insitro
@insitro
Followers
6,118
Following
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Media
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Making medicines differently to bring better drugs faster to the patients who benefit most with ML and data at scale.
South San Francisco, CA
Joined May 2018
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insitro is proud to be working with
@EliLillyandCo
to accelerate insitro’s discoveries to the clinic by leveraging Lilly’s proprietary GalNAc delivery technology and expertise in biologics design. insitro retains full global rights and Lilly is eligible to receive potential
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19
We're thrilled to announce our $400M Series C financing, which will greatly enable us to continue advancing our vision to reshape the discovery and development of transformative medicines by leveraging
#machinelearning
and biology and chemistry at scale.
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We're excited to announce the open sourcing of redun, an expressive, efficient, and easy-to-use workflow framework designed to deal with complex, rapidly evolving scientific workflows spanning multiple data types. Read more here:
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We are excited to announce the closing of our $143 million Series B financing, supporting expansion of our
#machinelearning
and data generation capabilities to enable advancement of therapies toward the clinic.
#ML4Medicines
Read more here:
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We're pleased to share a look into part of our biology discovery platform, CellPaint-POSH, an ML-enabled high-content pooled optical screening system. Our research shows pooled genetic screening w/ cellular imaging can enhance gene function understanding.
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Congratulations to our Founder & CEO
@DaphneKoller
for receiving the Allen Newell Award for seminal contributions to machine learning & probabilistic models, the application of these techniques to biology & human health, & for contributions to democratizing education
ACM-AAAI Allen Newell Award recipient
@DaphneKoller
has been instrumental in using
#MachineLearning
as a tool to advance biology and medicine. As a co-founder of
@coursera
, she has also made great contributions to democratizing education:
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(1/3) insitro is excited to share our paper “EmbedGEM: A Framework to Evaluate the Utility of Embeddings for Genetic Discovery,” focusing on assessing the use of ML-derived embeddings for genetic discovery using heritability & relevance to specific diseases.
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insitro welcomes
@SerafimBatz
as Chief Data Officer. His expertise in ML and computational genomics will accelerate our progress towards our mission of leading the way to better medicines through predictive models that integrate ML and biology at scale.
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Tomorrow, our CEO & founder
@DaphneKoller
takes the virtual
@TechCrunch
Disrupt stage as she talks about our mission of transforming pharma R&D through
#machinelearning
and data at scale. Watch the livestream here:
#TCDisrupt
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We’re very proud to share that insitro CEO & Founder
@DaphneKoller
has been elected to the National Academy of Sciences in recognition of her pioneering contributions to Machine Learning. Congratulations to Daphne and her distinguished peers for this prestigious recognition!
#ML
We are thrilled to announce the election of 120 members and 23 international members to the National Academy of Sciences in recognition of their distinguished and continued achievements in original research.
Congratulations to our new
#NASmembers
!
#NAS160
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If you missed our CEO and founder
@DaphneKoller
's talk at
@TechCrunch
Disrupt yesterday, hear why she says digital biology is the next big technological revolution and how insitro is using it to shift the trajectory of drug discovery.
#TCDisrupt
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We're excited to announce our acquisition of Haystack Sciences, leveraging their leading-edge DEL technology, and advancing our aim to become a fully integrated drug discovery and development company. Read the release:
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Our CEO
@DaphneKoller
spoke with
@RuthReader
to discuss what's next following our Series B and how
#machinelearning
could be the key to cracking the code to drug development. Read below!
#ML4Medicines
Combining AI and biology could solve drug discovery’s biggest problems
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We're proud to share that our CEO and founder
@DaphneKoller
is the recipient of this year's
#IEECS
Women of ENIAC Computer Pioneer Award. Congratulations, Daphne! 🎉
Congrats to Daphne Koller and her achievement of the 2022
#IEEECS
Women of ENIAC Computer Pioneer Award for “contributions to representation, inference, and learning in probabilistic models with applications to computational biology and human health.”
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We presented at the virtual
#EASL20
conference, sharing findings from our study with
@GileadSciences
and other university partners which utilized
#machinelearning
to populate imaging data that quantified the histological features of NASH. View it here:
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We're thrilled to announce our collaboration with
@GenomicsEngland
to bring our
#MachineLearning
-powered embedding search capabilities to their multimodal phenotypic and genetic database to create better medicines for patients in need.
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4
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Thank you to
@a16z
for hosting yesterday’s AI Revolution event. During their fireside chat, insitro CEO & founder
@DaphneKoller
& a16z's
@vijaypande
discussed how AI/ML combined with high-quality datasets could provide novel therapeutic insights & transform drug discovery.
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We’re excited to share
@matthewherper
’s new story in
@statnews
, which spotlights 3 new research papers posted online describing exciting developments emerging from our
#ML
platform across our core therapeutic areas. Read more below.
#JPM24
Biotech founded by Daphne Koller makes stir on eve of JPM conference with new papers on drugs for cancer, ALS, liver disease; poaches new CMO from Pfizer.
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Big news today! insitro has appointed industry-leading scientist & drug hunter Philip Tagari as CSO. We’re very excited for Philip to partner with our founder & CEO
@DaphneKoller
and our world-class team as we transform drug discovery & development.
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We're excited to hear our CEO and founder
@DaphneKoller
deliver the keynote address at
#ICML21
today and share our exciting new work in molecular design. To learn more, visit:
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Today our CEO and founder
@DaphneKoller
will keynote
#BMVC2021
and Hervé will Spotlight at
#MLCB2021
. They will share new data suggesting
#MachineLearning
enables longitudinal phenotyping in live cells. Stream:
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Our CEO and founder
@DaphneKoller
spoke with
@ldtimmerman
for The Long Run podcast this week, discussing her journey to tackling
#machinelearning
for drug discovery. Listen below! ⬇️
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We’re 5,000 followers strong! Thanks for joining us as we journey to transform
#drugdiscovery
through
#machinelearning
and data at scale to more efficiently get new medicines to patients in need.
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As a leading company at the intersection of
#machinelearning
and data generation at scale, we are looking forward to welcoming the Haystack team and working together to create the next-generation therapeutics discovery platform.
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1/7 As published today in AJHG, insitro is excited to share new research in gene-based rare-variant association testing to detect genes with *allelic series*, which helps accelerate efforts to discover new medicines for the patients who can benefit most.
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9
21
Our CEO and founder
@DaphneKoller
joined fellow visionaries and leaders at the
@wef
Davos 2024 Annual Meeting this week, discussing the expanding universe of generative
#AI
models. Watch the full panel below.
#WEF24
@aidangomez
.
@DaphneKoller
discusses building computers that are capable of finding patterns to address societal problems in a way that people can’t do on their own.
#wef24
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#AI
in drug discovery has incredible potential, but it remains hard and some of the hype may not be grounded in reality. Our CEO and founder
@DaphneKoller
spoke with
@MaxGelman
about why she believes the industry needs to calibrate people's expectations with what's possible.
Despite a flood of companies entering the AI space, the field has little hard data to show for itself, at least as far as the public can see. And that begs the question: How much of the “AI revolution” is hype, and how much is grounded in reality?
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We’re excited to hear insitro CEO & founder,
@DaphneKoller
share her perspective with entrepreneurs at
@StartupGrind
. She will discuss how recent advancements in
#ML
represent new opportunities to solve critical challenges in drug discovery & development.
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We are excited to welcome
@martha_rook
,
@Tkaraletsos
, Ellen Berg and Jevan Soo Lenox to our team! Learn more about how their collective expertise will make an impact at insitro here:
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Check out our Founder & CEO
@DaphneKoller
in a recent interview with Lex Fridman that combines machine learning and biomedicine and her appearance in the May/June issue of
@Divinaction
magazine
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Check it out! Our founder and CEO
@DaphneKoller
joined The Data Pulse podcast to talk about building a culture for data-first drug discovery. Listen below. ⬇️
I had a blast chatting with
@DaphneKoller
of
@insitro
about the importance of building a “bilingual” culture when innovating at the intersection of data science + biomedicine. Listen to our conversation to hear insights from this trailblazer!
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Exciting coverage of our founder & CEO
@DaphneKoller
and our work at
@insitro
in the latest issue of
@forbes
Check out the full piece below.
#ML4Medicines
#insitro
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Thanks to
@TwoSigmaVC
for featuring insitro at their AI conference in NYC this week. In a chat with
@DusanPerovic
, our CEO
@DaphneKoller
shared how we use ML & data at scale to advance our mission to bring better drugs faster to patients who can benefit most.
#AI
#ML
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Great to have our Founder & CEO
@DaphneKoller
at the
#STATsummit
on hype vs. reality of AI in Pharma R&D and Pharma’s evolution into a data science with Aviv Regev, Hal Barron, and
@DamianGarde
#insitro
#ML4Medicines
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We're delighted to welcome Dr. Roger Perlmutter, President of Merck Research Labs, to our board. His extensive experience and deep knowledge of biopharma R&D will be invaluable as we begin building our internal therapeutics pipeline. Read more:
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We're thrilled to launch a new , an immersive portal into our platform, pipeline, science, technology & culture – the intersection of which makes us a company like no other! Check out our teaser video & bookmark us to follow our science, news & progress.
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Founder and CEO
@DaphneKoller
welcomed
@BiotechTVHQ
’s
@bradloncar
to insitro and gave an inside look at how we are building a different kind of drug company through the power of
#machinelearning
and data at scale. Check out the full interview below.
Bright Minds: As biotech gravitates to machine learning and AI,
@insitro
founder
@DaphneKoller
shares her experience of working this way since 2018.
Full video:
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insitro is excited to launch the new and improved , bringing you greater insight into our mission, our people, and our approach to transforming
#drugdiscovery
.
#ML4Medicines
#MachineLearning
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"Our lives begin to end the day we become silent about things that matter.” -MLK
At
@insitro
we believe that we must all stand up against injustice, racism and violence. Read the message below by our CEO
@DaphneKoller
on how we can
#changethetrajectory
.
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Congrats to our CEO and founder
@DaphneKoller
for making
@Forbes
list of 8 women leading the field of
#AI
and shaping it for future generations!
Thanks
@_RobToews
for including me in your
@Forbes
article and letting me talk about our work about our work at
@insitro
on using
#ML
for drug discovery. Honored to be included with a group of such amazing women scientists.
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insitro is proud to be on the
#XB100
list of 100 private deep tech companies who are commercializing scientific research into deep technology to make a significant impact on the world. Thank you to
@BessemerVP
&
@XPRIZE
for the honor.
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Thanks to the AWS team for featuring Matt Rasmussen
(
@mattrasmus
), our VP Software Engineering, in today's HPC blog. We are grateful for the opportunity to continue sharing our excitement about the redun workflow engine we open sourced last year.
I have always enjoyed my conversations with the smart folks at
@insitro
. In this post,
@mattrasmus
talks about their data science workflows that run on AWS Batch.
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Congratulations to our amazing CFO/CBO
@mmrozenman
for being a part of the
#20under40
list!
“Mary is like a force of nature: You do not want to get in her way, but she does it in the nicest way,”
@DaphneKoller
on Mary Rozenman
@insitro
. “You find yourself doing what she wants, and you think it was your idea.”
#20under40
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Thank you to
@JohnCendpts
and the team at
@endpts
for including insitro in the
#eleven20
list! We are honored to be included, along with some of the other most promising private companies in biotech as we work to transform drug discovery and development.
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Participating in
#NeurIPS2022
? Join insitro senior machine learning scientist Srinivasan Sivanandan’s virtual presentation tomorrow for a deep dive on using
#MachineLearning
to analyze and learn from image-based pooled CRISPR knock-out screens.
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Are you looking to push the boundaries? Come join us as we leverage
#machinelearning
and
#AI
to create more predictive insights and new medicines through biology and chemistry data at scale. Check out these openings and others below!
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Thanks to
@AmerChemSociety
for featuring insitro scientist Madeleine Kieffer's talk on our DEL-ML Platform at
#ACS2023
. Integrating insitro’s DNA-Encoded Libraries with our advanced
#ML
is helping accelerate our drug discovery & development efforts with chemical data at scale.
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No, it's not opposite day at insitro! It's the G&A and Executive Leadership automation tour courtesy of our amazing process engineering team! Thank you to our PE and imaging
#MachineLearning
colleagues for giving us a peek into the new labs coming online later this year.
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New insitro research published by
@AmerChemSociety
introduces DEL-Compose. Our model uses synthons to efficiently represent billions of DNA-encoded library (DEL) molecules, overcoming modeling challenges to enhance prediction & accelerate drug discovery.
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Happy anniversary, insitro! We are grateful for our investors, partners and, most importantly, our employees who have been with us every step of the way on our journey to transform drug discovery. 🎉
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Passionate about
#machinelearning
& human health? At insitro, we're pioneering the use of ML and data at scale to accelerate the drug discovery & development process. Join us in working to transform medicine for patients in need: .
#AI
#ML
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insitro CEO & founder
@DaphneKoller
will present at the J.P. Morgan Healthcare Conference on Monday, Jan. 9, at 9 am PT in the Golden Gate Ballroom at Westin St. Francis in SF. Join us for the latest from our journey to transform drug discovery & development with
#ML
.
#JPM2023
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Heading to
#SciPy2023
? Make sure to check out insitro’s Head of Computational Biology, Angela Pisco, for the Thursday keynote! She’ll be discussing how we can leverage vast biomedical datasets to provide insights for the development of better medicines. .
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Don't miss insitro scientist Max Salick’s Keystone Symposia presentation on Feb. 7. Max will explain how several technologies – including iPSCs, gene editing, & insitro's advanced genetic screening platform – led to promising new drug discovery targets.
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Congrats to
@NEJM
for launching NEJM-AI, focused on clinical evidence at the intersection of science, health & AI. We're proud that insitro CEO & founder
@DaphneKoller
is among the experts on NEJM-AI's editorial board. We can't wait to read the first, trailblazing issue!
Coming soon: NEJM AI, a new journal from NEJM Group.
NEJM AI aims to identify and evaluate state-of-the-art applications of artificial intelligence to clinical medicine. Learn more about the new journal:
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We are thrilled to announce that Matt Rasmussen has joined insitro as Vice President of Data Engineering and Duane Valz has joined as General Counsel. Welcome,
@mattrasmus
and Duane!
#insitro
#ML4Medicine
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insitro is transforming
#drugdiscovery
. “We use machine learning to build a compass that, when you hit these intersection points, can tell us which paths to pursue,” said insitro CEO & founder
@DaphneKoller
in a
@Forbes
conversation with Steve
@vassallo
.
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Our Founder & CEO
@DaphneKoller
will speak at
#WiDS2020
at
@Stanford
on March 2, a one-day tech conference where you will learn how women in leading-edge organizations leverage data science for success. Register for WiDS Stanford:
@WiDS_Conference
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Our CEO and founder
@DaphneKoller
joined the
@AIHealthPodcast
to describe insitro's approach to rethinking drug discovery using
#machinelearning
and data at scale, and the broader trend of digital biology. Listen below! ⬇️
Our latest episode is with
@DaphneKoller
, CEO and Founder of
@insitro
, a machine-learning enabled drug discovery company.
Dr. Koller speaks about how insitro uses AI and induced pluripotent stem cells to make drug discovery more efficient and successful.
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Thank you,
@AWS
, for hosting our Founder & CEO
@DaphneKoller
to discuss the amazing work here at insitro transforming drug development
@AWSreInvent2019
#insitro
#ML4Medicines
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New Research Alert: insitro is using machine learning to better understand the complexities of cancer. Read our recently published paper to learn about how we leverage ML & patient data to identify novel biomarkers & inform therapeutic interventions.
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We are excited to announce the assembly of our Scientific Advisory Board, who will partner closely with our team to help drive our technology and drug development programs forward. Read more:
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Pleased to contribute to EMBL-EBI's precision medicine workshop, where insitro ML scientist Chris Probert shared how insitro’s ML models use high-content molecular data to predict patient outcomes & identify disease drivers. To join our mission:
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Thank you
@BusinessInsider
and
@rtnarch
for including us! We're on a mission to create better medicines through predictive models, created by
#MachinelLearning
and biology at scale, and are proud of the great work we are doing for the future of patients.
9 top Bay Area biotechs that VCs say are poised to take off in the next year
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It's go time!
#inVivoWeek2023
officially started today at insitro with an incredible, inspiring fireside chat between trailblazing healthcare leader
@SueDHellmann
and our Founder & CEO
@DaphneKoller
. Brace yourself for a week of learning, collaboration & boundless
#innovation
!
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insitro is honored for CEO & founder
@DaphneKoller
to speak to early-career scientists at NIH's Junior Investigators Atlas Builders Meeting, Friday, 11 am ET, NYC & virtually. We're inspired by Daphne's enduring commitment to mentoring junior scientists.
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Thank you to parents, staff & leaders from
@tscalliance
for joining us to share experiences as caregivers & advocates for people living with tuberous sclerosis complex. We're inspired by your courage & commitment to advancing research for
#TSC
patients.
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Our community of cross-discipline collaborators is transforming drug discovery, and we are proud of the dedication, ingenuity and teamwork that insitrocytes display every day. Hear a few members of the team reflect on their 2022 favorite moments.
#HappyHolidays
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Pleased to be part of
@tscalliance
’s 2023 Int'l TSC Research Conference. Today, insitro senior director of neuroscience Jordi Serrats presents the poster "Machine Learning Driven TSC Disease Modeling & Reversion Screening in an iPSC Derived Disease Model."
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Congrats to insitrocytes Kirill Shmilovich, Benson Chen,
@Tkaraletsos
&
@mmsltn
for the publication of their recent paper in The Journal of Chemical Information and Modeling! Read about insitro’s progress in modeling DNA-encoded library (DEL) datasets:
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Join insitro CEO & Founder
@DaphneKoller
tomorrow for a virtual keynote hosted by
@_odsc
. Daphne will discuss insitro’s journey to bring better drugs faster to the patients who can benefit most, through machine learning & data at scale. Learn more:
#AI
#ML
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#AI
brings new opportunities to decode biology to discover & develop medicines for patients in need. Hear insitro CEO & founder
@DaphneKoller
and
@vijaypande
discuss how insitro is leveraging machine learning to transform drug discovery on the latest Bio Eats World podcast.
This week on Bio Eats World,
@vijaypande
dives deep with
@daphnekoller
of
@insitro
into the last few decades of progress in AI, and how she thinks about leveraging AI to drive new insights in biology.
Check it out. 👇
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Join us today as our CEO and founder
@DaphneKoller
presents at the 40th Annual J.P. Morgan Healthcare Conference at 8:30 a.m. PT / 11:30 a.m. We look forward to sharing our vision for the future of drug discovery and development through
#MachineLearning
and data at scale.
0
0
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Our CEO and founder
@DaphneKoller
joined other industry leaders for the
#ForbesHealth
Summit, talking about the role of
#machinelearning
in healthcare and how higher quality data sets can significantly improve our understanding of disease biology. Thanks for having us,
@Forbes
!
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110 insitrocytes strong. Are you team member 111? We are hiring across all departments at insitro and are actively looking for innovative leaders to join our team.
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insitro is excited to host
@SF_WomenInBio
's discussion “AI, AI, and AI – Revolutionizing Healthcare” on Aug. 24, 5:30 pm PT. Moderated by
@drAOPisco
, the panel will explore
#AI
in drug discovery, design & development.
#womeninbio
Learn more & register:
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10
Congrats to insitro Founder & CEO
@DaphneKoller
for being named to
@Forbes
' 50 Over 50, a recognition of women making an impact on the world. Her leadership motivates us every day as we work together to transform drug discovery to benefit people everywhere.
Introducing The 50 Over 50 2022: Women Stepping Into Their Power In Life’s Second Half
#ForbesOver50
@KnowYourValue
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We’re thrilled to welcome Dr. S. Michael Rothenberg as insitro’s CMO. With 2 decades of clinical care & drug development experience, his innovations in data-driven trial design will be critical as we advance our pipeline toward the clinic.
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Excitement is in the air as we prepare to welcome insitrocytes for our 2nd annual insitro in vivo Week – a week of learning, sharing & innovation. This dynamic event brings insitro colleagues from around the world to collaborate & build together, starting Monday!
#invivoweek2023
insitro is on a cross-discipline journey to transform drug discovery. At our 1st "in vivo week," our spirit of learning together showed what makes us special: our culture & colleagues. Celebrate the power of community with us & learn how to join ours at
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Congratulations to our CEO and founder
@DaphneKoller
for being elected to
@statnews
' inaugural STATUS list, which recognizes 46 well-known changemakers in the life sciences industry. Check out the full list below! ⬇️
It’s time to meet the STATUS List!
The most definitive accounting of leaders and influencers in the life sciences
See this year’s honorees:
#STATUSlist
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insitro CEO & founder
@DaphneKoller
is on the road to speak at key events in the UK and Italy. Catch her at London Tech Week tomorrow and at a Pezcoller Symposium on 6/19 to hear the how
#ML
and
#AI
are transforming drug discovery and development.
#LTW2023
#Pezcoller23
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Congrats to our founder & CEO
@DaphneKoller
, 2022 Technical Leadership Abie Award recipient! Elevating women & non-binary technologists is a role we all play. At insitro, Daphne’s visionary & inclusive leadership fosters a culture of respect where excellence thrives.
#GHC22
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Catch insitro CEO & founder
@DaphneKoller
at
@broadinstitute
Machine Learning in Drug Discovery Symposium tomorrow. In her keynote, Daphne will discuss how insitro uses
#ML
& data at scale to identify novel drug targets across multiple therapeutic areas.
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If you're looking for an exceptional team full of smart, collaborative and fun-loving leaders pushing the boundaries of drug discovery, check out our openings!
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At insitro, our cross-disciplinary team pushes the boundaries of science and technology every day to transform
#drugdiscovery
. Join us in using
#MachineLearning
and data at scale to more efficiently identify and develop treatments for patients in need.
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Congrats to our CFO/CBO
@mnrozenman
for making
@businessinsider
's 30 under 40 list of healthcare leaders changing the industry! Mary is an integral part of our team and we're excited to see her hard work recognized. Check out BI's profile on Mary here:
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In the latest
#BehindTheTech
podcast, our founder and CEO
@DaphneKoller
spoke with
@Microsoft
CTO
@Kevin_Scott
about the emergence of digital biology and how our cutting edge work is transforming drug development. Take a listen here:
On the latest
#BehindTheTech
podcast, I talk with one of TIME Magazine's 100 most influential people,
@DaphneKoller
. Learn about digital biology, and how her company,
@insitro
, is making headway in how we treat diseases.
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Join us in welcoming our fellow insitrocyte, Philip Tagari!
#CSO
One of the most rewarding aspects of building insitro is our amazing team. I'm thrilled to welcome Philip Tagari, who joins as our inaugural chief scientific officer after serving as a research leader & drug hunter at Amgen for 24 years. Welcome, Philip!
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(3/3) Congrats to
@SMukherjee89
,
@zrmccaw
,
@JingwenPei
,
@amerkoul
,
@raghav_gt
,
@twsoare
, David Amar,
@somineniHK
,
@christophtklein
, Santhosh Satapati,
@davidjlloydphd
,
@chrisprobert
,
@DaphneKoller
,
@codushlaine
&
@TKaraletsos
. Read our new preprint here:
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Our CFO/CBO
@mmrozenman
will be taking the virtual stage at
@Xconomy
's Xcelerating Life Sciences San Francisco event on Wednesday. Check it out below!
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