Adam Hendricks
@Adam91726300
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motor proteins, intracellular transport, cytoskeleton
Montréal, QC
Joined January 2014
RT @CellReports: Optogenetic control of kinesin-1, -2, -3 and dynein reveals their specific roles in vesicular transport
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RT @DumontLab: Nominate a colleague or yourself to speak at the Motility & Cytoskeleton Subgroup at the 2025 Biophysical Society Meeting! R…
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New paper from the lab! Daniel Beaudet shows that early phagosomes are transported by heterogeneous sets of kinesin-1, kinesin-3, and dynein motors resulting in long, directed runs.
New in JBC press: "Scientists isolated endocytic organelles from cells at different stages of maturation and reconstituted their motility along microtubules in vitro." Learn more:
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RT @CRBSMcGill: Branches, McGill's Community Outreach Program, spent a week with the Cree nation in Chisasibi (QC) to deliver workshops, in…
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Congrats to Emily Prowse and Brooke Turkalj for leading the study, with help from Muriel Sébastien and Daniel Beaudet and collaborators @pouladilab, Gary Brouhard, and @mitodynamics!
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RT @CIHR_IRSC: Attention all those applying to the Project Grant competition! We were not as clear as we could have been regarding new req…
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RT @biorxiv_cellbio: Doublecortin regulates neuronal migration by editing the tubulin code #biorxiv_cellbio
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@ManuelTHERY @DrFlorianBerger We used Zdk1, which localizes back to the LOV2-mito in ~10 s after the blue light is removed. However, the Hahn lab developed other versions of Zdk that would remain cytosolic for longer periods (see Wang et al., 2016, Nat. Methods)
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@ManuelTHERY @DrFlorianBerger Yes - one of the advantages of this approach is that allows us to test the function of the endogenous motors. Only the optogenetic inhibitors are over expressed.
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We hypothesize each motor has a specific role. Kinesin-1 and dynein control the direction of movement, while kinesin-2 and -3 assist in long-range transport.
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New work from undergraduate extraordinaire Ora shows that two dominant timescales of cytoskeletal crosslinking govern the cell's viscoelastic response.
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The published version contains lots of new results since we posted the preprint! Congrats to the team and thanks for all your hard work!
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