Joe
@Gantosj
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Equity market consultant. Technical Analysis Trader with over 25 years of experience. #Biotech Deep dive research. Biotech Trading Analyst @ChimeraResearch
Canada
Joined December 2010
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$SRPT Gene Therapy started!!!
DMD gene therapy went well. It was started at 1:15 PM and ended at 2:27 PM”
Dr. Jerry Mendell bedside a young boy at Nationwide Children’s Hospital
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It's very hard to say last goodbye to the man that affected your life
Led me as a young lad & helped me building my strong personality, gave me the direction &strength to succeed in my life
Thank you dad for the great life you shared with us & cheers for the good 93 years you had
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Looking forward 2020, it will be an interesting year with the election coming & china trade war!
My picks for 2020
1. $SRPT
2. $APTO
3. $PSTI
4. $CRTPF $CRDL.TO
5. $MNDAF $MDNA.TO
6. $BLU
At least 2 or more of these tickers will be a multibagger!
Happy New Year 🎉🎇🎆
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It's pathetic, that AF can't take any criticism, while he is living & breathing criticism all his life!
He blocked me for wondering why he is taking an early victory lap, even before the $SRPT's FDA AdCom vote!
Grow up man.
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Today is the day, I promised my friend Gidi who sent me this bottle of Blue-Label to open it on the day $SRPT close above $60
And it happens to be my Birthday 🎂 as well 😎
Cheers 🍾🥃🥃
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A proud dad day 🤗
My son almost finished his master degree in Medicinal chemistry- Retrosynthesis & his reaction went up from 35% to 95% & ready for publication🤞
His professor convinced him to stay for his PhD & keep the great study that he has done so far for his PhD path 🧐
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Excited & proud dad
My son went today to defend his thesis, and got accepted! 👏
PhD in Organic synthesis
Overarching program is applied BioScience 🤯
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Proud dad 👨 💯
My son 4th year Pharmaceutical Chemistry grads just out.
Next year starting his master 🙌
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$SRPT AdCoM voting positively to approve SRP-9001
Have a great weekend all 🥃
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Thank you to all my 10K followers
What a journey, it was a hard milestone to reach the10K club, but with nonstop DD, charts, discussions & many Under-The-Radar new companies, looking for the next
#multibagger
!
Grateful & excited to continue making new connections here.
Cheers🥃
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I just found out that we lost a very good online friend for IPF, we never met, but bonded a good friendship for over 7 years sharing the passion & support for DMD kids & hope that $SRPT's drug improve their QoL till GT approval.
Greg will be missed 😪
Health update: My IPF has progressed with big impact on my pulmonary hypertension forcing me to use a wheelchair for navigating stores. I can feel pain in my heart now. Seeing cardiologist in March, hoping to last long enough without damage. Using NO2 to dilate vessels for now.
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I got a lot of heat from many critics & haters back in Dec-2023
But I was convinced all the way that $SRPT will get full approval for ambulatory $DMD patients & AA for non-ambulatory
Today we got the same news! Best case scenario
It's a huge win for all
#DMD
families
Now, kids
IMHO $SRPT will get full approval & label expansion for all ambulatory patients & AA for non-ambulatory patients with ENVISION as the confirmatory trial!
What do you think?
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Many are asking me what is your next $SRPT or next $BLUSF
My quick answer, $SRPT is the next $SRPT and will reach >$40B in few years... Also $BLUSF x2 to x3 post Ph2 data mid2020
My next multibagger picks are $APTO $PSTI and the next gem under-the-radar 🇨🇦 company $CRTPF $CRDL
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Nice feeling to end the last 4 months of $SRPT side-way trading on the winning side.
I think this time $SRPT will start curling up starting next week, going to the LGMD conference & then GOLO approval.
Cheers to all of you my friends... we did it 🥃🥃🥃
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$SRPT I want everyone who is saying EMA are right & need a placebo controlled study to approve the "Science", to say same if his son/daughter or grandsons have a rare fatal disease & he's willing to send them to placebo arm & die "FOR THE SCIENCE"
Stop it you all are hippocrates!
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$SRPT And here comes the report we were waiting for!
Long-Term Pulmonary Function
in Duchenne Muscular Dystrophy:
Comparison of Eteplirsen-Treated Patients to Natural History...
#Exondys51
is working & not just for ambulatory kids!!!
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Let's wish Connor an easy biopsy procedure today 04/04, he is the FIRST DMD
#GeneTherapy
patient dosed by Dr. Mendell $SRPT microdystrophin GTx.
Success in this trial will change the life of many young DMD kids for ever!
Pls RT
$SRPT Gene Therapy started!!!
DMD gene therapy went well. It was started at 1:15 PM and ended at 2:27 PM”
Dr. Jerry Mendell bedside a young boy at Nationwide Children’s Hospital
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Most of $SRPT investors knows Billy the warrior, one of the first 12 kids who took part in the first Exon-51 trial & are the reason of
#Exondys51
reaching many other kids.
Today is a special day for Billy, Happy 19th birthday our champ, enjoy your special day🎂🎉
@TerriEllsworth
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What a huge week for
#biotech
& $XBI closing at $97
$PSTI With 340% in 29 days and $APTO ~100% since 03/17 and $SRPT from $78.06 to $121.53 today that's 55%
Time for a good drink, Cheers 🥃
And enjoy your weekend despite the
#SocialDistancing
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The question is not IF, but WHEN $VKTX breaks out the last high & move into triple-digits price over $100
Many big pharma with no weight-loss drug are calling their board for urgent meeting to set the M&A price for $VKTX
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It's the day $SRPT close in triple digits over $100 and the time to crack the Macallan Rare Cask
🥃🥃🥃 cheers Brad, Brian and all the friends around who joined our journey from $8 to $102.29 today
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Congrats to all
#DMD
community, kids & families
You deserve the best for your loved ones & hope Dr. Marks get the FDA's reviewers to common sense & approve $SRPT's SRP-9001
Now time to celebrate 1st battle, next 05/29
Cheers all & happy weekend
Sorry for my 2nd summary of the day
It was a loooong day watching $SRPT's AdCom today
Was very impressed with $SRPT presentation, amazingly good & well balanced.
I was disappointed with some of the advisors who didn't do DD & read the BD
At the end 8:6 for YES for AA
Cheers 🥃
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I just woke up from unlimited naps during the day, fighting a nasty virus to see $SRPT dropping to $122 after the earnings report released.
I don’t get the street reaction!
Elevidys is the biggest near term revenue opportunity in all of biotech
Guidance of $3B in 2025 and the
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It's not a bird & it's not a plane... Maybe it's a rocket 🚀
$ASTS is beating all of my expectations!!!
After breaking out the $6.71 resistance line, we were looking for some technical correction, instead it formed a "FLAG" pattern & broke it faster than anticipated
Now the
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$ASTS Dip & Rip action✅
It was an interesting "Shake the weak hands" action today, with wild 18% swing, dipping to the low $9.32 & bouncing back to close at the High-of-Day $10.98 & above the flag's upper line!
Now the $14.27 line is looking even more appealing!
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Aetna in Pennsylvania reverse the denial for
#DMD
patient & now he is covered
#Exondys51
$SRPT
The drug is medically necessary 👍✅
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1st look @ my 12/31/2019 picks after 6mo & closing prices on 06/30
1. $SRPT $129.04 to $160.34 +24.26%
2. $APTO $4.15 to $6.31 +52.05%
3. $PSTI $3.94 to $8.84 +124.37%
4. $CRTPF $2.72 to $1.75 -35.67%
5. $MNDAF $2.60 to $3.63 +39.62%
6. $BLU $7.60 to $10.29 +35.4%
Looking forward 2020, it will be an interesting year with the election coming & china trade war!
My picks for 2020
1. $SRPT
2. $APTO
3. $PSTI
4. $CRTPF $CRDL.TO
5. $MNDAF $MDNA.TO
6. $BLU
At least 2 or more of these tickers will be a multibagger!
Happy New Year 🎉🎇🎆
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I'm in the stock market for over 30 years & for 15 years
#Biotech
oriented. And what I see today in $MDNAF $MDNA.to is well know as:
Stocks are changing hands from traders who enjoyed 100-200% profits, to a LT investors & funds who are looking for the next x10 or x20 same as
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Funny to see so many pathetic losers who ate so many crows in the past, all tapping each other shoulder & try to look smart & twisting the words from $SRPT CRL
THE FDA CHANGE THE DECISION & APPROVE
#Vyondys33
The dogs barks but the caravan goes on
Will meet you post GTx approval
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That's one of many things that makes
@douglas_ingram
the ultimate CEO.... $SRPT's CEO buy $2M at the open market & put his money where his mouth is
#confidence
#Vision
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The best way to show $XBI
#Biotech
investors that it takes time to show your best data & turns into 🪙
The street can take you down to pennies & trade you as a garbage stock, but as I always say "It's all about the data" then garbage turns to GOLD
$MDNA $APTO $XFOR $EFTR $ARDX
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No target is too high to achieve if you are working hard to get it 🥰
Exciting to see my son presenting his PhD thesis during his FIRST poster presentation at
#QOMSBOC
the symposium for synthetic &
#bioorganic
chemistry in Montreal.
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I used this illustration 4yrs ago for $SRPT & it was so true, many left just before the real uptrend started.
Today it's the same with $APTO & $PSTI where many retail & traders are leaving & the LT investors & institutional keep holding & adding till the hidden diamond is found!
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As promised
@pawcio2009
the Blue Label will be opened when $SRPT reach $60
And today is the day .. Cheers
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Amazing Christmas present from my daughter.
Ace 🐕 like real life... Oil on canvass drawing by my talented artist daughter
What would you rate it from 1 to 10?
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I encourage all to re-listen to $SRPT call
So many points to consider, that might give us a hint, what is behind the optimistic view of Doug & mgnt team?
Looks like the FDA gave them positive view based on TTR p=0.0025 (full approval)
Slides from the call
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Wow, I'm following $SRPT for almost 14 years
Went through the excitements & disappointments as well, riding many roller-coasters with so many important events.
Today, I feel that we are close to the end of the story, where every
#DMD
kid can get treatment, despite what other
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$SRPT just look at the tissue in the 4th patient biopsy, looks like a normal muscle fiber!!! Nothing to add to this picture, worth 1000 words
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Only if you know who is Prof. Brian Druker & how high ranked in the hematology research he is, then you will appreciate this quote about $APTO :
"If the preclinical safety profile of CG-806 continues in humans, CG-806 has the potential to be among the very best KI I’ve seen"
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Ok, couldn't resist it, it's not $75 but RED to GREEN and then close @ $74.35 in $SRPT worth starting the weekend with this nice 15 years puppy.
Cheers to all my friends around the world 🥃
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Another $VKTX trade!
#BULLISH
Selling 1000 Apr $50 put
Buying 1000 Apr 70/90 spread
Total debit $3.70
$VKTX options buyers have guts & looking for a huge run into Jun & Jul with large bets on Jun $120 calls & Jul $140 calls
Personally, I prefer close or ITM calls
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$SRPT – Preparing For Blast Of Catalysts
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Great news, Cash Huber finally gets Highmark approval for his
#DMD
genetherapy .
Thanks to all those who took part & signed the petition & helped overturn the decision.
$SRPT
Please sign this petition & help Cash Huber to get his
#GeneTherapy
treatment for
#DMD
before the deadline of turning 6 years old. $SRPT
Highmark Delaware: Approve This Life-Changing, FDA Approved Treatment For My Son.
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$ASTS breakout confirmation candlestick... Next is the $8.02 weekly resistance line.
Also the 50MA is curling upward & will cross the 200MA upward in the next 2-3 weeks
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$ASTS is flagging & getting closer to the breakout!
If we take ONLY the technical standpoint (ignoring the fundamentals for a bit) then the flag pattern gives us price target of $14.95 a move of AT LEAST $5.35 (length or the flag's pole)
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$SRPT Hiram is the 1st child in the world to receive the treatment after it was approved by the FDA.
The difference in his life post-
#ELEVIDYS
treatment is remarkable. The change started just a week or two after the treatment and has continued ever since.
“His endurance is
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Ace 🐕 finally getting his grilled rare steak, so excited that he couldn't say I Love You as he always do, it's OK, he was waiting for so long to get $SRPT close over $95 🥃
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To get the next targets for $ASTS, I have to use the 3 years chart!
If we cleared the $11.35 line... Next target is the $14.27 weekly line followed by $15.48
$ASTS after the "flag's upper line" breakout, then the retest of the line & 3 days closing above it, today we are getting the confirmation of the breakout, running up & printing a New-52W high $10.74
More to come IMO with the positive momentum!
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$APTO
#ASH20
summery
3 drugs are progressing well & in "Therapeutic dose"
🟢253 MYC inhibition will be targeted by big pharma for combination drug
🟢CLL 750mg is active drug with nodal reduction, next PR
🟢AML reduction in %Blasts from 93% to 10% clinical anti-leukemic activity
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$VKTX options buyers have guts & looking for a huge run into Jun & Jul with large bets on Jun $120 calls & Jul $140 calls
Personally, I prefer close or ITM calls
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Proud dad, my daughter graduated from art college with "Illustration" diploma
She was in art school since grade 9 & finished first college program in 2019 "Creative advertising & art director."
Now she will start the hunt for the right job & career 👏
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Put your money where your mouth is!!!
$SRPT director Chambers Michael Andrew is buying at the market 37038 shares at avg ~$134 & total of ~$4.96mm
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Keep watching all the crows eaters getting out from their deep holes to ask why $SRPT got GOLO approved....
It's time to tell them all, fu#*off & eat another crow
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$SRPT A 5 years follow-up tells us the Gene Therapy SRP-9001 works
Since receiving gene therapy, Will Ungerer can do everyday things, including climb stairs easily and get dressed on his own.
He can ride a bike and swims up to 500 meters at swim team!
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$SRPT & Lysogene Gene-Therapy clinical trial in
#Sanfilippo
#MPS3A
The mother share here daughter Lulu progress post GT treatment
5 weeks after GT: Faster. Flat footed. Knee & foot centered, More upright/not crounched
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Ace 🐕 is getting his striploin steak as promised after $APTO breaking out & closing above both the 200MA & the $6.40 weekly resistance line. 🥃
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I have been fascinated by the power of IL-2 in cancer treatment for years.
$BMY $SNY & $RHHBY failures added a dark-cloud over IL-2 space, but latest data from $MDNAF $MDNA.TO brings back hope for the Best-in-Class IL-2
My deep dive into the history & future of IL-2
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I just got a call from my son asking, dad you was excited about $APTO reaching $9, now it's $7.9, is it a good point to add to my position, I just got my paycheck?
Smart kid, he's with $APTO from $1.80 & $4.20 & now $7.90 with avg ~$4.6 & will hold till M&A to buy his new car📈
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Usually I'm trying to stay away from Twitter during the weekend & not to reply or post anything!
But, I was tagged to a long $SRPT tweet by a guy that I respect & wish
@Biohazard3737
can think again and remove his post that is not accurate nor have any support for the numbers he
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$XBI One of the longest downtrends during the past 20 years in
#biotech
July 2015 till Feb 2016 were a tough 7 months long.
But this time 11mo from Feb 2021 till Jan 2022 & still no reversal sign yet.
But it's deep in oversold territory same as Feb-2016 just before the reversal!
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Just think about the parade after
#Golo
CRL and all the haters pushing
@douglas_ingram
hard to release the full CRL while I never saw any other co. did it before.
But $SRPT's CEO was wiser than all, kept things quite & used the proper tools to fight with resubmission process!
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We are getting closer to some important scientific conferences that can change the companies' valuation drastically!
1. $VKTX VKTX2735 data at the Obesity Week San-Antonio TX Nov 3-6
2. $MDNAF $MDNA.to to present it's
#IL2
data from mono & combo study Nov 6-10
3. $CRDL To
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$SRPT & Lysogene GT clinical trial in
#Sanfilippo
#MPS3A
Lulu's mom share her progress post
#GeneTherapy
treatment
11 weeks: Lulu’s school re-evaluation, in the past year Lulu has shown progress in every single category. Most importantly her cognitive age increased by 6 months
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Proud dad 👨👩👧, feeling high sky when my son gets an email from his lab professor telling him, good news U got A+ in Advance topics in medicinal chimestry - Retrosynthesis.
And before you apply anywhere else for your master, let's chat, I got funding & love to have you with me 💯🙏
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Just a quick reminder to all retail $SRPT shareholders
I know that we went through a lot of manipulation & everyone is happy to bank profits at $165 - $170
But, look at the full picture, $SRPT had a homerun scenario with best case scenario as we all dreamed of full amb.
Huge win to $SRPT
As I was saying all the way ling, full approval for amb patients & AA for non-amb.
Approved to all ambulatory patients over 4 years
& AA for non0ambulatory
Full label
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Take a breath & think about what changed in $SRPT from 06/19 till today?
The clinical hold is due a 3rd party manufacture issue that will be solved very quick!
The plan to start the GT Pivotal trial by year end is still in place!
Remember the UK clinical hold buy opp. same here!
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$SRPT is building Gene-Therapy Powerhouse!
1. Micro-Dystrophin-NCH
2. GALGT2 - DMD
3. Micro-Dystrophin-Genethon
4. LGMD2E
5. LGMD2D
6. LGMD2C
7. LGMD2B
8. LGMD2L
9. Pompe -Lacerta
10. CMT -NCH
11. MPS IIIA -Lysogene
12. CNS 1 -Lacerta
13. CNS 2 -Lacerta
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$APTO Mcap today is only $553M @ $7.25/share!
If CG-806 keep showing safety at 450mg &next 600mg and start showing PR, then $ARQL M&A $2.7B is the base which gives $APTO ~$35
But if AML study works too, then $4B or >$50/shr is the lowest target IMO & 253 is the cherry
#TimeStamp
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New drawing by my daughter, just expand and take a look at the small details ✨️
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$SRPT got what every
#DMD
parent was praying for!
Full approval 4 years & up ambulatory patients
AA for non-ambulatory is a dream come through
I don't know if I can sleep tonight!
Huge win to $SRPT
As I was saying all the way ling, full approval for amb patients & AA for non-amb.
Approved to all ambulatory patients over 4 years
& AA for non0ambulatory
Full label
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Amazing change just after 68 weeks on $SRPT's
#Exondys51
.. Austin showing benefit in Non-Ambulatory population
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$SRPT
my son Max, a participant in SRP-9001 clinical trial
Max received experimental gene therapy at 6 years of age and he is now 8 years old
2 days before his 6th birthday & this has been the best birthday gift he has ever received H/T
@SteveHa64191820
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$ASTS bouncing from the Fibo-50% correction line, with the Stochastics rolling upward to leave the Over-Sold territory, next $13.15
De-risked after the successful launch & BW 3 is comfortably roaming around the globe, thermally stable & communicating with $ASTS ground stations!
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A story to all those who are still don't get it why Dr/ Marks is supporting approval for $SRPT's Elevidys.
Carter’s CK levels were extremely high — 18,201, instead of the normal level of 60-305 for children in his age range!
On Nov. 1, Carter finally headed to Texas Children’s
Texas Children's Hospital patient is first in Texas Medical Center to receive gene therapy treatment for Duchenne muscular dystrophy
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Wow, so good to Austin is doing great at age of 20, look at the new beard face with the same great smile... thanks to $SRPT's Exondys51 that had so many haters.
BUT they all would grab it in 2 hands if it was their own kids!!!
Cheers Austin & best wished to Max
Today is the 5 yr anniversary-Austin’s 1st dose of
#exondys51
. Today he is a thriving 20 tr old, with no breathing assistance, the ability to feed himself, attend college- he is living a normal life. A huge thank you to those who helped make that possible ( $SRPT)
#thenandnow
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Haters gonna hate, & unfortunately there are many around $SRPT, some pretend to be experts (still thinks like a dinosaur), but they won't change my conviction!
Started investing in $SRPT many years ago ~$12 & added at many events along the road 📈
I liked it for the trade & got
$SRPT one of THE most hated biotech stocks and one bashed most on social media and by pundits.
However, it is the biggest winner from that pullback to low teens on negative adcom vote to eventually getting AA and hitting all time highs close to $180
@Gantosj
and myself got some
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Cancer drug development is a very hard process, some succeed &some failed!
You can be +ve or -ve, short or long, or sit on the sideline
$APTO's 806 is working on both CLL & AML FLT3
Dr. Drucker is a pioneer in cancer drug development
Jump to 46:45 &listen
0
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$ARDX Chairman of the board MOTT DAVID M, buys 567K shares in open market at average $1.7648
Why would the chairman buy in the open market?
Looks like the chances of a public offering are lower, maybe waiting another 30 days for FDA response!
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You won't believe it, if you don't watch this video of Lulu riding bike post her
#MPS3A
Gene-Therapy by Lysogene, $SRPT's partner, 9wks still hardly moving & need help & to racing after 15 weeks 👏
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$ASTS, the $14.27 weekly line breakout brought in a stealth move to find a strong resistance at the channel's upper line... Got rejected twice & today is the sell-off
But, overall $ASTS is in a healthy & strong uptrend channel & the bulls will by the dips & push the price higher
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$SRPT amazing to see the cardiac & smooth muscles results. PPMO in NHP results... the 80mg/kg can bring almost 90% exon-51 skipping
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No.need waiting till the closing bell, $SRPT will close above $65 today 😋 and as promised y buddy Charles we will crack the bourbon bottle.. for me 1st time American Bourbon 🥃
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My take from today $SRPT AdCom is the some advisors are coming in with predefined decision without even listening to the discussion
One member Christopher “Buddy” Cassidy, the patient representative was a 10 levels of understanding above the whole panel members.
Life experience
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