JelenaBezbradicaLab
@JelenaLab
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Many cytosolic proteins are released by cell death. Why do some become autoantigens? In a team work led by Esther Jones and @LD53073604, we explore the story of a common autoantigen, TRIM21
Autoantigen TRIM21 (Ro52) assembles pro-inflammatory immune complexes following lytic cell death #biorxiv_immuno
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RT @miner_lab: Our latest work on the role of STING in autoinflammation. STING proton channel activity influences Golgi transit & secretion…
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RT @JExpMed: Lee, Benoist et al. @harvardmed profiled all immunologic cell types by RNAseq after systemic exposure to IL1β, IL6, and TNFα,…
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RT @sethmasters: A large dataset we hope is helpful for patients who may have CAPS, an #autoinflammatory condition associated with gene var…
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RT @Synth_Immune: Now we know a major function of #Granzyme K is #extracellular to activate the #complement cascade. Out now @Nature from…
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RT @yeelondra: We were thrilled to welcome Ada H. Liebenau at our event, where she provided a deep dive into inflammasome signaling. Her di…
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RT @AlexandraBoegli: Happy to announce the first preprint of my PhD 🥳 We show that the inflammasome receptor NLRP6 is activated by sterile…
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RT @FedericoDePont1: 🔥Thrilled to announce that our latest work on the functional heterogeneity of hepatic macrophages in tissue damage and…
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RT @JExpMed: Gomez-Diaz, @v_hornung et al @LMU_Muenchen show that mice lacking RNase T2 display an inflammatory phenotype in a TLR13-depend…
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RT @_kaiwenchen: Thrilled to start 2025 with our latest findings! @fallfelfallen Yersinia invades macrophage cytosol to activate caspase-11…
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RT @ImmunityCP: Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasom…
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Thank you @FelixRandow for visiting @KirOxford and discussing different layers of cell autonomous innate immunity. Super inspiring seminar!
Thankyou to Dr Felix Randow for speaking to us today about how cells use autophagy to defend their cytosol against pathogens, and how some bacteria can counteract antibacterial autophagy.
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RT @inflammasomelab: Have you ever wondered whether pyroptotic corpses have functions beyond the grave? We made the surprising discovery th…
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RT @broz_lab: Did you know that NINJ1 exists as an autoinhibited dimer in the PM of cells? In a @NatureNV @EBernard1993 and Petr describe n…
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RT @AusCellDeathSoc: 🔥 An absolutely remarkable publication by our 2024 ACDS Prize for Outstanding ECR winner, @CarolineLHolley, @inflammas…
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RT @TorresVJ_Lab: 1/8 Publication Alert! Delighted to share the publication of a collaboration by Gerben Marsman (@zychlinsky lab @mpiib_b…
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RT @anandparas: Join us on 21st November for another exciting InflammaZoom session, where I'll be hosting Serge Mostowy (@MostowyLab) and @…
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