Darius
@DariusBio
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Scientist in Comparative Genomics at Institute of Biotechnology, Life Sciences Center, Vilnius University, Lithuania
Joined March 2018
Finally published. Still SotA. TemStaPro: protein thermostability prediction using sequence representations from protein language models
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RT @TautvydasKa: Not all CRISPR-Cas systems cleave nucleic acids! Our recent study at @NAR_Open explores miniature Cas12m effectors, showca…
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RT @biorxiv_bioinfo: GTalign: High-performance protein structure alignment, superposition, and search #biorxiv_bio…
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At #NeurIPS conference to find new ideas on using AI in computational biology. Grateful to @BAFFScholarship for financial support!
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@duguyuan @sokrypton ESM-1b has a protein length limit (<1023 aa), thus, we use ProtTrans in our works. I'll guess we'll move to ESM-2 or your method soon 🙂.
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Origins and evolution of Rep-encoding ssDNA (CRESS-DNA) viruses - Developing an AI predictor to investigate thermostability of Cas9/Cas12/Cas13 proteins -
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RT @TautvydasKa: We are happy to report @Nature the cryo-EM structures of IS200/IS605-associated TnpB nuclease by Sasnauskas, Tamulaitiene,…
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Thermal stability varies in C2EPs. More than a half of the members of groups Cas12b, Cas12f1, Cas12f2, Cas12g, TnpB2 and TnpB-Kra have predicted temperatures of ≥50 ℃. In contrast, members of Cas12a, Cas9, and Cas13 groups might function at lower temperatures. #CRISPR
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