ᒍOᕼᗩᑎ ᗪᑌᑕᕼEᑎE
@DucheneJohan
Followers
1K
Following
1K
Statuses
535
Dad, husband and scientist | Immunology, Chemokines and Atypical ChemoKine Receptors | Research and Metaresearch @ipekresearch @LMU_Muenchen @lmu_osc
Munich, Germany
Joined September 2018
RT @RetractionWatch: "Alzheimer’s scientist resigns after university finds ‘data integrity concerns’ in papers." ht…
0
18
0
RT @slavov_n: This rate of validation suggests that antibodies should be considered non-specific until proven otherwise: 357 validated out…
0
116
0
RT @OxygenIvan: @slavov_n I have been arguing that we need to go back to basics. The pressure for hypercomplex papers kills the very fabric…
0
6
0
Journal Editor: "What is the mechanism?" Scientist: "Better than an answer—I have a tremendous amount of data!"
0
0
7
RT @Vasculearn: Exciting news clinician friends and colleagues. Our brand new podcast series, "Clot, Clot, Who's There?" in partnership wit…
0
7
0
@ATH_Plus @ELS_Cardiology @society_eas Once again, passenger mutations inherited from the 129 strain surrounding the gene of interest lead to phenotypic issues
0
0
0
RT @ATH_Plus: SMC-specific deletion of Ccl2 in mice does not impact atherosclerotic plaque size or composition, suggesting SMC-derived CCL2…
0
2
0
RT @timeshighered: Germany’s decision to sign a national agreement with open access publisher MDPI has been criticised as “highly problemat…
0
5
0
RT @DanielJDrucker: After only a few days of 2025 it is clear we continue to value the fantastic and fabulous over the rigorous and reprodu…
0
12
0
Hayes explains that in ACKR2 knockout mice, passenger mutations inherited from the 129 strain affect CCR2 expression in natural killer cells, resulting in confounding effects.
1
1
7
NIH launches initiative to double check biomedical studies | Science | AAAS
0
0
5
@LindsayWu_UNSW While it is often the case that antibodies from Santa Cruz are bad, other companies also sell non-specific antibodies. We had a bad experience , check here:
4
0
0
Also a reminder that isotype controls are not a reliable method for testing antibody specificity, as only knock-out organisms can definitively demonstrate antibody specificity.
Why Bax detection in >1400 publications might be flawed? The culprit: a poorly validated antibody that went unchecked for years … until recently !!!
0
1
7
@structureltp It is indeed an issue that we all have encountered at some point. You may find these articles interesting to read:
0
0
1
RT @slavov_n: The majority of respondents do not think that RNA-seq has transformed our understanding of tissue structure. Yet, many art…
0
4
0
RT @slavov_n: Has scRNA-seq transformed our understanding of how complex tissues are structured ?
0
4
0
@SeanDavidsonHCI I also like the supplemental file with the list of all studies that used the Ab and the information about the methods employed.
0
0
2
@CoskunPLID It is indeed an issue that we all have encountered at some point. You may find these articles interesting to read:
0
1
12