JAMA
@JAMA_current
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JAMA is an international peer-reviewed general medical journal published weekly online and in print, and a member of the @JAMANetwork family of journals.
Chicago, IL
Joined May 2009
This JAMA Clinical Guidelines Synopsis summarizes the 2024 Society of Critical Care Medicine guidelines on use of corticosteroids in sepsis, acute respiratory distress syndrome, and community-acquired pneumonia.
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An Open Letter From @jamanetwork's Editor."The undermining of science - and unprecedented attacks on scientists and public health officials - risks lives in every corner of our country".@WhiteHouse @realDonaldTrump @POTUS @Mike_Pence .@NIAIDNews @NIHDirector @CDCgov @CDCDirector
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Plantar fasciitis is a common cause of heel pain among adults. This JAMA Patient Page describes the condition of plantar fasciitis and its diagnosis and treatment.
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"The Pfizer/BioNTech vaccine prevents clinical disease but it it still unclear if it prevents asymptomatic infection, or asymptomatic transmission." Anthony Fauci, MD.Complete interview at #COVID19 #Coronavirus #Fauci #covidvaccine
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Among outpatient health care personnel, N95 respirator masks did not reduce incidence of laboratory-confirmed influenza vs standard medical face masks
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Review summarizes current evidence regarding the epidemiology, pathophysiology, diagnosis, treatment, and prevention of diabetic foot ulcers.
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Diabetic foot ulcers are wounds on the feet that develop in patients with type 1 or type 2 diabetes. This JAMA Patient Page describes diabetic foot ulcers and their evaluation and treatment.
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Plantar fasciitis is a common cause of heel pain among adults. This JAMA Patient Page describes the condition of plantar fasciitis and its diagnosis and treatment.
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A recent systematic review of studies suggests that medical students in countries around the world haven’t been getting the education they need to counsel patients on healthy eating
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"This is a race we want everyone to win. If Russia, China have an effective vaccine maybe they can take care of themselves, even other countries. Success anywhere helps everyone & is a step toward global protection" .#CovidVaccine #COVID19 #SputnikV #fauci
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In a study of unvaccinated US adults up to 20 months, antibodies were detected in 99% of people who reported a positive COVID-19 test result, in 55% who believed they had COVID-19 but were never tested, and in 11% who believed they had never had #COVID19.
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Very low-carbohydrate, high-fat #KetogenicDiets cause the body to switch from burning carbs to burning fat. A meta-analysis of 13 RCTs suggested that people on ketogenic diets tend to lose more weight and keep more of it off than people on low-fat diets.
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Among hospitalized adults, the risk of acute kidney injury did not differ between cefepime and piperacillin-tazobactam, but neurological dysfunction was more common with cefepime. #IDWeek2023
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Narrative review explores how to manage use of DOACs—apixaban, rivaroxaban, edoxaban, and dabigatran—in patients undergoing surgical and nonsurgical procedures to decrease risks of bleeding and thromboembolism.
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🧵 Just published: USPSTF recommends all women undergo routine #breastcancer screening every other year beginning at age 40, an update from the 2016 recommendation to start at age 50.
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Masks should not be worn by healthy people to prevent respiratory infection; there is no evidence that wearing masks prevents healthy people from getting sick and masks can be in short supply and unavailable for people who need them
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The rising tide of medical misinformation requires a robust and coordinated response from health professionals, organizations, institutions, and mainstream media
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The Chinese CDC today published the largest case series to date of #COVID19 in mainland China (72 314 cases through 2/11/20). Here are some of the data:.Case-fatality rate .• 2.3% Overall.• 14.8% age >= 80 .• 8.0% age 70-79.• 49.0% in critical cases.
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Syncope or near-syncope is the most common reason physicians are called to attend to in-flight medical emergencies. Learn more:
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"It’s all in your head” is a phrase sometimes said by physicians to patients presenting w symptoms unexplained by medical disease. As a neurologist specializing in neuropsychiatry I find myself constantly trying to repair the damage these words can cause.
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The prevalence of adolescent obesity is approximately 21% in the US. This Review summarizes the current evidence regarding the epidemiology, pathophysiology, diagnosis, and treatment in adolescents, with a focus on management of obesity.
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Medschool students should be taught communication, ethics, stats, financing, law, management
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The decision to undergo surgery for older adults should include considerations of how much the procedure will improve quantity and quality of life, and how much it will preserve their independence.
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Why is it acceptable care if P.T. doesn’t come every day but unacceptable if antibiotics aren't given daily? Or acceptable to miss meals waiting for procedures that are cancelled? Why do alarms go off in patients' rooms to notify nurses who are elsewhere?
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Acetaminophen use during pregnancy was not associated with children’s risk of autism, ADHD, or intellectual disability in sibling control analysis.
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.@PLOSMedicine reports taking #melatonin about an hour before turning in for the night improved sleep disturbances and sleep-related impairments in patients who had trouble falling asleep at their chosen bedtime and difficulty waking the next day
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"Tony Fauci has one goal - to restore America to some semblance of health so that it can once again be a functioning society. He deserves our deepest gratitude and support." .July 14 Open Letter from @jamanetwork's Editor-in-Chief.
An Open Letter From @jamanetwork's Editor."The undermining of science - and unprecedented attacks on scientists and public health officials - risks lives in every corner of our country".@WhiteHouse @realDonaldTrump @POTUS @Mike_Pence .@NIAIDNews @NIHDirector @CDCgov @CDCDirector
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#Coronavirus in Italy: @DrMCecconi, @ESICM president-elect and ICU physician in Lombardy has helped develop a #COVID19 ICU Network to manage the surge of critical care patients. He discusses his experiences and lessons learned with Howard Bauchner.
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Atrial fibrillation (AF) is associated with increased rates of stroke, heart failure, and mortality. This narrative review examines the epidemiology, pathophysiology, diagnosis, and treatment of AF.
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"I don't understand how we protect the vulnerable in society and somehow get to herd immunity through an infection pathway. I think that is just going to lead to a lot of death" @RWalensky .@MartinKulldorff @SunetraGupta.#GreatBarringtonDeclaration #JohnSnowMemorandum
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Sodium reduction significantly lowered blood pressure in the majority of middle-aged to elderly adults in this study.
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Prediabetes is a condition in which blood glucose levels are high but lower than in type 2 diabetes. This JAMA Patient Page describes prediabetes and its symptoms, diagnosis, and management strategies.
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Marfan syndrome is a disorder that affects connective tissue throughout the body. This JAMA Patient Page discusses the diagnosis and treatment of #MarfanSyndrome.
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Falls are the leading cause of injury in adults aged 65 years or older. This JAMA Patient Page describes risk of falls in older adults and fall prevention recommendations from the US Preventive Services Task Force.
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Although #measles #vaccination has saved more than 21 million lives since 2000, reported measles cases increased worldwide by 31% from 2016 to 2017 in large part because of falling vaccination coverage, according to a recent report
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Medschool students should be taught communication, ethics, stats, financing, law, management
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Among adults in the ICU who had sepsis or septic shock, the use of prolonged β-lactam antibiotic infusions was associated with a reduced risk of 90-day mortality compared with intermittent infusions, finds meta-analysis. . #CCR24
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Acute pericarditis is a common cause of nonischemic chest pain. This Review article examines the causes, treatments, and prognosis of both acute and recurrent pericarditis.
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The primary benefit of wearing a mask is in limiting the spread of #COVID19 from others who are symptomatic or asymptomatic. Masks also remind others to continue practicing #physicaldistancing
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In both my life and my clinical career I am awed by the therapeutic value of silence. When there are no words, I sit quietly with patients and and their families, allowing time and space for their stories to unfold. #medhum.
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Despite widespread availability and use of calcium and vitamin D to prevent osteoporotic fractures, this meta-analysis of 33 clinical trials found no effect of the supplements' use on hip, other nonvertebral, vertebral, or total fractures.
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The risk of contracting #COVID19 during air travel is lower than from an office building, classroom, or supermarket. Airplanes circulate a mix of fresh air and air recycled through HEPA filters. Wear a mask and don’t travel if you feel unwell
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A 3-year experiment in providing housing to frequent emergency department patients at @UIHealth has been so successful that in 2018, the hospital decided to double the housing program’s size
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Older women who walked more than their peers had lower death rates in a recent observational study in @JAMAInternalMed, and the mortality benefit was seen with as few as 4400 steps
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In this preliminary uncontrolled case series of 5 critically ill patients with #COVID19 and #ARDS, administration of convalescent plasma containing neutralizing antibody was followed by improvement in the patients’ clinical status #Coronavirus.
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SARS-CoV-2 uses the SARS-COV receptor angiotensin converting enzyme (ACE) 2 for entry into target cells, raising the hypothesis that ACE-inhibitor/angiotensin-receptor blockade could increase expression of ACE2 receptor in virus-targeted cells and lead to worse outcomes.
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Study found no #SARSCoV2 infections among community health workers after the addition of face shields to their personal protective equipment
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Maintenance dialysis for chronic kidney failure is associated with high mortality and frequent complications. This Review summarizes the pathophysiology, diagnosis, and management of dialysis-dependent chronic kidney failure.
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Diabetic foot ulcers are wounds on the feet that develop in patients with type 1 or type 2 diabetes. This JAMA Patient Page describes diabetic foot ulcers and their evaluation and treatment.
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Exercise preconditioning triggers adaptive responses of the heart and coronary arteries that protect against ischemia and infarction. This narrative evidence review concludes that even short exercise can create clinically relevant cardioprotection.
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Canker sores are small, painful ulcers that develop inside the mouth. This JAMA Patient Page describes the types of canker sores and how they can be treated.
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Review summarizes current evidence regarding the diagnosis and treatment of depression in adults.
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Today, the FDA approved two sickle cell treatments, including one that uses gene therapy. For more on sickle cell disease, read this 2022 JAMA review article.
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Only 2 types of doctors never have surgical complications: those who don’t operate and those who aren’t truthful.
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Obesity is associated with multiple comorbidities. This review examines the safety and efficacy of antiobesity medications in conjunction with lifestyle modification according to their mechanism of action.
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5 practices may enhance physician presence and connection w patients in clinical encounters: .(1) Prepare w intention; .(2) Listen intently & completely; .(3) Agree on what matters most; .(4) Connect w the patient’s story; .(5) Explore emotional cues.
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Read one of our most cited articles of 2021, “Diagnosis and Treatment of Multiple Sclerosis | A Review,” which discusses the epidemiology and pathophysiology of MS and summarizes evidence on its diagnosis and treatment.
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The decision to undergo surgery for older adults should include considerations of how much the procedure will improve quantity and quality of life, and how much it will preserve their independence.
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Canker sores are small, painful ulcers that develop inside the mouth. This JAMA Patient Page describes the types of canker sores and how they can be treated.
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The American Heart Association’s new cardiovascular disease risk calculator, PREVENT, is set to be released in January. Here's how it improves on the decade-old pooled cohort equations. #MedicalNews .
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How to interpret 2 types of diagnostic tests commonly in use for #SARSCoV2 infections—RT-PCR and IgM and IgG enzyme-linked immunosorbent assay (ELISA)—and how the results may vary over time #COVID19 #Coronavirus.
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Declines in SARSCoV2 IgG neutralizing Abs raise concerns of susceptibility to reinfection. But acute Ab levels always decline post-infection, and Ab recall responses come from a pool of long-lived memory B cells
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Review summarizes current evidence regarding the diagnosis and treatment of interstitial lung disease.
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Less medicine is better medicine. Physical exam maneuvers are more performative than informative. Physicians complete suicide. These modern concepts are documented in a novel that recently celebrated its 40th anniversary, Samuel Shem’s The House of God.
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JAMA Clinical Guidelines Synopsis summarizes the 2023 @ACCinTouch @American_Heart @ACCP @HRSonline guideline for the diagnosis and management of atrial fibrillation.
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In this small crossover study, wearing a 3-layer nonmedical mask was not associated with a decline in oxygen saturation in older adults. The results refute claims that wearing masks in community settings is unsafe for #COVID19 mitigation @McMasterU.
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This Review on community-acquired pneumonia summarizes current evidence on pathogenesis, epidemiology, diagnosis, and treatment, with a focus on adults without immune-compromising conditions.
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This article summarizes the recent update of guidelines on health care for transgender and gender diverse people, including primary care, gender-affirming care, mental health care, and education of the clinical workforce.
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🧵 New Special Communication examines drawing causal inferences about the effects of interventions from observational studies in medical journals and suggests a framework that might be used.
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Cervical cancer mortality in US women younger than 25 years significantly declined between 2016 and 2021, likely due to the widespread adoption of HPV vaccination.
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Congratulations to JAMA Medical Illustrator Nick Reback on being recognized with an @amidotorg Award of Merit for his illustration “Will This Patient Be Difficult to Intubate?” Check out the awesome work that won him the award at ! @IDrawPicsAllDay
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Emerging evidence suggests that optimal lipid lowering therapy produces the greatest absolute reduction in apoB. Because 90% of circulating apoB particles are LDL, therapy that reduces LDL-C (eg #statins) are optimal first therapy for most people
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Enough is known about the health effects of #loneliness that physicians need to be able to recognize it
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The US continued to experience significantly higher #COVID19 and excess all-cause mortality compared with peer countries during 2021 and early 2022, a difference accounting for 150 000-470 000 deaths.
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A man in his 40s given pembrolizumab for malignant melanoma developed diffuse darkening of his skin, nail beds, and sclera after starting treatment; the image shows him holding a recent driver’s license photo. What is the cause of the change?
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Narrative review explores how to manage use of DOACs—apixaban, rivaroxaban, edoxaban, and dabigatran—in patients undergoing surgical and nonsurgical procedures to decrease risks of bleeding and thromboembolism.
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Physicians are stressed by this pandemic—by the fear of being infected by a contagious and deadly virus, by the fear of infecting our own loved ones, by the constant reminder of our own mortality. We are not immune just because we are doctors
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The FDA approved use of the SGLT2 inhibitor dapagliflozin for treatment of HFrEF irrespective of diabetes status, and it's expected to become guideline-directed medical therapy for all patients with HFrEF in the 2021 ACC/AHA #heartfailure guideline
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Viewpoint: Medical students and residents need to be educated on health policy issues like insurance, payment models, and drug regulation to better understand the factors that impact patient health outcomes.
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Ceasing involuntary displacement of people experiencing homelessness may mitigate some health-related harms associated with #homelessness.
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“Seize diastole,” my med school professor said. The words were a clever metaphor for living life well. Diastole isn't passive. It takes work to relax. to give oneself permission to feel, to let one's heart expand fully. Thank you @colleenfarrell
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Narrative review summarizes current evidence regarding the diagnosis and management of cirrhosis and its complications. Article discussed during a top JAMA 2023 Clinical Reviews podcast.
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Study found robust secretion of #SARSCoV2 specific IgA and IgG antibodies in breast milk for 6 weeks after maternal vaccination, suggesting a potential protective effect against infection in the infant.
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“Digital addiction” represents a real and potential widespread problem that defies easy solutions or prevention strategies. Time spent on a device or activity is not as important as how that time is spent that matters.
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