Gunning Group
@GunningLabUofT
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Multidisciplinary team of molecular architects using #medicinalchemistry & #molecularrecognition to design better medicines. 🧵 gunninggroup 🐘 gunninglabuoft
Mississauga, Ontario
Joined December 2019
Thrilled to share our #OpenAccess online resource "An Introduction to Medicinal Chemistry & Molecular Recognition" on @OpenLibraryON! We designed this resource to provide budding medicinal chemists with the knowledge & tools to navigate small molecule drug discovery! #OER
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RT @NSERC_CRSNG: 🗞️ "Characterization of conformational states of the homodimeric enzyme fluoroacetate dehalogenase by 19F–13C two-dimensio…
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Congrats to Motasem in the #Prosserlab and our recent co-supervised alumnus @geordifrere for publishing a new story on tryptophan-based 2D 19F-13C NMR in @rsc_chembio!
Excited to share our new paper in @rsc_chembio on improving resolution in fluorotryptophan protein NMR by expanding into the 13C dimension! We prepared & used a 13C-labelled F-Trp precursor to achieve unprecedented spectral resolution of a F-Trp-bearing protein by 2D 19F-13C NMR!
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We're hiring a #Postdoctoral Fellow in #medicinalchemistry in collaboration with @HDAXtx! Please repost and apply below if you're interested in advancing our novel small-molecule therapeutics! #chemjobs #chempostdoc #postdoc #postdocjobs @ChemPostdocBot
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RT @CommsChem: pharmacophore-optimized photoaffinity fragments-based hit discovery with improved hit rate and better sensitivity, and multi…
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Congratulations to our Sr. Researcher Associate @GeletuMulu for receiving the Rosemary Brown Outstanding Mentorship Award at @CanBlackSci's #BlackExcellenceInSTEMM conference!! Mulu's commitment to scientific mentorship in our community is nothing short of inspiring. #BESTEMM2024
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@NSERC_CRSNG @UTM_CPS @J_A_C_S @TheMediumUTM Geordi has been a pillar of our lab and the larger @UTM community in many capacities throughout his graduate studies. We wish him the absolute best as he heads to @harvardmed to pursue an exciting postdoc in the @GygiLab @HarvardCellBio! #gunningalumni
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RT @MichaelCJewett: Looking for educational kits for #syntheticbiology ? Check out this new frugal #cellfree kit for learning about CRISPR…
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RT @CarolynBertozzi: Cool innovation by @Stanford_ChEMH Institute Scholar @stanleyqilab @MichaelCJewett and coworkers @StanfordEng @Stanfor…
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RT @JinWangLab: I am very proud that Lingfei Wang's thesis work on developing an amplifiable probe for low-concentration analytes is finall…
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RT @KRHornberger: This is a wise and balanced take from Peter, who understands very well that there are no panaceas in drug discovery, only…
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RT @LabWaggoner: p16-dependent regulation of PD-L1 protein stability in senescent cells reveals potential to target PD-L1 to improve immuno…
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To enhance the labelling efficiency and detection of weak-binding #photoaffinity #fragments, an iridium-based photocatalyst was conjugated to the NTD of #STAT5B which promoted #diazirine activation via Dexter-energy transfer. #STAT5 #FBDD
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