Annie L Hsieh
@AnnieLHsieh2
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Neuro-Oncology Attending @MGH | Postdoc @ B. Sabatini Lab & M. Haigis Lab | Metabolic Regulation of Neurogliomal synapses | Physician-Scientist Mom
Boston, MA
Joined August 2022
🎉Exciting news! Our latest work on Glioma-Innervating Neurons has just been published in PNAS!🔗 Read the full article here: A huge thank you to my co-mentors @blsabatini, @HaigisLab and co-authors. @MGHNeuroOnc @MGHCancerCenter @MGHNeurology
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RT @RogerJDavis1: Rhodoquinone carries electrons in the mammalian electron transport chain: Cell
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RT @BWHNeurology: Annie Hsieh, M.D., Ph.D., et al., published “Widespread neuroanatomical integration and distinct electrophysiological pro…
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Thank you, Nino, for organizing this outstanding in-person faculty meeting, bringing together clinicians and scientists to brainstorm the best strategies for integrating MGB CTNS. It was a fantastic opportunity to learn from each disease workgroup and connect with colleagues.
Getting ready for the inaugural Center for Tumors of the Nervous System (CTNS) event at the Harvard Club today! Excited to hear from all of our speakers. #CTNS #HarvardClub
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Super interesting!!
Congrats to @HaoChen_neuro and the team on his paper on Hao-Fountain syndrome. A fantastic collaboration with @AzadBonni and Cole Ferguson. @WashUNeurosurg
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Excited to be at the Keystone Conference on Cancer Neuroscience and tumor microenvironment! Inspiring talks and a stunning venue at Fairmont Banff Spring fostering innovation and collaboration. #KeystoneConference #CancerNeuroscience
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@blsabatini Thank you so much, Bernardo, for your kind support and encouragement! I’m truly thrilled to see the paper published and grateful for your guidance along the way.
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We are thrilled to share that Harvard Medical School has featured our research in their latest news update.
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Congratulations @wenyalindabi and team!! Very important insights in the field of IDH-mutant astrocytoma.
Congrats @wenyalindabi and team on an important paper on IDHmut astrocytoma 🚨 New insights on IDH-mutant astrocytomas. Background: Molecular features like CDKN2A/B loss already enhance glioma grading and prognosis. But for histologic Grade 2/3 IDHmut astrocytomas, molecular markers to refine survival predictions are lacking. Study: Analyzed 998 adult IDHmut astrocytoma patients (1989–2020) using public datasets + academic medical centers. Researchers integrated histologic grades, CDKN2A/B loss, and focal gene amplifications for risk stratification. Findings: •Grade 2/3 tumors with intact CDKN2A/B & no amplifications had longest survival (OS ~205.7 months). •Grade 2/3 tumors w/ CDKN2A/B hemizygous loss or amplifications had similar survival to Grade 4 tumors (OS ~80-91 months). •Grade 4 astrocytomas w/ CDKN2A/B loss had worst prognosis (OS ~31-32 months). Key Insight: CDKN2A/B hemizygous loss + focal amplifications identify a subset of IDHmut astrocytomas with intermediate survival, independent of histologic grade. Impact: Combining molecular features w/ histology refines classification + prognosis for IDHmut astrocytomas, paving the way for more tailored treatment approaches. #Glioma #NeuroOncology #PrecisionMedicine @MGBneurosurgery
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Thrilled to see such promising results for DIPG treatment! Huge congratulations to Michelle and the team for this breakthrough! #DIPG #NeuroOncology
#CARTcells for #DIPG #DMG clinical trial (1st arm) results are out today. Full Tweetorial coming, but first want to share the story of a patient whose #DIPG has disappeared for over 3 years. It is a milestone and moment of hope on a journey filled with so much grief. “There’s a lot of loss that led to this research,” Drew’s dad said. “I hope those families know that this success is because of them.”
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RT @TVKamath: The first piece of work from my PhD has now been uploaded to biorXiv! Short 🧵below:
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RT @AlexandrCaron: Check out our Spotlight in @Cell_Metabolism regarding @AnaDomingosLab’s recent paper in @Nature uncovering that NPY prod…
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Congratulations, Dr. Carter!!
I want to thank the many friends, colleagues, collaborators, faculty, students, residents, post-docs, and mentors from @harvardmed @MassGenBrigham @MGHNeurosurg @MGBneurosurgery @MassGeneralMDs @UCSDNeuroSurg @UCSDHealth @HopkinsNsurg @HopkinsMedicine @BYU @CNS_Update @AANSNeuro who have inspired me along the way and provided incredible support during my academic journey. I'm looking forward to joining @theNAMedicine community and continuing to serve our larger goals of improving human health for everyone, everywhere!
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Congratulations Marcia!!! Such an amazing news. Well deserved!
Congratulations to the wonderful @HaigisLab on her election to the National Academy of Medicine 💪🏼 Well deserved to a great scientist, mentor, friend and role model
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RT @MJWu_TW: Congratulations @davetingmgh @EunaeYou476 on their latest work in @CellCellPress, showing how repeat RNA elements in extracell…
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Thrilled by the inspiring journeys of Nobel Laureates! 🌟 This year is extra special with a Nobel Prize winner at our institution. Feeling incredibly honored and privileged. Congratulations, Dr. Ruvkun and Dr. Ambros! @MGHMedicine @MassGenBrigham
BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
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