Jonathan Afilalo
@FrailtyMD
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Clinician scientist. Voracious learner. Director of McGill Geriatric Cardiology Program. Creator of https://t.co/PVflDwZCSD & https://t.co/4IJWOncQte.
Joined January 2018
RT @MWeintraubMD: SGLT2 inhibitors paradoxically have greater cardiovascular protection in older adults compared to younger adults with T2D…
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Exercise may not make you immortal, but it can protect your telomeres—a marker of cellular aging. This meta-analysis shows small-to-moderate effects on telomere length (effect size 0.3-0.4). Largest effects in older adults and HIT 🏃♂️🏃♀️🏃
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The ol’ hangin’ arm technique overestimates SBP by 7 mmHg (!)
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Vitamins B3 and B6 for regeneration of aging muscle - an exciting prospect for nutraceutical treatment of sarcopenia 💪
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RT @SamuelBHume: 5. A treatment to prevent weight and muscle loss (cachexia) in cancer Cachexia is driven by the stress-responsive cytoki…
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RT @HanCardiomd: #LVEF and #ICD in Non-ischemic #HFrEF : Insights from #DANISH In patients ≤70 years, LVEF didn't influence ICD benefit, b…
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RT @drahmedmohsen85: The target BP values in hypertensive patients have been changed in the new ESC Guidelines
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✨ Wish list ✨ a not too burdensome questionnaire to evaluate all subdomains + overall social frailty (current tools somewhat fragmented)
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GLP1 usage skyrocketing in obese HFpEF patients but age bias is stronger with this 💊 than any other GDMT, why? 🤔 @JACCJournals
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RT @ESC_Journals: SGLT2i can reduce the incidence of new-onset diabetes among individuals with cardiovascular or kidney disease. Read more…
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If your cardiac surgery patient has low muscle mass on their preop CT scan they are… 2.5X more likely to die 2X more likely to be discharged not home +2 more days in hospital
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RT @DrDamluji: Invasive Versus Conservative Strategy in Older Adults ≥75 Years of Age With Non–ST‐segment–Elevation Acute Coronary Syndrome…
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Neural networks have been around since the 1950s so why did it take 50+ years for them to become primetime? 3 simple reasons (with slides from my presentation @CJCJournals symposium #CCC 2024): 🧮 Better math [back propagation 1980s] 🛜 Better training data [the internet 1990s] 🖥️ Better compute [@nvidiaGPU 2000s] These breakthroughs enabled deep multi-layer networks that could learn new features from many different types of input data and recognize complex non-linear patterns to make highly accurate predictions
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RT @JuliaRodighiero: Incredibly honoured to present our abstract at #CCC2024 and to receive the Best Abstract Award from the Canadian Socie…
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TLDR 🙅🏻♂️
A recent meta-analysis of randomized trials assessed the performance of resveratrol in improving various metrics of metabolic health.
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RT @HeartInstitute: How are physicians using #AI? We’ve met with Drs @FrailtyMD and @RobertAvramMD to understand how #AI supports their wor…
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RT @CJCJournals: 📢 #HotOffThePress! The newest Focus Issue of #CJC on "Rapidly Evolving Clinical Applications of Artificial Intelligence" i…
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RT @KostasProko: Alfonso Cruz-Jentoft on the recent definitions of sarcopenia and sarcopenic obesity, and some guidance on the (personal) a…
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RT @DrDamluji: 🥸1️⃣6️⃣ Overall, BIS-guided decongestion was associated with lower hospitalizations and deaths over 12 months.🥸 https://t.co…
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