Associate Professor, Neuroradiology - Director, CU CSF Leak Program - University of Colorado Anschutz Medical Campus - Alumni: UCSF -
#CSFLeak
#NeuroRad
Lumbar puncture with a ventral through and through 1-2 mm dural tear resulting in years of leak suffering for this patient. Very challenging dynamic CTM and surgical localization - a good reminder to please use the smallest, non cutting spinal needles possible if an LP is needed
While disabling and challenging to find, CSF venous fistulae "can" be beautiful - check out this volumetric rendering of a CT dynamic myelogram demonstrating a fistula arising from a perineural cyst at T10-T11
#SIH
#CVF
#SIH
due to a dural tear after chiropractic manipulation. MRI: sag and an extradural collection (green). Dynamic CT myelography: ventral dural defect (yellow) 2/2 osteophyte (red). We took a TRANSDELTOID approach to the ventral epidural space for fibrin glue patch.
@AsheshThaker
We all love seeing the
#CVF
drain into the paraspinal segmental vein for that "classic" look, but don't forget about the internal epidural venous plexus! Looks like a "dot" on axials and can be easily overlooked but coronals can be your friend.
Spent Black Friday performing Colorado's first endovascular occlusion of a CSF venous fistula with Dr. Adam Schwertner at
@DenverHealthMed
. Grateful to
@WBrinjikji
for pioneering this technique for our patients.
#SIH
Delayed MRI myelography shows its value in a patient with orthostatic headache, very subtle intracranial MRI findings (albeit noncon) and negative dynamic CT myelography x2. Delayed MR myelography demonstrated a slow leak from a right T9-T10 perineural cyst!
#SIH
#CSFleak
Phase 2 feasibility testing and phantom scanning prior to clinical implementation of our dynamic CT myelography patient positioning device. My goal is to increase reproducibility, sensitivity, and patient safety in dynamic CTM.
#SIH
Happy to share our new
@AJNR
paper describing a novel positioning device for dynamic CTM CSF leak/fistula localization.
Thank you to everyone who supported me and continue to support my
#CSFleak
obsession, particularly
@jodytanabe
and
@CUneurorad
.
A remote labor epidural dural puncture was the cause of our patient's new daily persistent headache diagnosis over a decade later! Please always obtain a thorough history of any needle in your patient's back, no matter how remote:
#CSFleak
#PDPH
I am very happy to share our manuscript detailing our algorithm for workup/treatment of
#SIH
, emphasizing the importance of a multidisciplinary approach to care for our
#CSFleak
patients and a pathway for "imaging negative" individuals suffering from orthostatic headache.
New
@AJR_Radiology
Accepted Manuscript:
"Algorithmic Multimodality Approach to Diagnosis and Treatment of Spinal CSF Leak and Venous Fistula in Patients With Spontaneous Intracranial Hypotension"
By Dr
@AndrewCallenMD
& team
@CURadiology
An important
#SIH
paradigm: the leaking patient with a dorsal epidural collection without ventral component. This young patient with no ventral osteophytes or ventral collection was found to have a fast lateral leaking cyst on decubitus dynamic myelography, treated with fibrin.
This is part of what motivates me to find leaks in my
#SIH
patients. The validation of their symptoms with irrefutable imaging evidence after sometimes years of being told they are crazy.
It's a good historical moment to reflect on the fact that M.S. was commonly called a "hysterical paralysis" conversion disorder until neuroimaging made it possible to see the lesions.
In this study we tried to understand which patients with a suspected
#csfleak
who do not meet ICDH-3 criteria for
#SIH
still benefit from epidural patching.
I’m very proud to have played a small part in this important study led by
@DrIanCarroll
We have been finding several
#CVF
after flipping the patient contralateral decubitus after a single injection during dynamic CTM. While probably slightly less sensitive than a second bolus, it is nice to save the
#SIH
patient a second puncture or contrast bolus if you can:
15 hours of flying to be in Hawaii for 48 hours, but was still one of the best trips for me- such an amazing meeting - I learned so much from so many amazing people in this field. Thank you
@WouterSchievink
for inviting me to speak.
@spinalCSFleak
#CSFleak
@DrIanCarroll
Cord herniation or arachnoid cyst? A common conundrum. Dynamic CTM can help! Arachnoid cysts will often fill in on delayed imaging, so obtaining early dynamic imaging is key to making the diagnosis, outlined beautifully in this case:
@NeuroRadSam
1. Spinal elastance correlates with specific brain MRI changes in
#SIH
2. Bern score maintains predictive validity on dynamic CTM (even when excluding pachymeningeal enhancement!)
3. Opening pressure (again) is a poor predictor of finding a leak/fistula
@WendeNGibbs
‘Left frontal encephalomalacia likely reflecting an old infarct.’ I don’t like using ‘chronic’ because it means old and ongoing, but I know this is an unpopular opinion.
What is a 'good clinical story' for SIH, especially w/ CVF?
40% of our cohort lacked a 'classic orthostatic headache.'
We used cluster analysis to reveal distinct clinical and imaging patterns. Read our open-access study here:
It was so fun hosting
@SharathKumarGG7
this week in our CSF Leak Program. His passion to care for Indian patients suffering from CSF Leaks is self evident. India is so lucky to have such a dedicated physician!
Thank you
@spinalCSFleak
for sponsoring his trip!
It was an honor to help highlight some of the important papers in
#CSFleak
,
#SIH
, and
#PDPH
over the past several years in
@HeadacheJournal
- check our our open access review here:
🗓️Save the date!🗓️ Join
@AndrewCallenMD
and the Spinal CSF Leak Foundation for a unique one-day hybrid symposium Nov. 11th bringing patients and providers together to learn from one another. Stay tuned for registration info!
#BridgingtheGap
#becauseyourduramaters
We are so excited to welcome Dr. Samantha Petrucci MD PhD (
@NeuroRadSam
) to
@CUneurorad
and the CU CSF Leak Program. Dr. Petrucci trained at UCSF and has extensive experience in caring for patients with
#CSFLeaks
.
Cross-institutional collaboration with
@DukeRadiology
led to rapid, expedited care for a
#CSFleak
patient this weekend. Our patients do better when we work together!
Spinal CSF Leak Canada is very pleased to announce that
@AndrewCallenMD
has joined the organization’s medical advisory committee. Welcome aboard Dr. Callen and thank you for your dedication.
True clinical progress is driven by our technologists and nurses, the real stars behind the scenes. Their dedication is the secret to success. I'm just lucky to be part of this incredible team!
@CUneurorad
@uchealth
We are working hard to put together a unique program with an amazing lineup of both physician and patient speakers to build on last year’s event. More information coming soon!
Announcing our 2nd annual Bridging the Gap conference! This year’s theme is “Past, Present, and Future.” This TWO-DAY in-person & virtual conference will take place November 2-3, 2024, and will be free for patients. We'll be sure to let you know when registration opens!
Amidst the buzz re: physician burnout and low job satisfaction, try to remember the brighter side. Yes, we face administrative burdens, high caseloads, and systemic challenges. But, we're granted a unique privilege: to infuse our daily work with profound purpose. 1/2
Happening now!
@EmmaSechrist
presenting her abstract (and accepted publication!) studying a potential association of
#CVF
with spinal osteoarthritis
@The_ASSR
So proud of Jen Mackenzie for sharing her story and teaching us about what it means to recover from a
#CSFLeak
. Her lecture really encompasses what this day is all about.
Thank you
@SimyParikh
and
@TJUHospital
for the invitation to speak on
#CSFleak
diagnosis and treatment! It was my honor and privilege to visit one of the top headache centers in the country.
Kudos to
@MarkMamloukMD
for leading this project, highlighting the exponential growth of interest and understanding of spinal CSF leaks in the last few years.
@TheAJNR
in particular has published numerous wonderful contributions to the literature.
Thank you
@MohitAgNeurorad
and
@thecortexclub
for inviting me to join such a great organization dedicated to radiology education! (Olive likes the shirt too 🐶)
The best part of
#ASNR
is spending time with the people you look up to in your field. A lovely dinner with lovelier people. Thank you
@LindaGr4510
for organizing.
Congratulations to
@EmmaSechrist
for winning the
@The_ASSR
Louis A. Gillula, MD Mentor Award for her fantastic
#CSFleak
project! I am so excited to see what great things you will do in your career!
When you think of dural venous sinus thrombosis, compressive ischemic brainstem injury, spinal siderosis, SAH, pial vascular enrogement, dural calcifications and calvarial hyperostosis, do you think of
#SIH
/
#CSFLeak
?
@vinil_shah
@williamdillonmd
2/2 I am reminded of this whenever I witness families celebrating a birthday in the hospital cafeteria. Life is precious and we are so fortunate to be partners in our patients' most vulnerable moments.
1 of my favorite memories from training: I came in early to find my attending - a world expert- preparing for a multiD conf reading a review on a disease he was the first to describe. I asked why, he said “I don’t know the most about this, I just had the most questions about it”
Please join us in person or virtually for this unique, free CME event featuring incredible patient lectures as well as didactic lectures from physicians across the country on all aspects of CSF leaks!
SNEAK PEEK: Our upcoming “Bridging the Gap” conference on Nov 11 features the voices of patients as well as providers. In this clip, Sarah talks about the importance of understanding that spinal CSF leak is more than just a headache.
Register:
Does your institution use a standardized reporting template for brain MRIs looking for signs of
#SIH
/
#CSFLeak
? We found that the use of a template decreased the proportion of patients inappropriately classified as "negative" or low probability.
We know the false localizing sign in
#SIH
posterior to C2 due to anatomic communication of the epidural space and posterior spinal soft tissues. This patient has a "reverse" false localizing sign, presenting after suboccipital crani with leaking duraplasty into epidural space!
It was so great to have
@BhavyaRShahMD
come speak to us about his incredible HIFU program and research. I was particularly grateful for his advice on creating a patient-facing clinic as a radiologist, very apropos as our
#SIH
clinic has opened this week!
Before he departs for a faculty position at
@CURadiology
, we'd like to share
#research
authored by Dr. Andrew Callen,
#RadRes
Class of 2019. Best of luck!
Register for Wednesday's AJR Live Webinar with
@AndrewCallenMD
to learn about the first line appropriate imaging tests to order in a patient with suspected spontaneous intracranial hypotension.
A packed procedure day always puts me in a great mood! Great cases, hard working trainees, excellent staff, and lovely patients.
#SIH
@CUAnschutz
@CUMedicalSchool
"Remember the patient" is my favorite quote from one of my favorite teachers
@williamdillonmd
- not only in complicated spines but also in cases with lots of motion artifact, perhaps the most frustrating to read but often harbor pathology in the suffering patient.
Just had an ordering clinician ask if the brain MRI could be "dry" or if it should be with contrast... I paused but decided I like this term and will now use it and pretend I always have.
That’s a wrap! Thank you to all of our patient speakers, all of our provider speakers, all of our moderators, the University of Colorado Anschutz depts of neurology, neurosurgery, and neuroradiology, and our course director,
@AndrewCallenMD
!
"Hedging" in radiology can be frustrating to the clinicians reading our reports, but the expression of uncertainty is a necessary part of reporting. We examine which radiology subspecialties and which types of patients tend to have the most uncertainty:
Two things I am grateful for:
-
@JaredNarvid
and
@UCSFimaging
for developing my interest in CVR
-Our volunteers, many of whom suffer from long COVID and are not fully understood. Though different, I feel parallels to my
#SIH
patients. Maybe imaging can help provide an answer.
Dr. Callen's (
@AndrewCallenMD
) team assessed the association of prior
#COVID19
infection with cerebrovascular reactivity + vessel wall imaging abnormalities, and explored the association of CVR impairment with post-COVID neurologic conditions
#LongCovid
📑 NEW PAPER ALERT 📑
@NeuroradLal
@dgleao
@brainscandan
@Neuroshadow
“We describe an imaging sign on T2-weighted images caused by CSF-flow egress at the site of the defect that may permit accurate prediction of the site of the CSF leak non-invasively.”
#Coloradans
- have you or someone you know been infected with
#COVID19
, and had a blood clot, stroke, or heart attack? We are currently enrolling volunteers for an IRB approved MRI study evaluating the health of the blood vessels in your brain.
DM me for info!
@CUAnschutz
This was a fantastic lecture. Thank you to my alma mater for spotlighting
#SIH
and to Dr. Linda Gray
@LindaGr4510
for everything she has contributed to this field.
Important information about long term risks of living with a leak to cite to our
#SIH
#CSFLeak
patients who might have "mild" symptoms and be averse to definitive surgical intervention.
Spontaneous spinal CSF leaks are a common cause of superficial siderosis. Chronic bleeding into the subarachnoid space is the cause and it can be seen in most types of CSF leaks, but especially ventral leaks.
@spinalCSFleak
@LivingwithSS
Think twice before invoking a skull base dural AVF based on hyperintense ASL/TOF signal in the left sigmoid sinus- it might be jugular reflux!
@traviscaton
As gender-affirming facial feminization surgery is increasingly performed, so is preoperative planning CT. Radiologists have a key role in describing findings relevant to the surgical approach.
Check out our new article in AJR:
We use 4D-flow MRI cerebral vasoreactivity testing to illustrate the underlying pathophysiology of Moyamoya disease and reveal the intracranial flow changes that occur following surgical bypass:
@NeurosurgUCSF
@CURadiology
@UCSFimaging
@BrentWeinberg
The only thing more important than arguments over minor semantic distinctions are arguments about arguments about minor semantic distinctions.
Huge congrats to superstar
@CUMedicalSchool
student
@RyanATurner
for taking the lead on the case and publishing his first- first author paper! An excellent neuroradiologist in the making!
@PeterGKranz
On all the ones I have seen, you could make the call on the MRI, and with increased confidence if you have 3DT2FS acquisition. Sometimes the finding is so tiny however that it is more convincing in retrospect once you see it fill with contrast.