Hematology Advisor
@HematologyAdv
Followers
2K
Following
2K
Statuses
4K
Trusted knowledge base of practical information and resources focused on hematology and critical care medicine.
New York, NY
Joined July 2018
The inherited AnWj-negative blood group phenotype is caused by homozygosity for a deletion in the MAL gene, leading to a lack of Mal protein/#AnWjAntigen on red blood cell membranes. Published in @BloodJournal.
0
0
0
RT @myCME: Delays in diagnosing #ParoxysmalNocturnalHemoglobinuria can be critical. Explore diagnosis, management, and expert perspectives…
0
1
0
The addition of D-R for maintenance was associated with a higher MRD-negative conversion rate than observed with SoC R alone in patients with transplant-eligible ND #multipleMyeloma. Reported in @BloodJournal.
0
0
1
RT @myCME: Can ICIs change the frontline treatment of adults with #AdvancedHodgkinLymphoma? New #CME #CE at the @HematologyAdv Institute of…
0
1
0
Among patients with triple-class–exposed, R/R #multipleMyeloma, idecabtagene vicleucel may improve PFS rates over the longer term compared with standard regimens. Published in @BloodJournal.
0
0
0
High antimetabolite dose intensity during maintenance therapy for childhood acute #lymphoblasticLeukemia is associated with elevated odds of hematologic toxicities and hazard of relapse. Published in @BloodJournal. #leusm
0
0
1
A new phase 2 clinical trial is investigating the combination of fedratinib and ropeginterferon alfa-2b as a treatment for #myelofibrosis. Published in the journal @BioMedCentral Cancer.
0
0
1
Procarbazine as part of the eBEACOPP regimen, was associated with mutational burden and novel mutational signatures among patients with #HodgkinLymphoma, which can be mitigated by using dacarbazine instead. #lymsm
0
0
2
#Burnout in US #oncologists has increased over the past 10 years, according to results of 2 surveys. Published in @CancerTherAdvsr.
1
0
0
Patients with #acuteMyeloidLeukemia with NPM1 type D gene mutations are at significant risk of experiencing inferior outcomes. Published in @JCO_ASCO. #AML #leusm
0
0
1
Hematopoietic gene therapy without genotoxic conditioning allows for sustained engraftment and the reversal of bone marrow fibrosis progression in patients with #FanconiAnemia. Published in @TheLancet.
0
0
1
Treatment of #paroxysmalNocturnalHemoglobinuria with ravulizumab was associated with improved adherence and persistence of treatment, as well as better efficacy, compared with other complement inhibitors. Presented at #ASH24. #PNH
0
0
0
Prophylaxis with Mim8 significantly improved physical functioning and reduced treatment burden compared with on-demand therapy in patients with #hemophilia A. From @RareDisease_Adv.
0
0
0
A new post hoc analysis of data from clinical trials has found that emicizumab prophylaxis is likely to improve the pain-related QoL of patients with #hemophilia A. From @RareDisease_Adv.
0
0
0
For patients with #sickleCellAnemia, the addition of hydroxyurea to chronic transfusion therapy was found to be feasible and associated with decreased RBC transfusion volume requirements in a study.
0
1
2
Patients with #multipleMyeloma who were FHR demonstrated a poor prognosis even without harboring traditional high-risk features, including shorter OS. Presented at #ASH24.
0
0
1
Saliva from patients with #hemophilia A appears to aid in blood coagulation despite their deficiency in factor VIII. Published in @BloodJournal and @RareDisease_Adv.
0
0
0
Fertility preservation through oocyte cryopreservation can enable pregnancy in patients with #paroxysmalNocturnalHemoglobinuria who undergo HSCT. Published in @RareDisease_Adv. #PNH
0
0
1