Carol Sheppard
@Dr_Shepp
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Molecular virologist with a passion for polymerases. Advocator for equality and environmental sustainability and anything that can be done from a hammock.
London
Joined June 2020
RT @SanchoShimizu: *****JOB ALERT***** Research Assisstant with expertise in computational biology wanted to work on cohorts of patients w…
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@fozzz21 @IMIBirmingham Thanks for the invite! Lots of great questions and fruitful discussion. Always a pleasure to see familiar faces.
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It's often these fleeting interactions that can really shape the person you want to be.
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@TheEthanIverson @influenzal The idea that ANP32 could be a more "universal" host factor is something we have explored, especially as polymerase dimerisation is not unique to influenza. Prelim results weren't encouraging but we have better tools now should someone have a mini-replicon system/virus to test.
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And how we exploited this strict host dependency to take the first cautious steps towards the generation of gene-edited chickens that a resistant to flu
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Understanding the mechanisms of FluPol regulation by host proteins has been keen to responsibly designing novel therapeutic approaches. Excited to finally share our back-to-back Nat Comms papers!
***PAPER ALERT*** So excited to have this out @Dr_Shepp joint production We asked what happens if you take away a key host factor from influenza? What cool virology can you uncover? Polymerase Dimers! ANP32 in mice and chickens?! Read on for more...
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RT @influenzal: 🚨🚨JOB ALERT🚨🚨 Are you a recent Master’s graduate? Interested in evolution of viruses? Want to do 12 months of research? H…
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RT @royalsociety: A new Royal Society scheme to kickstart the independent research careers of researchers from groups underrepresented in U…
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RT @ant__eater: #EFIC_org I will be talking about my research using stem cell models to investigate a Painful Hereditary Neuropathy at 2pm,…
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RT @doctorveera: A mind-blowing paper has come out today in @Nature In 2016, JC Venter Institute scientists trimmed a bacterial genome t…
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RT @NatureBiotech: Happy National DNA Day!🧬 In this @nature Comment, newly discovered documents reveal Rosalind Franklin was no victim in h…
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How flu alters it's polymerase in order to adapt to differences in host species proteins.
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It's only taken 5 years of working at St Mary's hospital but finally visited the Alexander Fleming museum - birth place of Penicillin.
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