The Kidney Project
@KidneyProject
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A national research and development project creating a small, surgically implanted, and free-standing bioartificial kidney to treat renal failure.
San Francisco, CA
Joined June 2012
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It’s remarkable to think that there have been no major innovations in the world of kidney disease for over 60 years. The Artificial Kidney can offer a life without dialysis. It’s time for an upgrade. Click below to learn more about this device.
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The Kidney Project posted this video last year of one of our researchers explaining the components of the implantable bioartificial kidney.
Share it with your friends and family who would like to learn more about The Kidney Project!
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The implantable bioartificial kidney will require pre-clinical testing before we can begin studies in human patients. The images show the version of the hemofilter device that was tested in the experiments mentioned in the paper.
To learn more, read here:
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Here is a video of one of
#TheKidneyProject
’s researchers explaining the components of the implantable bioartificial kidney.
The prototype is made possible with the help of
@ANSYS
, which allows our researchers to model the complex design requirements of the device.
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Here is a look into Univision visiting The Kidney Project and speaking with Dr. Shuvo Roy. We are so proud of all the progress that has been made, and we look forward to making the implantable bioartificial kidney a reality for the kidney community.
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The Kidney Project team visited Washington DC this week!
Dr. Shuvo Roy and UCSF PhD students spoke with congressional members and presented the demo for our artificial kidney technology.
We have always and will continue to advocate for our
#kidney
community.
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Happy New Year! With every passing year, our goal of completing the first implantable bioartificial kidney becomes closer and closer to fruition. In 2024, The Kidney Project team will continue to advance our research, and we appreciate you joining us for this journey.
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To mimic the human kidney, we advanced the device’s membrane design, use of molecular coatings, and resolved cell sourcing & storage issues. While still in the pre-clinical stage, we’re hopeful that the artificial kidney will improve the lives of kidney patients in the future.
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Building the first implantable bioartificial
#kidney
is hard work, but
#TheKidneyProject
is working hard to ensure it becomes a reality. Thanks to partners like
@ANSYS
, we can model the complex design of the iBAK, which allows us to build prototypes for testing.
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This Thursday is
#WorldKidneyDay
!
#TheKidneyProject
team aims to shift the status quo of
#kidney
care through the development of the implantable bioartificial kidney.
Here’s sneak peek of our prototype.
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In
#TheKidneyProject
lab this week, we are working on the bioreactor component of the implantable bioartificial kidney.
Our scientists are designing different mock flow loop configurations to test the functions of the device.
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An implantable bioartificial
#kidney
means we could eliminate the blood-matching barrier—that means no more waiting around for the perfect donor.
Learn more about
#TheKidneyProject
:
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Today is
#WorldKidneyDay
!
The Kidney Project team is taking part in the
#ShowYourKidneys
challenge. Help us raise awareness of kidney disease and reach our goal of making the implantable bioartificial kidney a reality.
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“The artificial kidney is all about one word: ‘hope.’”
Lizzie Porter (left), a kidney patient and donor to The Kidney Project, received a transplant from her cousin Sara (right), but the idea of an artificial kidney is hope for her if her transplanted kidney should ever fail.
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The average kidney transplant lasts 10-12 years. For young patients, that can mean 3, 4, or 5 transplants in their lifetime. The Implantable Bioartificial Kidney is designed to be a permanent solution to kidney failure.
To learn more, visit
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Help
#TheKidneyProject
reach our goal of creating the first implantable bioartificial
#kidney
by getting the word out about who we are and what we are doing. Share our social media accounts with others and consider donating to our cause.
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Today is World Kidney Day!
The Kidney Project team comes together to
#ShowYourKidneys
, signifying our commitment to create the world’s first implantable bioartificial kidney.
#WorldKidneyDay
#KidneyHealthforAll
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With the implantable bioartificial kidney, patients won’t need to take immune-suppressing drugs.
#TheKidneyProject
team recently proved this in an experiment published in the journal Nature Communications.
Read the
@UCSF
News article here:
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#TheKidneyProject
team is reflecting on our win earlier this month of the Artificial Kidney Prize Phase 2, hosted by KidneyX.
Once again, thank you to our
#kidney
community, donors, and advocates for their support!
Read more here:
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Interested in The Kidney Project? Follow us to stay updated on our current progress!
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Meet Navin Manglani, a donor who supports our research towards an implantable artificial kidney. Navin’s family has a history of polycystic kidney disease but The Kidney Project gives them hope. The Kidney Project thanks Navin and all the supporters who inspire our work!
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#WorldKidneyDay
is on March 14.
Let’s get social! Did you know that you can support us by simply raising awareness of what we do in your personal network?
Use our handles and share our goal to create the world’s first implantable bioartificial kidney.
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Exciting news—The Kidney Project was awarded $1 million from KidneyX for being a winner of the Artificial Kidney Prize Phase 2!
Thank you to our donors & advocates for your support. We couldn't have done it without you!
Read the article:
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In this interview with
@scrippsnews
, The Kidney Project team chats with reporter
@lindseytheis
about the implantable bioartificial kidney and its components.
Watch the video here:
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The photo shows bare silicon wafers, typically used in semiconductor technology. Our researchers have adapted this technology and, through the use of silicon nanotechnology techniques, have created the filters in the hemofilter component of our implantable bioartificial kidney.
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No more bulky dialysis machines—now, that's something to get excited about!
Learn more about
#TheKidneyProject
:
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Therapies for kidney failure are sparse, and the bioartificial kidney will provide a much-needed new treatment option. Thanks to partners like
@ANSYS
for helping us design a device small enough to be implanted, replicating life before kidney disease.
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When will the artificial kidney be ready for human use? Learn more about the artificial kidney and how it will affect someone's quality of life, featuring Dr. Shuvo Roy in collaboration with the National Kidney Foundation.
Listen to the podcast here:
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Have you heard of KidneyX? The Kidney Innovation Accelerator (KidneyX) is a public-private partnership that aims to accelerate innovation in the prevention, diagnosis, and treatment of kidney diseases.
Learn more here:
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As you can see in the CFD images, made using
@ANSYS
, we have explored the geometry of our implantable bioartificial kidney to ensure we limit thrombogenicity as blood passes through it.
The photo demonstrates the improvements made on the device to lower low wall shear stress.
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Our Technical Director, Dr. Shuvo Roy, was featured in
@KidneyPatients
's webinar, where he spoke about the future of kidney transplants and how the implantable bioartificial kidney could change kidney patients’ lives.
Watch the full video here:
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The Kidney Project Director
@shuvoroy
gives Dutch Queen Máxima a demonstration of the implantable bioartificial kidney when she visited
@UCSF
last week.
#kidneydisease
#innovation
#medicaldevices
Photo Credit: Susan Merrell
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#TheKidneyProject
presented four posters at
#KidneyWk
, with topics ranging from implantable devices to hemodialysis.
Click the links to read the abstracts:
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This week,
#TheKidneyProject
researchers are making a cell surface for
#kidney
cells.
They are creating designs that are biocompatible to maintain the stability of the cells, which are implanted behind silicon nanopore membranes.
Learn more here:
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"Every 30 minutes, the kidneys filter all the blood in the body."
This series of articles from Nature highlights chronic
#kidney
disease content, ranging from possible future treatments to current problems faced by kidney patients.
Read the articles:
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Last week, surgeon Dr. Caressa Chen shared the most recent development of the bioartificial kidney at ASN’s Kidney Week. In this presentation, she speaks about the successful integration of the bioreactor and hemofilter within the iBAK prototype.
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To make sure the implantable bioartificial kidney removes urea from blood efficiently, we use computational fluid dynamics (CFD) simulations to optimize its design. This critical work is enabled by tools from one of our partners,
@ANSYS
.
Image made with the ANSYS software.
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What makes The Kidney Project’s implantable bioartificial kidney a better solution than dialysis?
Read more about our project in this interview with Medscape:
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#TheKidneyProject
's Medical Director, Dr. William Fissell, recently wrote about the progression of the implantable bioartificial
#kidney
. You can read the article here:
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We're pleased to announce that the Implantable Bioartificial Kidney (iBAK) was selected as a winner of the
@Kidney_X
Artificial Kidney Prize Competition! Thank you for the support and for helping us reach this milestone on our journey to the ultimate goal.
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#TheKidneyProject
team recently published an article in
@NatureComms
, which proved that kidney cells, housed in an implantable device called a bioreactor, can survive inside the body of pigs and mimic several important functions.
Read here:
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The Kidney Project is beyond excited to announce that our directors,
@shuvoroy
and
@FissellIv
, have received the U.S. Presidential Volunteer Service Award (PVSA) Gold Medal from
@KidneyPatients
!
We will continue to improve the status quo of
#kidney
health care.
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Life on dialysis is tough. While it does keep patients with kidney failure alive, there’s a cost—quality of life. With the implantable bioartificial kidney, dialysis will no longer be required.
Learn more about
#TheKidneyProject
:
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The need for new solutions has prompted researchers from all over the world to work on alternative treatments for
#kidney
disease.
Read the article by
@Pharmacy_Times
, featuring
#TheKidneyProject
’s implantable bioartificial kidney.
Read here:
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Could implantable artificial
#kidneys
end the need for dialysis?
#TheKidneyProject
was featured in a recent
@Nature
article discussing the future of kidney care.
Read the full article here:
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World Kidney Day is on March 9th!
The Kidney Project supports
#WorldKidneyDay
and
#KidneyHealthforAll
, and the completion of our implantable bioartificial
#kidney
will allow kidney patients to be better prepared in case of an emergency.
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Recently,
@Kidney_X
released the prize presentation video of this year’s Phase 1 Artificial Kidney Winners. Click the link below to watch all the recipients including The Kidney Project, featuring Dr. Shuvo Roy. Congratulations to all the participants!
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Happy New Year!
#TheKidneyProject
team wants to take the time to thank our
#kidney
community for all the support we have received. We are looking forward to making more progress on our implantable bioartificial kidney in 2023.
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#TheKidneyProject
’s implantable bioartificial kidney was highlighted in a
@GoHealio
article, which features alternative solutions to treat kidney disease, all of which are advancing in research despite the lack of funding.
Read more here:
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El equipo del Proyecto Riñón-Dr. Shuvo Roy y investigadores-fueron presentados recientemente en Univision!
El reportaje se encuentra aquí:
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#TheKidneyProject
aims to change the status quo. Our goal is to create a surgically implanted, free-standing bioartificial kidney. Click to learn about our progress towards a permanent solution to kidney failure.
TKP:
To give:
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Have you checked out The Kidney Project’s YouTube channel lately? We have released some new videos that talk about the mission of our project and the implantable bioartificial kidney.
Check them out here:
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Here is our technical director, Dr. Shuvo Roy, with his Presidential Volunteer Service Award Gold Medal, awarded by
@KidneyPatients
!
AAKP is one of The Kidney Project’s partners, and they are dedicated to improving the lives and long-term outcomes of
#kidney
patients.
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The Bioartificial Kidney will help patients overcome the burden of dialysis & organ shortage. This video, created for the
@Kidney_X
Artificial Kidney Competition, shows our recent progress. We thank the reviewers and our patient community for your support.
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Kidney failure is one of the leading causes of death, and
#TheKidneyProject
is dedicated to change the statistics by creating an artificial kidney.
In the article, Dr. Shuvo Roy talks about the conception and current progress of the device.
Read here:
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“The Kidney Project offers a glimmer of hope to me [...] I envision a future where I am not bound by dialysis machines, where I can freely embrace my children without the worry of injury.”
Read Ramon's story here:
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Kidney disease is often invisible. Patients can look fine, but others may not know how sick they truly are. That’s why we need the Artificial Kidney. This device can make dialysis, & endlessly waiting for a donor kidney, a thing of the past. Learn more:
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“Will the artificial kidney work as well as a human kidney?”
The artificial kidney is designed to work like the natural kidney, filtering the blood and maintaining the body's fluid balance so that dialysis is not necessary.
Visit our website for more:
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Last week, we talked about our paper on the development of an MCL.
Aside from the physical MCL setup, we also use mathematical models and computational models. With programs like
@ANSYS
, it’s possible for us to simulate how different designs impact fluid dynamics in our device.
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The Kidney Project’s Medical Director Dr. William Fissell spoke at the Rosenblum Lectureship at VUMC last week.
Watch the recording here:
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The average wait time for a donor kidney is 3-5 years. 13 people die each day waiting for a transplant. To learn how the Artificial Kidney will help alleviate the organ shortage, click .
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If you are new to The Kidney Project page, welcome!
The implantable bioartificial kidney is under development, and we have not yet started clinical trials.
If you have any questions about The Kidney Project, please check out our FAQs:
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What’s a mock circulatory loop (MCL)? A mock circulatory loop is a setup that simulates the human circulatory system. We use MCLs to test the fluid dynamics in our implantable bioartificial kidney’s hemofilter.
Read our paper on MCL here:
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The Kidney Project goes LIVE again next Thursday 6/30 at noon PT! Learn about the specific ways the artificial kidney will change day-to-day life for people on dialysis in David Wilson's chat with Dr. William Fissell.
Register here:
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Recently,
@abc7newsbayarea
featured Dr. Shuvo Roy and The Kidney Project team on the latest progress of the implantable bioartificial kidney. Click the link below to watch the interview and learn more about the recent development of our device.
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#TheKidneyProject
Team had a fantastic time at
#KidneyWk2023
! Photos feature UCSF Bioengineering PhD student Alonso Torres, Vanderbilt University Postdoc Kuniko Hunter, and our Technical Director Dr. Shuvo Roy.
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Here is a behind-the-scenes look at some of the filming our team has done this past week, where we answered some of the frequently asked questions from our kidney community.
Stay tuned for more information on our groundbreaking work on the implantable artificial kidney.
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#TheKidneyProject
is working hard to make the implantable bioartificial kidney into reality. In this image,
#ECMO
engineers are using
@ANSYS
to model the transfer of oxygen into the blood flow channel of a previously designed hemofilter device.
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The image shows a streamline analysis of simulated blood particles traveling through the 4-channel device.
This type of analysis is important for ensuring laminar flow through the device and minimal areas of stasis or recirculation.
Modeled using
@ANSYS
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Behind the scenes this week in
#TheKidneyProject
lab, silicon researcher Ben Chui discussed the wafer fabrication process with his fellow team members.
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Have you had the chance to watch
#TheKidneyProject
’s YouTube Q & A Lives?
Here is a snippet from our September 2022 Live featuring Dr. Shuvo Roy, in which he discusses the features of the implantable bioartificial kidney.
Watch the videos here:
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Today is
#WorldKidneyDay
! The Kidney Project would like to share an update on the implantable bioartificial kidney. Click below to watch our update video, or read our update on our Facebook page.
Video:
Facebook/To give:
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Thank you to the John and Marcia Goldman Foundation for their recent $1 million grant to The Kidney Project which will support the development of the bioreactor, a key component of the implantable bioartificial
#kidney
. Click the link to learn more.
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Enzymes from cells naturally degrade proteins in tissues and can cause problems in artificial organs. Click below for Drs. Fissell & Roy’s recent research on undegradable cell scaffolds, which can improve the longevity of implantable bioartificial organs.
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This year,
#WorldKidneyDay
is on March 9th.
Let's raise awareness around the world about the importance of our
#kidneys
! Celebrate the 2023
#WorldKidneyDay
campaign under the theme of
#KidneyHealthforAll
.
Visit the
@worldkidneyday
website:
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This device will be a permanent solution to kidney failure & our team is pushing to bring it to reality. Our current research suggests it will operate for many years without failing.
Please share to help bring this device to those in need.
To Gift:
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For immunocompromised people, navigating life can be scary, especially in the COVID era. Because it remains isolated from the immune system, the Artificial Kidney will not require immunosuppressive drugs. Click the link to learn more: .
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37
Have you visited our website lately?
#TheKidneyProject
’s FAQs page is now updated! Find the answers to all your pressing questions, such as how the implantable bioartificial
#kidney
works and the timeline to clinical trials.
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We’re using silicon nanopore membranes to create an implanted device that performs the kidney’s most vital filtration functions. Thanks to partners like
@coventorinc
, we can apply advanced
#software
to solve modeling,
#design
, and integration challenges more efficiently.
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9
35
Next Thursday, The Kidney Project will go live with AAKP (
@kidneypatients
) to discuss the role of partnerships and advocacy in making the implantable artificial kidney a reality for patients. Register today to watch “The Decade of the Kidney” on YouTube.
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Last month, The Kidney Project’s Technical Director attended the 5th Annual Global Summit on Kidney Disease Innovation, in which he was featured as a panelist for a session on the “Pathway to Artificial Implantable Organs: Industry Commitment to Innovation.”
Read more below:
Dr. Shuvo Roy joins the Global Summit to provide information and updates on the
@KidneyProject
, a freestanding bioartificial kidney project! Conversations around artificial implantable organs are happening NOW!
REGISTER TO JOIN ➡️
#GlobalKidney2023
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NBC Bay Area recently featured our technical director, Dr. Shuvo Roy, in a morning news segment.
Watch the video here:
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Recently, The Kidney Project submitted our entry to KidneyX for the Artificial Kidney Prize. Thanks to
@ANSYS
, who helped us engineer our device, we are confident that our submission represents a
breakthrough in the treatment of kidney failure.
#Ansys
#KidneyX
#TheKidneyProject
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The Kidney Project is heartbroken by the loss of kidney patient advocate Nieltje Gedney last week.
As Executive Director of Home Dialyzors United, she fervently pushed for policies & innovations to benefit the kidney community.
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We are now on Instagram
@ArtificialKidney
Let's get the word out. We are creating the world's first implantable bioartificial kidney.
Join us:
Facebook:
Instagram:
Give a gift:
#TKP
#KidneyDisease
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Warm wishes from
#TheKidneyProject
team to you and your family! We hope your holidays are filled with joy & love.
#kidneydisease
#dialysis
#kidneytransplant
#transplant
#medicine
#technology
#innovation
#techtrends
#technews
#techlife
#holidays
#happyholidays
#celebration
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The bioreactor’s design is reliant on an optimized blood flow path. Our work has been made possible thanks to the help of computational fluid dynamics (CFD), provided through our partner in fluid dynamics simulation,
@ANSYS
.
Read more here:
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31
Our friends over at
@mantis_bbq
have released a line of BBQ sauces in support of
#TheKidneyProject
! 10% of all sales will fund our progress towards clinical trials of the implantable bioartificial
#kidney
.
Visit
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Meet Carlo Tateo. Carlo supports our work as a donor and recently traveled from Italy to visit The Kidney Project. Click the link below to read his story.
Facebook:
Like/Share to promote The Kidney Project
#TheKidneyProject
#ThankYouCarlo
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In
#TheKidneyProject
's February Live Q&A, Dr. Shuvo Roy sits down with
@jbbayton
, Director of Strategic Planning at Home Dialyzors United and a passionate patient advocate for the kidney community for two decades.
Register here:
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On Monday, Jan. 31 at 4pm PST, Dr. Shuvo Roy will be Live on YouTube for our new monthly Q&A series. Register at to hear the latest on the implantable bioartificial kidney and get your questions answered.
YouTube:
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Thanks to partners like
@ANSYSinc
, we can prototype complex designs of the implantable bioartificial kidney (iBAK). Our latest silicon nanopore membranes enhance the hemofilter’s porosity and ensure a safe level of stress distribution.
#ansys
#innovation
#kidneyhealth
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27
Help
#TheKidneyProject
bring HOPE to kidney patients! Your gift on
#GivingTuesday
directly supports The Kidney Project’s work to create the first implantable bioartificial kidney.
GIVE TODAY at
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30
Research towards cell optimization is key for the artificial kidney’s development. Please support our work as we continue to create a new universal treatment for kidney patients.
New Research:
VUMC:
UCSF:
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#TheKidneyProject
's work isn’t possible without our various partners & sponsors.
Thank you to
@ASNKidney
,
@KidneyPatients
,
@hdunews
,
@ANSYS
, and many more for their support!
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5
30
During
@ASNKidney
's
#KidneyWk
, The Kidney Project team met up with members of
@KidneyPatients
, including
@knightra
. We care about our community, and we want to make sure we engage with our patient advocates!
Learn more about AAKP here:
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Our Medical Director, Dr. William Fissell, was featured last year in a three-part series where he discusses the progress our team is making as the bioartificial organ moves toward the manufacturing stage.
Read the articles for more information:
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