Beau Bosko Toskich, MD FSIR
@BeauToskichMD
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Professor of Radiology, Director of Interventional Oncology, Mayo Clinic Florida
Joined September 2023
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岡田監督
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#AASLD
#HEPATOLOGY
cover article:
Overall survival significantly higher in patients with intrahepatic
#cholangiocarcinoma
treated with the addition of
#radioembolization
: 21.7 months vs. 15.9 months, HR = 0.59, p = 0.049. 🧩
RCT even feasible?
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Congratulations to the
@bostonsci
interventional oncology team and
@riadsalemIR
on another successful
#Therasphere
Advanced User Meeting! Uncanny how much
#radioembolization
has evolved with your unwavering support and drive to improve the lives of our patients.
#Y90
#HCC
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#TRANSPLANTONCOLOGY
helps select patients with
#ColonCancer
liver mets.
#EPOCH
showed superior disease control by adding
#Y90
to systemic therapy.
#TARE
does not compromise the hepatic artery.
If
#MELD
exception becomes reality, time to discuss
#BRIDGING
.
#windowofopportunity
🧩
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High specific activity matters in current
#Y90
#TARE
#HCC
practice. Tumor microdose environment should be further investigated. 🧩
#limitedseats
#legolasparticle
#brighterlightbulbs
#radiationpermicrosphere
What specific activity (aka radiation per microsphere) do you choose when treating solitary
#hepatocellularcarcinoma
<8 cm with ablative
#Y90
#TARE
?
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Congrats to Prof. Pierce Chow and IMbrave050 investigators. Atezo/bev after curative intent treatment for high-risk HCC improves RFS. We are officially in the adjuvant HCC era 🧩
#HCC
#hepatocellularcarcinoma
#Immunotherapy
@dukenus
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Thank you
@thegestgroup
and esteemed faculty for a comprehensive and informative update on the state of local therapy for hepatocellular carcinoma. Congratulations to all on another successful virtual summit!
#interventionaloncology
#hepatocellularcarcinoma
#livercancer
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Another fantastic
#MayoClinic
HPB Cancer Symposium: ✅️
Thank you again
@GIcancerDoc
@MiteshBorad
@danduda9
and
@Seanpcleary
for the invitation!
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@bsc_io
@ChrisDMaloneVIR
@WUSTL
@MIRimaging
@WUSTLmed
@SitemanCenter
Congrats Dan and Chris on launching us into a new era of combination
#Y90
and
#Immunotherapy
for
#HCC
.
#ROWAN
#RELEVANT
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Congratulations to Dr. Wendy Sherman and
@DoctorQMd
for a fantastic Mayo Clinic Advances in Neuro-Oncology Symposium! It was a pleasure to present on emerging endovascular therapies for brain cancer. Exciting times.
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What specific activity (aka radiation per microsphere) do you choose when treating solitary
#hepatocellularcarcinoma
<8 cm with ablative
#Y90
#TARE
?
High specific activity
36
Low specific activity
1
Doesn't matter
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Great article on radioembolization for
#LiverCancerAwarenessMonth
by our
@MayoClinic
colleague Dr. Jeremy McBride in Eau Claire. Radioembolization is now an
@US_FDA
,
@AASLDtweets
,
@NCCN
, and
@BCLC_group
supported therapy for
#HCC
.
October is
#LiverCancerAwarenessMonth
. Consider sharing this article to raise awareness of
#LiverCancer
and the latest treatments for the disease.
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Immunotherapy alone with
#STRIDE
for
#HCC
improves survival. Combining with current
#Y90
TARE practice in the
#ROWAN
study is a timely and
#RELEVANT
next step. 🧩
Four-year Overall Survival from the HIMALAYA Study of Tremelimumab + Durvalumab in Unresectable Hepatocellular Carcinoma
STRIDE significantly improved overall survival and demonstrated a durable long-term survival benefit.
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I applaud ESMO for recognizing the adjunctive value of real-world evidence. As cancer care becomes more personalized, powering legacy trial design becomes more challenging. Addressing this will require innovation and an open mind.
🔥off the press: ESMO Guidance for Reporting Oncology real-World evidence (GROW)
@Annals_Oncology
👉RWD are gaining increasing interest to complement clinical trials
👉Here, we provide detailed recommendations for reporting RWE studies in oncology
@myESMO
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@ArndtVogel
@EASLnews
@ILCAnews
It all comes down to angiosome mapping
#radioembolization
. Nearly half of patients recur in 2 years without transplant, commonly out-of-field. Combination for all?
#noearlystagehcc
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Join
@thegestgroup
tomorrow at the Hepatocellular Carcinoma Virtual Summit for a stirring and relevant program driven by global experts in the management of liver cancer.
#interventionaloncology
#interventionalradiology
#hepatocellularcarcinoma
#hcc
#livercancer
Session 2 of the HCC Virtual Summit will cover Hepatocellular Carcinoma Therapeutic Intersections: Evidence and Experience.
Join Dr. Julie Heimbach, Dr. Robert Lewandowski, Dr. Daniel Brown, Dr. Sarah White, Dr. Edward Kim, and Dr. Umair Majeed this Saturday (10/7/2023).
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Abscopal
#cryoablation
for
#immunotherapy
refractory infiltrative
#hepatocellularcarcinoma
resulting 5 year complete response. Downstaged to transplant with
#completepathologicnecrosis
.
#interventionaloncology
and
#immunooncology
#timetocombine
🧩
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Emerald-1 is positive. How will the data readout impact your MDT?🧩
#HCC
#AstraZeneca
#Durvalumab
#TACE
#combinationtherapy
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Curative
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Palliative
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@AHPBA
and
@ASTSChimera
driving the vision for liver transplant in patients with hepatic metastatic colorectal cancer.
#Transplantoncology
is here.
Thank you
@DrTBB_liverdoc
,
#Mariamajelladoyle
,
@sapisochin
,
@theliversurgeon
for the invitation!
#livertransplant
#coloncancer
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@roblookstein
@MountSinaiIR
@MayoRadiology
Was a pleasure to visit the amazing Mount Sinai IR team! Thank you again.
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@SLU_VIR
@MayoClinic
@keithppereira
@vaheesanIR
@SIRspecialists
@SIRRFS
@NorthwesternIR
Thank you again for the invitation, Keith! Was a pleasure to meet the awesome
@SLU_VIR
team.
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@djabdo_md
Why reduce specific activity for higher particle number administrations when treating with ablative intent?
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@TorzilliGuido
@SSATNews
@IASGO_1988
@IHPBA
@EAHPBA
@APHPBA2023
@Aicep4
@SIC_chirurgia
@HUNIMED
@HumanitasMilano
Complimenti, Guido!
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@djabdo_md
Why not increase dose to maintain both high specific activity without compromising desired particle # when ablating expendable volumes of liver?
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#Abscopal
#ablation
events are rare, but safe and impactful. When should we consider as salvage? What % response would make it standard-of-care in patients with limited options?
#cryoablation
#radioembolization
#pulsedelectricalfield
#histotripsy
#viraloncolysis
#IRE
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