🎉 Exciting News! The Current Issues in Molecular Biology (CIMB) journal has achieved a new Impact Factor of 2.8 for 2023 and our CiteScore has risen from 2.4 to 2.9! 📊✨ A big thank you to our dedicated authors, reviewers, and readers for their invaluable contributions.

Mitochondria 🔬 evolved from ancient bacteria to key cellular players, impacting energy metabolism, signaling & disease. Their unique genome & role in health make them crucial in biomedical research. ⚡ #Mitochondria #CellBiology More :

Rapeseed 🌱 is a key oil crop, and double haploid (DH) technology accelerates breeding. Advances in DH production & genetic research enhance agronomic traits, improving yield & resilience. 🧬 #Rapeseed #PlantBreeding More :

Pre-eclampsia is a major pregnancy complication 🤰, linked to angiogenesis, inflammation & metabolic issues. More research is needed to improve early detection & reduce risks. 🏥 #MaternalHealth #PreEclampsia More :

Oxidative stress affects female reproduction, leading to infertility and pregnancy risks 🤰. Balancing antioxidants may help prevent complications like pre-eclampsia and IUGR. #Fertility #Pregnancy More :

🌿 CRISPR/Cas9 offers a promising way to reduce neurotoxin β-ODAP in grass pea, unlocking its potential as a resilient, protein-rich crop. Could gene editing make this underutilized legume safer for wider consumption? #CRISPR #GrassPea More :

🌱 Legumes offer a powerhouse of bioactive compounds with potential health benefits, from antioxidant properties to chronic disease management. Future research can unlock their full potential in sustainable nutrition! #Legumes More :

🧬 APOE haplotypes vary across global populations, influencing risks for neurodegeneration and cardiovascular disease. Ancestry-informed screenings could improve precision medicine approaches. #Genetics #APOE #Alzheimers #CardiovascularHealth More :

🧬 Genetic variants in glycogen metabolism genes may influence muscle damage in Late-Onset Pompe Disease (LOPD). More precise clinical scoring is needed to correlate genetic modifiers with disease severity. #PompeDisease More :

🔬 PTEN loss in HGPIN may indicate a higher risk of undetected invasive prostate cancer. Routine PTEN immunohistochemistry in biopsies could improve early detection and monitoring. #ProstateCancer #PTEN #Biomarkers More :

🧘‍♀️💡 Mindfulness-based therapy shows promise in PCOS! Reduced stress, improved well-being, and even DNA methylation changes in key genes. A potential holistic approach to managing PCOS beyond conventional treatments. #PCOS More :

📢 Call for Papers! Submit your research to Current Issues in Molecular Biology 🧬 Special Issue: Design & Synthesis of Bioactive Peptides & Molecular Conjugates for Targeted Drug Delivery 💊🔬 📝 Guest Editor: Dr. Ashmeet Singh 📅 Deadline: 31 July 2025

🧠🔬 The fascinating journey of microglia! From their debated origins to their key roles in CNS homeostasis & disease, research unravels their development & therapeutic potential. A deep dive into the life of these unique immune cells! More :

🧬💔 A novel nonsense TTN variant linked to severe dilated cardiomyopathy (DCM) found in a 57-year-old patient with a family history of DCM & sudden cardiac death. Highlights the need for genetic testing in at-risk individuals! More :

🏃‍♂️💓 Maximal exercise boosts endothelial progenitor cells (EPCs) in heart failure patients, enhancing endothelial repair & angiogenesis! No change in endothelial damage markers (CECs). Exercise = potential therapy! #HeartFailure More :

🔬 Pancreatic cancer remains the deadliest! 🚨 KRAS mutations in 80%+ cases. No early biomarkers yet! Small molecule inhibitors—natural & synthetic—hold promise for targeted therapies. 🧪 Future research is crucial! #PancreaticCancer More :

🧬🔬 DNA methylation in anxiety & depression: Flexible, not cumulative! COMT methylation correlates with acute symptom severity, not duration. Key insights into stress-epigenetics interplay! #Epigenetics #MentalHealth #DNA_Methylation More :

🔥 Dual targeting in AML! PU-H71 + BH3 mimetics (S63845, venetoclax) trigger apoptosis in AML, with FLT3/CD34 and CD117/CD11b profiles guiding therapy selection. Promising precision strategy! #AML #HSP90 #BH3Mimetics #TargetedTherapy More :

🧬 Structural diversity of mitochondria in cardiomyocytes revealed! 🏋️‍♂️ Lamellar cristae dominate interfibrillar regions, showing 2x higher membrane density. Tomography unveils crista remodeling pathways, linking form to function. #Mitochondria More :

🔬 Exosome analysis shows promise in #ProstateCancer diagnostics! PSA-expressing exosomes achieve 98.57% sensitivity, helping distinguish cancer from benign conditions. Challenges remain in standardization and cost for clinical use. More :

🧬 Molecular allergy diagnostics refine precision in detecting specific IgE to allergen components, enhancing diagnostic accuracy. Advances in singleplex and multiplex testing improve allergen profiling for personalized allergy management. More :