RT @SfNJournals: #eNeuro: Kopf and colleagues directly tested whether MEG background activity reflects hyperexcitability in a patient cohor…

Work conducted at @TueNeuroCampus @uktuebingen @HIHTuebingen @uni_tue and funded by @HertieNeuroSci, @JungStiftung, @dfg_public and @MedTuebingen. In collab. with Pål Larsson and @linjj4. Thanks everyone! (7/7)

We devised an iterative fitting approach to estimate these spectral ‘knees’ in 3 independent iEEG datasets, including publicly shared data by @Kai_J_Miller published in @PLOSCompBiol and @NatureHumBehav, which enabled validating and replicating our approach. Thanks! (4/7)

Turns out: It depends… The PSD exhibits multiple intrinsic timescales (‘knees’) that shape the 1/f decay function. Some of them are state-invariant, while others were state-specific. Moreover, 1/f behaviors differ between different brain regions, such as the MTL and PFC. (3/7)

We and others (e.g., @smpzzz) had previously observed that the spectral slope tracks the hypnogram, but results across studies varied with different fitting ranges (1-20 vs 30-50 Hz). We wondered where should we fit the spectral slope to define distinct sleep stages? (2/7)

RT @MillerLabMIT: A tradeoff between efficiency and robustness in the hippocampal-neocortical memory network during human and rodent sleep…

Work funded by @DAAD_Germany, @JungStiftung and @HertieNeuroSci at @uni_tue, @MedTuebingen, @HIHTuebingen, @TueNeuroCampus in collab. with @JannaLendner, @linjj4 and friends (6/6)

RT @Maikl_Wenzel: Check by a 5yr journey of the lab in mice & humans, just up on bioRxiv! Post-ictal symptoms can be life-threatening, & ba…

For more details and background information, see some of our recent work in @TrendsCognSci and @ScienceAdvances (4/4)