Michael Eisenberg
@DrMEisenberg
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Urologist @Stanford specializing in Male #Infertility , #Sexual Function, #MensHealth . HealthTech Advisor. Entrepreneur.
Palo Alto, CA
Joined September 2011
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Honored to join and discuss all aspects of Men’s Health
New Huberman Lab podcast:
IMPROVING MALE SEXUAL HEALTH, FUNCTION & FERTILITY w/Dr Michael Eisenberg MD of
@StanfordMed
•Prostate & Sperm Health
•Trends in Penile Length
•Testosterone & TRT; Facts & Myths
•Erectile Function
•Science & Protocols
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Do cell phones impact semen quality? New
@FertStert
study shows cell phone use 20x per day associated with 30% increased risk of low sperm count. No association with where phone is kept. But impact less over time (newer phones) so maybe okay now.
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New data continues to come out about this important question. Recent
@FertStert
reports cell phone use 20x per day associated with 30% increased risk of low sperm count!
There is a relationship between cell phone carrying in front pant pockets & sperm DNA fragmentation that is independent of heat effects. Dr Eisenberg, MD, Urologist & Male Sexual Health/Endocrine expert
@StanfordMed
explains on the Huberman Lab podcast:
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Couples ask about effects of waiting to have kids. New data shows no consistent association with age of parents and semen quality of sons.
#MensHealth
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Projected fertility services up to $90B per year in the next 3 years. 14% growth per year. Bad news for reproductive health of species. Good news if you are in fertility business.
@AHParis_org
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New research from
@jama_current
shows that folic acid and zinc supplementation for men may not help improve male
#fertility
(Live birth 34% vs 35% with treatment vs placebo)
@eschisterman1
@sunnimum
@NICHD_NIH
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While testosterone therapy can benefit men, there has been concern about negative effects on prostate (i.e. cancer or growth leading to urinary symptoms). TRAVERSE Trial showed no increased risk with T therapy.
#MensHealth
Prostate safety is a concern of men considering testosterone treatment. In the TRAVERSE Trial, a large testosterone RCT in men with hypogonadism, rates of prostate cancer and other prostate events were low and did not differ vs placebo.
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Our new study in
@WJMensHealth
of 55K men shows that men’s average erect penile length has increased 24% (from ~ 4.8 in to 6 in) over the past ~30 years.
#MensHealth
@stanfordmed
@stanfordurology
@FedericoBellad1
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Does job matter for sperm count? This study says lifting heavy objects and more physical activity at work is associated with higher sperm and testosterone levels.💪
@Eshre
Human Reproduction
#MensHealth
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More than 8k steps per day led to the biggest reduction in the risk of low testosterone
@f_delgiudice
@StanfordUrology
@StanfordMed
#MensHealth
If you're trying to boost your T
Here's an easy tip
Walk more
That's right
"There is an association between testosterone levels and step count [...] If you walk more, you will see higher levels of testosterone." -
@DrMEisenberg
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Sperm motility among Danish sperm donors declined 30% from 2019 to 2022, ? COVID - disease itself or adverse lifestyle changes that increased (sedentary, isolation, etc)
#ESHRE2023
@AllanPacey
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A true honor to join the team.
1/
@FertStert
would like to introduce you to the newest members of our editorial editors team
Today - please meet Dr. Michael Eiseinberg (
@DrMEisenberg
)
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A new study in the journal Andrology
@AndrologyASA
reports ~40% of men who freeze sperm ultimately use it (prior studies suggested <10%). Usage rates increase at older ages at time of cryopreservation. Fear of paternal age effects?
#MensHealth
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Excellent talk by
@R_Rahbari
at
#ESHRE2023
Fathers contribute 78% of all de novo mutations. Mutations increase with age. Exciting new data on impact of some cancer treatments on sperm DNA
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Amazing achievement given complexity of the Y chromosome. Big moment for
#MensHealth
May lead to more diagnostic and therapeutic options for male fertility.
Nature research paper: The complete sequence of a human Y chromosome
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Our new study in
@WJMensHealth
of 55K men shows that men’s erect penile length has increased 24% (from ~ 12.3 cm to 15.2 cm) over the past ~30 years.
#MensHealth
@stanfordmed
@stanfordurology
@FedericoBellad1
Thanks for highlighting
@kweintraub
Amid declining male sperm counts and testosterone levels, the researchers expected evidence would show that penises are shrinking as these levels fall and men get more obese.
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First in person meeting in over a year. Great to be back out. Listening to AUA lecture by Marc Goldstein on the importance of the male fertility evaluation
@ReprodMed
#ASRM2021
@TripActions
#LetsGo
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So far, no pregnant women with the
#coronavirus
have passed the virus to the child. However, the case numbers are small and the
@CDCgov
still considers the risk unknown.
Due to the unknowns,
@ReprodMed
and
@ESHRE
recommend against pursuing new fertility treatments for now.
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Don’t forget the father.
#MensHealth
Paternal health matters.
New from
@DrMEisenberg
@MaartenWensink
: Preconception paternal
#metformin
use is associated with major birth defects, particularly genital birth defects in boys. Authors suggest further research to clarify the causation .
#diabetes
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Important study of 25K men from around the world examined factors associated with men's testosterone levels
Lower T: age, BMI, marriage, high BP, cardiovascular disease, less exercise, diabetes, worse general health
#MensHealth
An analysis of more than 25k men found that high BMI, diabetes, and cancer were associated with lower testosterone in men aged 70 years and older:
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Honored to participate in important review of
#MaleInfertility
including epidemiology, physiology, evaluation, treatment, patient impact and the future of the field
Our NEW Primer on Male infertility is live today! By
@DrMEisenberg
, Esteves,
@DlambJ
,
@jimhotalingmd
, Giwercman, Hwang & Cheng.
Check it out here:
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From Dr. Michael Eisenberg
@DrMEisenberg
during the Panel Discussion: Is Advanced Paternal Age a Health Risk for the Offspring? happening now in the Plenary
#AUA21
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Excited for the session today starring
@RodTMitchell
on fertility preservation in males with hereditary cancer
#ESHRE2023
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Not everyone realizes that cystic fibrosis can affect
#fertility
Male: absence of vas deferens leads to obstructive azoospermia
Female: thicker mucus
Fortunately, treatment is effective.
This article discusses this and other aspects of CF.
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When dads stay home after birth, mom's health (overall and mental) improves. Research from
@StanfordMed
@Stanford
and Sweden
#MensHealth
#DontForgettheDad
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Dr Nils Lambalk (EIC Human Reproduction) showing projected costs of fertility services in the next few years.
@AHParis_org
@ESHRE
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Great summary of guidelines for management of priapism (ie. prolonged erection of the penis) based on
@AmerUrological
@SMSNA_ORG
guidelines.
#MensHealth
@rebrannigan
@UroFantusy
JAMA Clinical Guidelines Synopsis discusses the diagnosis and management of priapism.
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Father plays an important role in child's health. Thanks for profiling our work.
@nytimes
@StanfordUrology
@StanfordMed
#MensHealth
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Good diet, exercise, and maintaining a good body weight will benefit overall, testicular, sexual, and reproductive health. All great motivators.
#MensHealth
Testosterone levels are declining (by generation). The reasons are clear: more obesity, less walking & other physical activity, heat (& maybe RFs) from cell phones & fatter legs. The remedies thus are clear too. Male hormone, sexual health expert Dr Eisenberg of
@StanfordMed
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Analysis of over 40M births in US.
#MensHealth
@StanfordUrology
@StanfordMed
@Stanford
@StanfordHealth
What is the impact of advanced paternal age on maternal and perinatal outcomes? New
#BMJResearch
@drmeisenberg
with editorial
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Honored to participate in
@Yale_Urology
course. Great lectures. Engaged participants. Lots of laughs and learning.
#Bulldogdebates2023
Day
#2
kicked off strong by andrology.
@DrRotker
@DrMEisenberg
& Dr Honig duke out Shockwave for ED, pre-RARP penile rehab, & Tx of Sever Petronies. Awesome keynote by
@DrMEisenberg
on sperm health & overall health.
@Yale_Urology
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Excited to participate
Detailing the reproductive + sexual medicine portion of our upcoming CME event in
#NYC
. Still time to register➡️
🔷🔑note is
@DrMEisenberg
"The 6th Vital Sign: What Our Sperm Are Trying to Tell Us"
🔹Then 3 "Bulldog Debates" w
@shonig
, MD
🔹&
@DrRotker
, MD
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Honored to participate.
Attention all urologists-- join us in NYC 9/30-10/1 for our CME accredited event. Cutting edge, controversial urologic issues will be covered in a debate format.
More Info➡️
Registration➡️
#MedTwitter
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Thank you so much for this great honor.
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Very excited for Evan to join the team!
Congrats to
@emory_urology
chief Resident Dr. Evan Mulloy who will be going to
@StanfordUrology
next year for his Male Reproductive Medicine fellowship with
@DrMEisenberg
👏👏👏
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I'm commonly asked about cannabis use and male fertility. Using monkeys, the investigators showed chronic THC exposure leads to smaller testes and lower testosterone levels. Some improvement after exposure stopped.
#MensHealth
Cessation of chronic delta-9-tetrahydrocannabinol partially reverses impacts on male fertility and the sperm epigenome in rhesus macaques
Full text 👇
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COVID vaccination prior to conception (for mom or dad) not associated with miscarriage.
#MensHealth
@jennifer_yland
’s paper on COVID-19 vaccination & miscarriage is out! Preconceptional COVID-19 vaccination in either partner was not associated with increased rates of
#miscarriage
.
@AKWesselink
@DrMEisenberg
@AnnetteKRegan
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Advanced paternal age is associated with negative effects on both mothers and offspring. While the absolute risks remain low, these findings emphasise the importance of including men in preconception care
#BMJResearch
@DrMEisenberg
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#ICYMI
from
@DrMEisenberg
@MaartenWensink
: babies born to men who took metformin during the period of sperm development were at increased risk for birth defects:
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Sperm can survive in zero gravity.
#PowerfulStuff
#MensHealth
Microgravity sperm experiment suggests babies can be born in space, scientists say
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If you do one thing today, read/watch this! Thx
@engadget
@Mr_Trout
#MensHealth
Personal journey in male fertility
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Honored to join the program. Will be fun to be back to
@Yale_Urology
where I was first introduced to urology years and years ago.
We're excited to have
@UCSFUrology
's Thomas Chi, MD,
@StanfordUrology
's Michael Eisenberg, MD, and
@bcm_urology
's Seth P. Lerner, MD, join our own leaders as keynotes for this destination CME event⬇️
Registered?
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The debate about falling birthrates is whether it's due to drops in desired family size or biologic ability (ie. falling sperm counts). But that's why reproductive research is so important - it's existential!
#MensHealth
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Great presentation on factors associated with
#MaleInfertility
by
@SarahWolde
and
@msirota84
Some very novel factors identified!
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Important work on drop in sperm counts and thoughtful examination of why (eg environment, lifestyle)
@bryanrwalsh
#MensHealth
@TrakHQ
The male infertility crisis: Who's killing America's sperm? Read our latest cover story
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Maintaining cardiovascular fitness (eg cycling) is usually good for erectile function, but some men can develop issues due to bike saddle.
#MensHealth
@StanfordUrology
@thevseat
Yes, bicycle seats can cause sexual health issues in men. No, most erectile issues are not related to hormones, but rather blood flow and neural issues. There are also straightforward solutions. Learn more from
@DrMEisenberg
Urologist
@StanfordMed
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Need data collected from mobile devices to fit into workflow for clinicians.
@Idasim
#bigdatamed
@StanfordMed
http://t.co/cqjSMFS8py
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Important piece on falling sperm counts. Would be important step to start tracking sperm counts
@CDCgov
@NCHStats
Thx
@RA_Becks
#MensHealth
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It’s mutual.
MFW I found out I matched to
@StanfordUrology
for my Andrology Fellowship with
@DrMEisenberg
!!Couldn’t be more honored and excited 🎉 So humbled by all of the support from
@uwurology
@tjwalshsea
@SorensenMathew
@WessellsHunter
#Goodtimesahead
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Great coverage by
@NBCNews
on falling sperm counts in Western countries. Urgent need to assess and
@TrakHQ
semen quality.
#MensHealth
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New tissue filler tested for penile enhancement injections in Korea. Need long term data before trying at home.
#MensHealth
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Some question about whether
#5ari
(like
#finasteride
) may lower risk of
#BladderCancer
. In this study of >1M men, we did not find any change in risk.
#MensHealth
US🇺🇸 insurance-claim data shed light on debated role of
#5ARi
w/o
#alphablocker
and their potential
#chemoprotective
efficacy against incident
#bladdercancer
@AmerUrological
@Uroweb
@EAU_YAUrotheli
@DrMEisenberg
@FedericoBellad1
👉
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Average dad's age at birth of child
1972: 27.4
2015: 30.9
3.5 year increase!
Thx for highlighting our work.
@susanscutti
@stanfordmed
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One step closer to using prepubertal tissue. Thanks
@RA_Becks
Sperm from a frozen chunk of testicle helped create this baby monkey
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Thx
@MensHealthMag
for profiling our work on male
#infertility
in the April issue
@StanfordMed
#MensHealth
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Thx for highlighting our work.
Regular marijuana use linked to more sex, study finds:
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The latest Silicon Valley Urology Times! Thanks to
@urotoday
@AmerUrological
#eauguidelines
#prostatecancer
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Preview of the future of medicine courtesy of
@TracyALieu
from Kaiser
#BigDataMed
http://t.co/1AhFqa7ofA
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US men die 6 years earlier than women! Widening gap over the last decade. Unintentional injuries, COVID, and overdoses all contributed. Hopefully the next decade brings improved life expectancy for all.
US men die younger than US women by nearly 6 yrs. New research uncovers causes for the widening gap since 2010. The findings expose critical disparities relevant to public policy.
@BYan415
@DrHowardKoh
@HarvardChanSPH
@UCSFMedicine
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In honor of
#420day
One of our studies from 2017
"Clinical Implications: Marijuana use is independently associated with increased sexual frequency and does not appear to impair sexual function."
@jsexmed
@StanfordUrology
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Does the amount of
#sleep
affect serum
#testosterone
levels in men and women? A new study using data from
@CDCgov
NHANES finds little consistent relationship. Nevertheless, sleep is important!
#MensHealth
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Reproductive health = overall health
Sperm science benefits
#MensHealth
How infertility treatment has left sperm science behind
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Great piece about the possibilities of technological innovation in reproduction. Closer to reality than when I spoke at
@ideacity
?
The Poly-Parent Households Are Coming
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Most health is outside of hospital. That's why mobile health is so important.
@Idasim
#bigadatamed
@StanfordMed
http://t.co/mjxHzRisSm
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Great coverage of emerging tech for male and female infertility.
@TrakHQ
@aaffttoonn
@StanfordMed
#MensHealth
Can a DIY fertility test help you plan when to have a baby?
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An amazing family. Such a joy to help. So happy for them.
"You are pregnant." It was what Jenny had wanted to hear for 14 long years. Stanford Fertility and Reproductive Health Services played a pivotal role, helping Jenny and her husband, Oscar, overcome roadblocks to pregnancy.
#Fertility
#ReproductiveHealth
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Work from our group looking at health risks in infertile men.
#MensHealth
"Increased risk of incident chronic medical conditions in infertile men: analysis of United States claims data"
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Let’s go, Mets! The lesson of Matt Harvey via
@WSJ
@jasongay
#MensHealth
This story may lead to more urologists.
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There seemed to be a trend for both men and women which increased after >1x per month.
#JSMJC
#JSMJC
@DrMEisenberg
can we say if there is a threshold
#marijuana
frequency of use that results in increased sexual activity?
@LJenkinsMD
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Frozen mouse testicles turned to sperm in a dish. More hope for cancer survivors.
@NatureComms
#MensHealth
http://t.co/r6q7FqJh5D
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Thx for mention
@ProfEmilyOster
Men, Those Tightie Whities Really Are Killing Your Sperm Count
#MensHealth
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The latest Silicon Valley Urology Times! Thanks to
@resolveorg
@renalandurology
@Uroweb
#urothelialcarcinoma
#blog
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Progress being made for both hormonal and nonhormonal targets. But it is hard to shut down a system that produces hundreds of millions of sperm every day.
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Percentage of all births to fathers over age 40
1972: 4.1%
2015: 8.9%
Thx for covering our work.
@stanfordmed
#MensHealth
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Great plenary talk by
@Craigni
teaching us about hormone therapy for
#infertile
men Data exists!
#MensHealth
#AUA15
http://t.co/iBMhBzreoL
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Diet associated with semen quality. Median sperm count of men with best diet: 167 M; Median count with Western (worst) diet: 122M
@JAMANetworkOpen
#MensHealth
Association of Dietary Patterns With Testicular Function in Young Danish Men
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Excellent point.
#Marijuana
use may be a marker of behavior/lifestyle. Although, increased sexual activity not necessarily
#riskysexualbehavior
;-)
#JSMJC
#JSMJC
@DrMEisenberg
the data did not account for multiple partners or protected sex practices. Might increased
#marijuana
use lead to an increase in
#riskysexualbehaviors
?
@LJenkinsMD
@jsexmed
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