RT @SenSchumer: Welcome to the age of Trumpflation. Groceries are up. Chicken, pork, steak are all more expensive. Eggs prices are up 15%…

@George_E_Naoum @IJROBP @ASTRO_org @ARRO_org @QuadShotNews Interesting work. Reminds me of:

@radiopeppe R&O too 😝

EXCLAIM-2: Mobocertinib vs Chemo in EGFR Exon 20 Insertion–Positive Metastatic Non–Small Cell Lung Cancer Mobocertinib is literally targeted for exon 20 insertion in EGFR Yet: PFS HR 1.04 (0.77-1.39) A great example of “precision medicine” failure

Type I error rate is not a rate and is not the probability of an error. It is the probability of making an assertion of an effect when *any* such assertion is by definition wrong (emphasis mine) HT @f2harrell Ch 22 #bbr

Testing the treatment effect in a molecular subgroup does not carry along with it the covariate adjustment needed here; this is grossly misleading! This work is a good example of being so focused on “sexy” molecular biomarkers, baseline clinical variables are ignored here

@GregAbbott_TX Oh boy, you really showed them

Typo: “randomize.” -> “randomized trial”

@EvanThomas84 @VPrasadMDMPH

@RWJE_BA Yes exactly, saying “retrospective observational” or “prospective observational” doesn’t get as many papers that shouldn’t be accepted as accepted as does “emulated randomized” or “pseudo randomized”. Total BS

@RWJE_BA @AdanBecerraPhD Yes. We care about relative treatment effectiveness over some relevant time horizon. @f2harrell gets it perfect here

@RWJE_BA @AdanBecerraPhD But then we wouldn’t get talks like this on how without causal inference AI is “fake intelligence” 😂

@imsmart420 @SuyogCancer @OncBrothers @tuttsakhil @Erman_Akkus @ErikaHamilton9 @todrashish I think important to consider less side effects and less costs with less

RT @TheRickWilson: Gas prices, up. Grocery prices, up. Egg prices, up. Inflation, up.

@RWJE_BA @AdanBecerraPhD Yes we must achieve true precision medicine with waterfall plots, biomarkers, and causal AI 🤪

Wtf am I looking at here? What a circus 🎪