at
#ASH20
in person.
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Proud of our mentees! Dr
@RaphaelESteiner
and
@JainP_MCL
. Our
@MDAndersonNews
team has 5 presentations this hour at
@icmlugano
, 3 by our rising stars!
#icml
#lymsm
@michaelwangmd
and I are trying to keep up!
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Great to see my friend
@mtmdphd
at the
@ASCO
board of directors meeting. Thank you to
@ConquerCancerFd
for funding our innovative research with a YIA and CDA, an incredible boost for early career oncologists.
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Instead of nihilism about CNS prophylaxis for high risk DLBCL, we should focus on what we use. Methotrexate was created in 1947. Perhaps we could use a targeted therapy instead?
#ASH20
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The view from
#ICML16
has less jet lag, but a smaller lake. Looking forward to seeing friends & colleagues at
#ICML40anniversary
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True hope that cancer will become a manageable disease - soon.
#clinicaltrials
are the key to
#endcancer
.
#CancerFilm
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Dr. Strati from
@MDAndersonNews
shows steroid treatment for axi-cel
#CARTcell
toxicity is associated with inferior outcomes. Is this due to the steroids or due to why steroids needed, the chicken or the egg?
#ASCO20
#lymsm
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