Biobot Analytics
@BiobotAnalytics
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Public health insights powered by wastewater | U.S. Nationwide Wastewater Monitoring Network:
Cambridge, MA
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We are monitoring the H5N1 virus situation closely and wanted to share what information we at Biobot have at the moment:
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Today, the Public Health Emergency (PHE) for COVID comes to an end. This will impact data being gathered and reported. Importantly,
#wastewater
data will be unaffected—becoming one of the best (and only) ways to understand disease burden, trends, and monitor for new variants. 1/2
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Wastewater concentrations for SARS-CoV-2, a leading indicator of COVID-19 trends, have been steadily increasing across the country over the past 11 weeks. As of January 6th, the national average concentration is the highest it's been since the Omicron wave in late 2021.
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Many of you have reached out in recent days inquiring about Biobot’s future with CDC NWSS. The contract Biobot held with CDC NWSS for the last few years was up for rebid this summer, and was recently awarded to Verily, an Alphabet precision health technology company.
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Biobot has identified evidence of the emerging BA.2.86 variant in recent
#wastewater
samples from several locations in the US, and retrospectively in samples dating back to Aug 3rd. Health departments in these locations have been notified.
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We remain committed to our vision and look forward to continuing our work with federal, state and local public health agencies, wastewater treatment plants, universities, and private companies all across the country to bring the vast potential of wastewater epidemiology to life.
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While we are disappointed with this news, we are incredibly proud of the work we’ve accomplished with CDC to date, and we know that this decision had nothing to do with our past performance. This is just the reality of how government contracting works.
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For those who follow our Covid-19 data dashboard (), we’re making a small change to our data updates. We will now update once per week on Mondays. We know many of you actively use our dashboard and we remain committed to bringing you this information.
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Biobot will continue to update our
#SARSCoV2
public
#wastewater
monitoring dashboard. Investing in continuous wastewater monitoring is more important now than ever. Refer to for US national, regional, county and variant trends. 2/2
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Our influenza A assay picks up H5N1, which is an influenza A virus, but does not distinguish between the different subtypes of influenza A (e.g. H5N1 vs H1N1).
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A benefit of sequencing SARS-CoV-2 in
#wastewater
is observing how the virus changes. Our data shows that a combo of new mutations, called FLip because they involve two L to F amino acid mutations, are increasing in the US.
#WBE
#populationhealth
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Updated Respiratory report 📢: Nationally, we are observing increases in influenza A and SARS-CoV-2 concentrations. Influenza B and RSV are holding steady and remain very low. Details here:
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Many people have reached about our decision to sunset the dynamic Covid-19 dashboard, and we’d like to provide more context👇🏼
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We are currently testing for influenza A in 6 out of the 8 states with positive dairy herds (Texas, New Mexico, Kansas, Idaho, Ohio, North Carolina).
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Our U.S. nationwide
#wastewater
data is now indicating we’re in a higher wave than any except the first Omicron one (Jan 2022). We’ll keep updating. Explore the data at
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The latest wastewater data shows sustained increases in Influenza A, RSV, and COVID-19 nationally, with Influenza B leveling and remaining low. You can learn more in our weekly report here (published every Tuesday):
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Our current assays do not distinguish between infections in humans versus animals that are shedding into the wastewater system.
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We will provide any additional information as it becomes relevant or available. In the meantime, you can read more about our influenza A data here:
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Biobot at the White House! It’s incredible to see the enthusiasm and support for wastewater epidemiology. A huge honor and milestone for our team and founders
@MarianaMatusG
@NewshaGhaeli
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Good news! Wastewater concentrations signal that we have likely made it past the seasonal peak for RSV and influenza, and that increases in COVID-19 activity are beginning to slow down. All three remain high, however, so be careful and plan accordingly!
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Happy holidays from Biobot! Wastewater data continue to show high levels of COVID-19, RSV, and Influenza A & B. We encourage everyone to take steps to keep themselves and their loved ones safe and healthy as we celebrate this holiday season.
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An update on our public data viz 📣 We are making some improvements to our data infrastructure over the next 30 days. In the meantime we will publish an update Friday 10/20 and again Friday 11/3, before going back to regular weekly updates.
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Wastewater data update📣 RSV remains high but we may be close to the seasonal peak. Meanwhile, COVID-19 is highest in the Midwest and Northeast, and influenza is rising across the US, driven primarily by influenza A. See our latest analysis here:
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For those following the Boston-area wastewater data, the trend we're seeing is not unique to Boston:
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New study in
@JAMA_current
: SARS-CoV-2 detection in clinical specimens. Finds ~30% of fecal samples with positive detection and: "Importantly, the live virus was detected in feces, implying that SARS-CoV-2 may be transmitted by the fecal route."
#COVID19
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Respiratory report update on H5N1: our assays detect influenza A, which includes H5N1. We're observing slight increases in flu A in the South, amidst declining respiratory virus activity nationally. Monitoring wastewater remains critical. Full report:
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📊NEW Data Analysis from our
#Epidemiology
and
#DataScience
teams: 👇
As of Mar 16, 2022, our nationwide
#wastewater
#data
has risen significantly for the first time since late Dec 2021—rising most rapidly in the Northeast region. 🧵1/3
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✨We’re thrilled to announce that Biobot Analytics has been selected for
@TIME
's list of the 100 Most Influential Companies of 2022!
#TIME100Companies
Explore here 👉
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The Biobot wastewater data indicates that nationwide Covid-19 levels remain low, with a 𝘀𝗺𝗮𝗹𝗹 𝘂𝗽𝘁𝗶𝗰𝗸 in about half of our 100 communities. During the Omicron wave, wastewater concentrations were increasing 100𝘅 𝗳𝗮𝘀𝘁𝗲𝗿 than now. Boston area below as example. 1/3
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Data collected at Boston’s
@MWRA_update
wastewater plant shows that the Boston area has passed its Omicron peak. But we’re not out of the woods quite yet: peak hospitalizations will come 1-3 weeks after the wastewater peak.
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How many people are infected with Covid-19? Sewage suggests that number is much higher than officially confirmed
Read about our work published yesterday in medRxiv
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Respiratory illness season is now in full swing across the US, with Biobot’s wastewater data showing active and increased co-circulation of RSV, influenza, and SARS-CoV-2 for the week of November 27. Check out the latest data here:
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Happy New Year 🎆 There is no data update for this week because our team took some well-deserved rest over the holidays. We will return to our regular schedule next week!
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We believe that at this point, there are other good resources for Covid-19 information from wastewater, and we encourage users who relied on our dashboard for decision-making to explore CDC NWSS, which offers data from many counties nationwide:
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What else is wastewater telling us? Nationally, there are signs we are nearing the peak of RSV transmission. On the other hand, Influenza A and B continue to rise steadily (this is second straight week Influenza A concentrations increased more than 40%)
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Biobot Cofounders, CEO
@MarianaMatusG
& President
@NewshaGhaeli
are name to the 2022
#TIME100NEXT
list!!! 🎉💪🦸♀️
The
@TIME
list highlights leaders shaping the future of business, entertainment, sports, politics, health, science, activism & more ➡️
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For the first time in 10 months (since early May 2022), our US national
#COVID19
#wastewater
concentration has dropped below 500 c/mL. While decreasing, levels are still more than 2x above those seen at this time last year and in 2020. 1/2
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Good news from this week’s wastewater update 📣 Nationwide data shows a decline in SARS-CoV-2, RSV, and influenza A concentrations. However, there's a slight increase in influenza B levels. Dive into the details here:
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Update from our
#COVID19
#wastewater
data—the Northeast remains highest w/ levels ~65% above the national average. The South is just above the national average having risen for ten weeks straight. These higher concentrations correspond w/ rising
#XBB
&
#XBB15
(shown as XBB*). 1/3
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We're thrilled to announce the continuation of our partnership with the
@CDCgov
on the National Wastewater Surveillance System, bringing
#COVID19
&
#mpox
#wastewater
analysis to hundreds of communities across the country.
➡️More info in the press release:
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Some good news from this week's wastewater update! National average concentrations for RSV, influenza A, and SARS-CoV-2 all declined. Influenza B is a bit of an outlier and remains elevated, especially in the Midwest. Learn more here:
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We're so proud to be recognized by
@Forbes
as one of the top women-led tech companies! Magic happens when a biologist and an architect come together to revolutionize public health! Congratulations to the Biobot team, which is 83% women and 100% badass!!!
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In collaboration with
@Ginkgo
,
@broadinstitute
,
@illumina
, &
@TwistBioscience
, we've successfully sequenced over 2,000 wastewater samples across all 50 states for SARS-CoV-2! This groundbreaking R&D effort represents the largest ww sequencing effort:
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Our Nationwide Wastewater Monitoring Network is LIVE on our website for the first time ever! We're publishing this data in the hopes of providing even more stakeholders the opportunity to tap into the benefits of WBE. GitHub repo coming soon.
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Wastewater continues to bring good news this week: the most recent data show that RSV, influenza, and COVID-19 activity in the US are on the decline. Even with these encouraging signals, however, wastewater concentrations for all three remain high.
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We remain committed to supporting our communities through our Respiratory Reports, which analyze wastewater and clinical data for influenza and RSV, and will soon include COVID-19 data.
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Wastewater update: Our weekly reports now feature Flu and RSV wastewater concentrations segmented by region (in addition to national concentration)! See the latest data here:
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Biobot's wastewater data show that SARS-CoV-2 and influenza continue to decline across the country. While RSV activity has increased slightly, the trajectory for all three major respiratory viruses is still downward. Learn more in our weekly report:
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As of June 1, our nationwide
#COVID19
#wastewater
concentration has 𝘀𝘂𝗿𝗽𝗮𝘀𝘀𝗲𝗱 𝘁𝗵𝗲 𝗗𝗲𝗹𝘁𝗮 𝗽𝗲𝗮𝗸 (Sept. 2021). We now have a national average of 824 copies/mL, which is 68 c/mL higher than the Delta peak of 756 c/mL.
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Good news! Wastewater shows declining RSV, influenza B & COVID-19 nationwide. Influenza A has plateaued. Read more here:
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Wastewater data update 📣 Nationally, RSV concentrations are down (!) 13% over the previous week. However, influenza concentrations continue to rise, with influenza A highest in the Northeast and influenza B highest in the South. Learn more here:
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We are THRILLED to announce our Series A financing!🚀
With this funding, we are excited to expand our work in cities & launch our enterprise solution.
Shoutout to our amazing team, partners, and everyone who believes in the power of wastewater epi!
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Biobot & wastewater epidemiology on the front-page of
@nytimes
! We need more accessible wastewater data to monitor outbreaks now: “make more data available, faster” Read more & join our mission:
Tracking the virus in wastewater is helping some U.S. cities and hospitals respond to the most recent wave of the coronavirus, but a more coordinated national effort is needed, experts say.
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Updated Respiratory report 📣: National SARS-CoV-2 concentrations continue to increase, while influenza A & B and RSV remain stable and low. Details here:
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This decision does not mean we think Covid-19 is no longer a risk to communities and individuals. But rather that we feel the resources provided by the CDC cover much of what our dashboard did.
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Our national average ww concentration is 𝟯𝟮% 𝗵𝗶𝗴𝗵𝗲𝗿 𝘁𝗵𝗮𝗻 𝘁𝗵𝗲 𝗗𝗲𝗹𝘁𝗮 𝗽𝗲𝗮𝗸 (1075 vs. 814 c/mL). All regions are rising—the South is highest at 1228 c/mL. Stay tuned for more updates.
Our U.S. nationwide
#wastewater
data is now indicating we’re in a higher wave than any except the first Omicron one (Jan 2022). We’ll keep updating. Explore the data at
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We are correcting this week’s respiratory report: Nationally, influenza A & B, and RSV wastewater levels declined while SARS-CoV-2 increased. Overall, national respiratory activity remains low. Details here:
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📣 Milestone Alert 📣 Biobot has officially analyzed wastewater from over 1,000 unique sites! That’s a lot of GDP (Gross, Domestic Poop 😀)
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Help "COVID Down the Drain" advance in
@statnews
#STATMadness
! We are proud to be nominated with so many others doing groundbreaking work in biomedicine to support public health, with our partners
@BrighamWomens
@PeterRChai
&
@MITdeptofBE
. Vote here:
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Biobot’s Wastewater Monitoring Platform is on
@TIME
's list of the Best Inventions of 2022 in the Social Good category!! ✨ We are honored to be recognized in this way—
#TIMEBestInventions
#wastewater
#publichealth
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Data as of December 16th show a significant increase in influenza across the nation, with a 42% increase in influenza A concentrations. The Northeast is seeing the most severe increase for both Influenza A and B, as well as RSV.
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Great news from this week’s wastewater update 📣 Nationwide data show that SARS-CoV-2, RSV, and influenza A and B all have declining wastewater concentrations. Check out the details here:
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Given the high level of interest in the
#MonkeypoxVirus
, Biobot is collaborating w/ Marc Johnson
@SolidEvidence
from
@Mizzou
for early testing. So far all tested samples from 5/5-5/20 have been negative. This assay is still under development—we’ll provide updates as we progress.
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Updated Respiratory report 📢: Nationally, we are observing increases in SARS-CoV-2 concentrations, while influenza A & B and RSV are decreasing and remain low. Details here:
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We welcome
@MITdeptofBE
grad Claire Duvallet
@cduvallet
to the Biobot team as our first data scientist!
We’re so excited to work with such a superstar. Welcome Claire!!!🥂🎊👏🚀🏆
#TheFutureisFemale
#WomenInSTEM
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Great example of early variant detection via
#wastewater
monitoring. New variant of concern,
#XBB15
, was detected in Hawaii wastewater before any clinical cases. This highlights the importance of continued wastewater surveillance to help build proactive public health systems.
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Today's public viz update is live for the week of Oct. 30! The data includes national & regional averages from 150+ counties, representing 250+ sites. More info coming soon for wastewater treatment plants wanting to join the Biobot Network & share data!
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Join us in celebrating Biobot CEO/Cofounder,
@MarianaMatusG
, who received the Distinguished Mexican Award from the Secretaria de Relaciones Exteriores
@SRE_mx
last night 🇲🇽! She was honored for her outstanding professional career as a scientist, entrepreneur & business leader 👏🏼
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Wastewater update! National average wastewater concentrations for SARS-CoV-2 declined since last week. Influenza A concentrations declined slightly while influenza B activity continues to increase. RSV wastewater concentrations remain low. Read more here:
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For the 1st time in 6 months, Biobot’s US national
#SARSCoV2
#wastewater
concentration is close to levels seen at this time in the past 2 years & for the 1st time in a year, levels are below those seen in 2020. The current avg is ~40% lower than in 2020.
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The most recent wastewater data show that SARS-CoV-2 and influenza activity ticked up slightly, while RSV declined. Despite these small fluctuations week over week, the trajectory for all three major respiratory viruses continues downward. Learn more:
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The FLip mutations are evolving from XBB variants and appear to allow the virus to more easily bind to human cells. This could make it harder for antibodies to fight off infections with variants that have these mutations.
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Biobot's most recent wastewater data shows that RSV season is nearing its end! However, influenza and SARS-CoV-2 concentrations remain elevated, and actually increased in some parts of the country. Learn more in our weekly report:
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Updated respiratory report 📣: Nationally, influenza A & B, and RSV wastewater levels decline while SARS-CoV-2 holds steady. Overall, national respiratory activity remains low. Details here:
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As a reminder, our Covid-19 data viz is updated at the beginning of each week and our respiratory risk report is published every Tuesday.
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📣We’ve expanded our partnership with the
@CDCgov
through the National Wastewater Surveillance System (NWSS) to include monkeypox analysis. The data will help track
#monkeypox
prevalence & spread to inform public health responses.
Read the press release 👇
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Our national
#wastewater
dashboard is updated!👉 Check out to explore the latest
#COVID
-19 trends from 153 different sites across 29 states in the US.
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16
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Biobot Analytics can now detect the B.1.1.7 (UK)
#COVID19
variant in wastewater. Read more about our work with SMART and what this advancement means for communities like yours:
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Great to see Biobot's wastewater data play a crucial role in the CDC's response to emerging infections. This new paper shows how wastewater analysis detected mpox virus in communities with just one known case, demonstrating remarkable sensitivity.
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Biobot is officially NIH funded!
Amidst hard work, countless samples of stool and urine and manholes comes the most excellent news during this
#covid19
pandemic. Congrats
@MarianaMatusG
@BiobotAnalytics
@NewshaGhaeli
@ejalm
and all! One of my favorite collaborations ever, now
@NIDAnews
@NIH
funded!
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📉Update from our
#COVID
#wastewater
data—the nation continues to see a marked drop in ww concentrations! The national average has now decreased for three weeks in a row, and is ~6x lower than the Omicron peak, which happened around this time last year.
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6
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Super excited that our preprint describing methods to detect
#SARSCoV2
in sewage and infer population-wide prevalence is out on
@medrxivpreprint
!
We’re taking wastewater epidemiology all the way from sewage to estimated
#COVID19
cases (💩➡️🕳️➡️😷📊).
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31
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Late last week, a continued national increase in concentration of COVID-19 was revealed in
#wastewater
, led by the Midwest. Overall levels are still lower than previous waves and new data released tomorrow may shed light on this evolving summer wave.
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12
56
Wastewater update 📣 (samples were delayed this week because of the snow!): nationally, influenza A and RSV are on the decline, influenza B activity is nearing its seasonal peak, and SARS-CoV-2 remains consistent. Read more in our weekly report:
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13
56
Preliminary results are in: we can monitor influenza in wastewater! Our new flu pilot program underscores wastewater epi's role in helping monitor outbreaks of all kinds. Check out the newest press release:
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There’s been a lot of interest recently in the "stealth" Omicron subvariant BA.2.
Update from the sewers: As of Jan 13, BA.1 is still the dominant Omicron subvariant in wastewater at all our sites. We are beginning to see some BA.2 (<1%). We'll keep sequencing and updating
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16
55
📣Our
#COVID19
#wastewater
dashboard is now tracking XBB* subvariants XBB.1.9 & XBB.1.16, both growing in proportion across the US. While XBB.1.9 proportions are higher across all regions, XBB.1.16 has grown most quickly in the Northeast per our data.
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22
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#wastewater
levels remain relatively stable, which is a distinct departure from declining trends seen in the past two years during February. The national avg is ~60% higher than it was at this time in 2022 & is almost 2x what it was at this time in 2021.
Update from our
#COVID19
#wastewater
data — the national average is slowly declining but remains in a high plateau. Current levels are above those seen at this time in 2021 & 2020, mirroring the general high plateau pattern seen throughout most of 2022.
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14
53
NEW Biobot mpox
#wastewater
monitoring dashboard for the US is now live! Check out mpox wastewater data at the regional level w/ percentages of positive detections per week starting in Oct ‘22. Compare regional ww data w/ nationwide
#mpox
case data at
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9
53
This
#ValentinesDay
, our hearts are more than just flushed with love—they're overflowing with gratitude for YOU! Our incredible community and partners are the true heartbeat of our mission toward a safer, healthier world. Thank you for being a part of our story! 💙🌎
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7
51
For the 2nd week in a row, our
#COVID19
#wastewater
data has risen. The Northeast, Midwest & South are higher than the national average. The Northeast & Midwest are above their respective Delta peaks and the South & West are both lower than theirs. More at
4
28
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Update from our
#COVID19
#wastewater
data — the national average is slowly declining but remains in a high plateau. Current levels are above those seen at this time in 2021 & 2020, mirroring the general high plateau pattern seen throughout most of 2022.
3
24
53