Johannes Walter
@FrogWalterLab
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Excited to share (with my 8 followers) graduate student Ernst Schmid’s “SPOC” classifier, which can pick a good AlphaFold-Multimer prediction out of a crowd, and , a database of PPIs in the genome maintenance space.
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Please RT: The Walter lab at Harvard seeks computational biologists to extend our work using AlphaFold to find new protein-protein interactions. Contact johannes_walter
@hms
.harvard.edu
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A warm thank you to Lumír Krejčí for hosting my Mendel lecture in Brno, Czech Republic, home of a vibrant scientific community, the marvelous Tugendhat Villa, and of course, Gregor Mendel. To stream Mendel lectures:
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Comprehensive model of how the replisome bypasses G4 quadruplexes. Intricate mechanism involving one accessory helicase that helps CMG bypass the G4, and a second helicase that subsequently unfolds the G4 for nascent strand extension. Beautiful work!
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