ApoE Discoveries
@ApoEdscvr
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Here to share advances in Apolipoprotein E research and therapeutics! š§ Please tag and follow if interested in #ApoE #APOE šš¼ Account by @ytquiroz
Joined February 2020
RT @yassinelab1: Is making brain HDL by inducing ABCA1 a viable strategy for APOE4 Alzheimer's? Our talented researcher Dr. Shaowei Wang haā¦
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APOE4 and sedentary lifestyle synergistically impair neurovascular function in the visual cortex of awake mice
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RT @AnderleSilvia: My first first author paper is finally out! š Check it out and let me know what you think š
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ApoE3 R136S binds to Tau and blocks its propagation, suppressing neurodegeneration in mice with Alzheimerās disease: @NeuroCellPress
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RT @alzforum: Scientists may have discovered why ApoE4 causes Alzheimerās disease and ApoE2 prevents it. Hint: the reasons are different. @ā¦
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Cognitive Intra-individual Variability in Cognitively Healthy APOE Īµ4 Carriers, Mild Cognitive Impairment, and Alzheimerās Disease: a Meta-analysis | Neuropsychology Review
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APOE Īµ4āassociated heterogeneity of neuroimaging biomarkers across the Alzheimer's disease continuum - Mares - Alzheimer's & Dementia - Wiley Online Library
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AAVrh.10 delivery of novel APOE2-Christchurch variant suppresses amyloid and Tau pathology in Alzheimerās disease mice: Molecular Therapy
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RT @CellCellPress: Now online! Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipiā¦
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Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes: @CellCellPress
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RT @jungsukim77: "Consistent with prior reports,34,41 WT and E4 animals did not display significant differences in neuronal activity and weā¦
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Microglia depletion reduces human neuronal APOE4-related pathologies in a chimeric Alzheimerās disease model: Cell Stem Cell
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RT @KaishaMeyer: Happy to share a preprint of my manuscript exploring the neurodevelopmental role of APOE4 in brain organoids š¤ stay tunedā¦
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Deletion of miRā33, a regulator of the ABCA1āAPOE pathway, ameliorates neuropathological phenotypes in APP/PS1 mice - Tate - ā¦@alzdemjournalsā© Alzheimer's & Dementia - Wiley Online Library
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RT @jungsukim77: Now that people are talking more about microRNAs, thanks to the Nobel Prizeš Deletion of miR-33, a regulator of the ABCA1ā¦
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The effects of APOEe4 allele on cerebral structure, function, and related interactions with cognition in young adults - ScienceDirect
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Alzheimerās disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model: Neuron
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