Cell
@CellCellPress
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Cell aims to publish the most exciting and provocative research in biology. Posts by Scientific Editors on the Cell Editorial team.
Cambridge, MA
Joined August 2009
The new issue is out!! 👉 Featuring the engineering of source-sink relations to.create climate-smart crops, how ongoing chromothripsis drives tumor evolution across sarcomas and carcinomas, and the intercellular propagation of pyroptosis! . 📷: Jake
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In the latest issue! The primitive endoderm supports lineage plasticity to enable regulative development
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In the latest issue! “Boosting” tumor immunity in elderly mice by hyperactivating dendritic cells
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In the latest issue! Systematic mapping of organism-scale gene-regulatory networks in aging using population asynchrony
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In the latest issue! TERT activation targets DNA methylation and multiple aging hallmarks
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In the latest issue! Amplification editing enables efficient and precise duplication of DNA from short sequence to megabase and chromosomal scale
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In the latest issue! Open-ST: High-resolution spatial transcriptomics in 3D
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Now online! Discovery of deaminase functions by structure-based protein clustering
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Revisit our recent anniversary focus issue on #Metabolism for exciting content on metabolism and its connections to disease and aging. Explore the issue: #50YearsofCell
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Now online! Neutrophil trapping and nexocytosis, mast cell-mediated processes for inflammatory signal relay
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Now online! The fork protection complex promotes parental histone recycling and epigenetic memory
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Now online! Allogeneic CD19-targeted CAR-T therapy in patients with severe myositis and systemic sclerosis
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A #SARSCoV2 variant carrying the #Spike #protein amino acid change #D614G is potentially associated with greater #infectivity and higher #viral loads. Online now! For all @CellPressNews #coronavirus research, visit #COVID19
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In the latest issue! The extracellular matrix integrates mitochondrial homeostasis
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Today Cell, Cancer Cell and Cell Reports Medicine are pleased to publish the 1st wave of Pan-#Cancer multiomics papers looking at over 1000 patients across 10 #tumor types from @theNCI Clinical Proteomic Tumor Analysis Consortium #CPTAC (1/n) @Cancer_Cell @CellRepMed #openaccess
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We are horrified and angered by the brutality repeatedly faced by Black Americans, and we stand in solidarity with those protesting violence against Black Americans and the systemic racism and discrimination that feed it. Black lives matter. #BlackLivesMatter.
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Out now! A #comprehensive multi-omics analysis from 59 #astronauts provides insight into important #biological mechanisms affected by #spaceflight. @NASA @AfshinBeheshti ☄️🛰️🚀
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Online now! RNA promotes the formation of spatial compartments in the nucleus.#sciencetwitter #RNA.
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In the latest issue! Microglial-derived C1q integrates into neuronal ribonucleoprotein complexes and impacts protein homeostasis in the aging brain
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Genetically modified silkworms successfully produce spider silk.; a natural fiber six times tougher than Kevlar. Read more in @Matter_CP: #SouthwestUniversty Qingyou Xia.#DonghuaUniversity Qing Meng
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The new issue is out! Just in time for #WorldAlzheimersMonth, Cell features four articles that together demonstrate the genomic, epigenomic, and transcriptomic dysregulations underpinning Alzheimer's disease at single-cell resolution across cell types. To read more click
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In the latest issue! Integrated cryoEM structure of a spumaretrovirus reveals cross-kingdom evolutionary relationships and the molecular basis for assembly and virus entry
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Our Juneteenth-themed issue is out! It features several articles highlighting the voices, perspectives and stories of over 70 outstanding Black scientists! . On the cover, Mays et al. describe the historical context of the Juneteenth holiday in the
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In the latest issue! A metabolic balance of GLP-1 and NMDA receptors in the brain
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Out now! #Cancer cells can enter a quiescent state in response to #chemotherapy and subsequently emerge rejuvenated @UHN @UHN_Research
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Online now! Stereo-seq combines DNA nanoball patterned arrays and tissue RNA capture to achieve large field-of-view spatial transcriptomics at cellular resolution!.#sciencetwitter #singlecell .
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A new technique, #TrimAway, directly degrades endogenous proteins in mammalian cells within minutes of application (without a need for prior modification of the genome or mRNA)! Free article -->
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In the latest issue! Migrating cells selectively remove damaged mitochondria to maintain homeostasis in a process called mitocytosis.@Tsinghua_Uni.
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Online now! #Clinical trial #data suggests that BCG #vaccination is safe and can #protect the #elderly against #infections
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The new issue is out! Featuring a chimeric monkey composed of embryonic stem cells, the mechanopathology of tuberculosis infection, and the development of NMDAR-CAAR T cells that precisely target pathogenic B cells in encephalitis.. To browse our new issue click
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New Resource online now! A single-cell atlas of chromatin accessibility in the human genome 🧬🧬.#sciencetwitter #chromatin #singlecell .
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Now online! Neuronal ensembles in the mouse insular cortex that are activated during distinct inflammatory conditions, are capable of modulating peripheral immunological responses.#neuroscience .
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Now online! An antibiotic from an uncultured bacterium binds to an immutable target
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Now online! Activation of the helper NRC4 immune receptor forms a hexameric resistosome
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SHARE-seq is a highly #scalable approach to measure both #chromatin accessibility and #gene #expression in the same #cell. New Resource online now!
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In the latest issue! Preclinical proof of principle for orally delivered Th17 antagonist miniproteins
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Now online! Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2
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Online now! This gene expression map in mature C. elegans captures all 302 neurons and deciphers the molecular basis for cell heterogeneity, connectivity, and function.#neuroscience.
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Our new issue is out! Featuring synthetic mammalian cellular signaling circuits, local hyperthermia therapy to treat obesity, and a reconstruction of mouse visual cortex!.#newissue #sciencetwitter
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An entire fly brain in electron microscopy, at the resolution of individual synapses: @dddavi &co @HHMIJanelia 's work is online and 🔓.Explore the data further here:
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How can we measure the #memory of a single #cell? MemorySeq can reveal new forms of #biological memory by identifying slowly fluctuating #gene expression states in rare single #cells. Online now!
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Now online! Molecular mechanism of distinct chemokine engagement and functional divergence of the human Duffy antigen receptor
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Bringing 2023 to a close, the new issue features a 3D atlas of the developing human head, how the ineffective control of EBV-induced autoimmunity increases the risk for multiple sclerosis and a machine learning architecture that integrates cell types across single-cell datasets!
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Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins @davidrliu
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Two new studies on #Omicron tell us how individuals vaccinated 3x with mRNA vaccines or those with mixed vaccination may be better protected. What does this mean for the #COVID19 pandemic? Read more: @BalazsLab @snpoehlm #SARSCoV2
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New Article now online: Lymph nodes are innervated by a unique population of sensory neurons with immunomodulatory potential
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Online Now: Structures of human #antibodies derived from recovered individuals that are bound to the #SARSCoV2 spike reveal common epitopes and recurrent features @cobarnes27 @bjorkmanlab @NussenzweigL #COVID19
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#ACE2 expression is stimulated by IFN-α in human epithelial cells suggesting #SARSCoV2 can exploit lung tissue protective mechanisms for cellular entry Now @cellcellpress.@CellPressNews #coronavirus research, visit #COVID19
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The new issue is out! Featuring the deep population history of northern East Asia, cardioids that recapitulate chamber-like structures, and RNAs modified with N-glycans!.#NewIssue.
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Online now! A #natural single-guide #RNA that directs Cas9 to #transcriptionally repress its own #promoter
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Out now! A single-cell atlas of gene expression and chromatin accessibility of the human developing cortex during mid-gestation identifies prioritized mutations for Autism Spectrum Disorder.#neuroscience #developmentalbiology.@PascaStanford @Stanford.
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Now online! RNA polymerase II dynamics and mRNA stability feedback scale mRNA amounts with cell size
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In the latest issue! Advancing natural killer therapies against cancer
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As part of the #50YearsofCell, our focus issue on Immunology is out! ..This issue brings Cell’s 50th anniversary celebrations straight to your lymph nodes with reviews, perspectives and more thought-provoking articles on topics ranging from innate immunity to plant immune
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Now online! Neurodegeneration in Parkinson’s disease occurs via PAAN/MIF nuclease activity. Inhibition of this nuclease with a small molecule inhibitor prevents this neurodegeneration!.#sciencetwitter #neuroscience 🧠🧠.
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For the 2nd week, the Cell editorial recommended reads from our #cancer Special Issue start with a Review on #macrophages in #cancer and how these contribute to #tumor evolution @LeilaAkkari1 @djkloosterman �(1/4).
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Cell stands with our Black readers, reviewers, authors, and colleagues, against racism and police brutality. We are committed to amplifying their voices, to educating ourselves, and to finding ways that we can do better. #BlackLivesMatter. Our editorial:
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Online now! Multiplexed FISH in thick tissue sections, with deep-learning based 3D segmentation, enables characterization of the spatial organization for different cell types in defined brain regions.#sciencetwitter 🧠🧠.
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As part of the #50YearsofCell, our focus issue on Genomics and Genetics is out! . From drug discovery to human evolution, conservation to gene editing, we are excited to showcase the vibrancy of the science, the methodology, and the people of genetics
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We are sad to learn of Dr. Angelika Amon's passing. We wish her family, members of her lab and those close to her strength during this difficult time. Her remarkable legacy, advocacy for women in science and guidance as an advisory board member for the journal were invaluable.
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In the latest issue! 100 years of the Warburg effect: A cancer metabolism endeavor
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Online now! A multiomics study in humans investigating the longitudinal effects of a high-fiber or fermented-food diet shows their effects on the diversity of the microbiome.#microbiology #microbiome 🦠🦠🍞🍇🧀🦠🦠.
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In the latest issue! Spatial proteomics in neurons at single-protein resolution
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Now online! Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals
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Now online! Direct observation of a condensate effect on super-enhancer controlled gene bursting
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Check out our new primer on #MachineLearning for #biologists including a foray into deep learning @wyssinstitute @broadinstitute @MITdeptofBE @CUAnschutz @MIT
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As part of the #50YearsofCell, our focus issue on Cancer is out! .. In this issue, you'll find reviews, perspectives, and BenchMarks on the systemic complexity of cancer, and on some of the genes and proteins most intricately involved in the
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Now online! Distinct longevity mechanisms across and within species and their association with aging
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Now online! Small RNAs are modified with N-glycans and displayed on the surface of living cells
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Cell is turning 50! Come join us as we celebrate half a century of excellent biology with themed issues all year long. To learn more, read the editorial from our team: . Cover art by Julie Sung:
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In the latest issue! High-fat #diets impair #T-cell function in the #tumor microenvironment accelerating tumor growth @HaigisLab @harvardmed
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Online now! Generation of the C3a complement protein fragment by #SARSCoV2 infection drives differentiation of a CD16-expressing T cell population that associates with severe #COVID19 disease outcomes.For all @CellPressNews #coronavirus research visit
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Just brilliant! 🤩.
@Elinav_Lab @CellCellPress I used @p5xjs to make this very nice journal cover playable. Try it here:
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New Editorial online now at Cell: Science Has a Racism Problem
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Now out! Stereo-seq combines DNA nanoball patterned arrays and tissue RNA capture to achieve large field-of-view spatial transcriptomics at cellular resolution!.#sciencetwitter.
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Now live: A special, interdisciplinary focus issue on Sex and Gender in science from Cell!!. The issue explores the evolution of science’s approach to understanding sex and gender—and how more accurate, precise, and inclusive approaches can lead to
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Now online! Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth
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New Review online now! This review #explores the #molecular and #cellular aspects of #lung aging and how the #aging process predisposes to the #pathogenesis of pulmonary #disease
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The new issue is out! Featuring the temporal dynamics of woolly mammoth genome erosion prior to extinction, and the three-dimensional genome architecture from a 52,000 year old woolly mammoth skin sample!.🦣🦣.To read more from our new issue, click here
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New Resource online now at Cell: A Quantitative Proteome Map of the Human Body
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Now online! The host immune system uses the endogenous virome to communicate with the exogenous microbiota in a multikingdom interaction that modulates tissue repair and inflammation. #microbiome #virome🦠🦠🦠.
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A subset of sensory #neurons are involved in an unexpected #neuroimmune mechanism that maintains cutaneous #immune homeostasis. Now online!
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We are pleased to bring you the @CellCellPress paper of #FacesOfCell Dr. Neftaly Cruz Mireles (@NeftalyCM), “The phosphorylation landscape of infection-related development by the rice blast fungus”.
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Now online! Commensal #microbiota regulate #interferon signaling to #protect against #pathogenic #viral #infections.
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In the latest issue! Cell surface RNAs control neutrophil recruitment
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New Review online now at Cell: The Self-Organizing Genome: Principles of Genome Architecture and Function
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In the latest issue! Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation
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Now online! A single transcription factor is able to regulate caste identity in ants by acting as a core transcriptional regulator in response to caste-specific hormone signaling.#ants #sciencetwitter 🐜🐜.
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In the latest issue! Cytotoxic CD4+ T cells eliminate senescent cells by targeting cytomegalovirus antigen
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