
soft/living matter fanclub
@softlivmat_fc
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we highlight the latest articles that bring together physics and biology.
Joined August 2020
soft/living matter fanclub is now also available on bluesky!
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L. Balasubramaniam, et al., Dynamic forces shape the survival fate of eliminated cells. Nat. Phys. 1–10 (2025).
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F. L. Lampart, et al., Morphometry and mechanical instability at the onset of epithelial bladder cancer. Nat. Phys. 1–10 (2025).
nature.com
Nature Physics - Carcinoma subtypes are normally linked to specific genetic alterations, but tissue mechanical changes also play a role. Now, aberrant morphologies resembling bladder carcinoma are...
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G. Šneiderienė, et al., Lipid-induced condensate formation from the Alzheimer’s Aβ peptide triggers amyloid aggregation. Proc. Natl. Acad. Sci. U. S. A. 122, e2401307122 (2025).
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T. Tlusty, A. Libchaber, Life sets off a cascade of machines. Proc. Natl. Acad. Sci. U. S. A. 122, e2418000122 (2025).
pnas.org
Life is invasive, occupying all physically accessible scales, stretching between almost nothing (protons, electrons, and photons) and almost everyt...
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A. A. Fragkopoulos, F. Böhme, N. Drewes, O. Bäumchen, Metabolic activity controls the emergence of coherent flows in microbial suspensions. Proc. Natl. Acad. Sci. U. S. A. 122, e2413340122 (2025).
pnas.org
Photosynthetic microbes have evolved and successfully adapted to the ever-changing environmental conditions in complex microhabitats throughout alm...
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J. Wang, J. E. Butler, A. J. C. Ladd, Microfluidic purification of genomic DNA. Proc. Natl. Acad. Sci. U. S. A. 122, e2417757122 (2025).
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D. Valverde-Mendez, et al., Macromolecular interactions and geometrical confinement determine the 3D diffusion of ribosome-sized particles in live Escherichia coli cells. Proc. Natl. Acad. Sci. U. S. A. 122, e2406340121 (2025).
pnas.org
The crowded bacterial cytoplasm is composed of biomolecules that span several orders of magnitude in size and electrical charge. This complexity ha...
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H. J. Oh, et al., Size-controlled assembly of phase separated protein condensates with interfacial protein cages. Nat. Commun. 16, 1–14 (2025).
nature.com
Nature Communications - This study introduces a one-pot method to create and control protein condensates using surface-stabilizing protein cages, allowing size tuning from the micro- to nanoscale...
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K. Tomohara, Y. Minagawa, H. Noji, Artificial cells with all-aqueous droplet-in-droplet structures for spatially separated transcription and translation. Nat. Commun. 16, 1–11 (2025).
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E. Han, et al., Local polar order controls mechanical stress and triggers layer formation in Myxococcus xanthus colonies. Nat. Commun. 16, 952 (2025).
nature.com
Nature Communications - The decision to form a fruiting body have been studied extensively, however, the mechanical events that trigger the creation of multiple cell layers is poorly understood....
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M. Burman, A. Noy, Atomic description of the reciprocal action between supercoils and melting bubbles on linear DNA. Phys. Rev. Lett. 134 (2025).
journals.aps.org
Although the mechanical response of DNA to physiological torsion and tension is well characterized, the detailed structures are not yet known. By using molecular dynamics simulations on linear DNA...
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J. Liang, et al., Glass transition in monolayers of rough colloidal ellipsoids. Phys. Rev. Lett. 134 (2025).
journals.aps.org
Roughing up the surfaces of particles in a colloidal system can smooth its transition into a glassy state.
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W. D. Piñeros, É. Fodor, Biased ensembles of pulsating active matter. Phys. Rev. Lett. 134 (2025).
journals.aps.org
Ensembles of particles that actively pulsate in size which are also biased to select certain rare configurations can exhibit complex emergent behaviors that depend on system geometry.
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L. A. Hoffmann, L. Giomi, Homochirality in the Vicsek model: Fluctuations and potential implications for cellular flocks. Phys. Rev. E. 111 (2025).
journals.aps.org
Chirality is a feature of many biological systems, and much research has been focused on understanding the origin and implications of this property. Famously, sugars and amino acids found in nature...
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P. A. Haas, S. S. M. H. Höhn, Cut it out: Out-of-plane stresses in cell sheet folding of Volvox embryos. Phys. Rev. E. 111 (2025).
journals.aps.org
This work analyzes the mechanical dynamics driving inversion of the $V\phantom{\rule{0}{0ex}}o\phantom{\rule{0}{0ex}}l\phantom{\rule{0}{0ex}}v\phantom{\rule{0}{0ex}}o\phantom{\rule{0}{0ex}}x$ embryo,...
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S. R. Noureen, R. L. Mort, C. A. Yates, Modeling adhesion in stochastic and mean-field models of cell migration. Phys. Rev. E. 111 (2025).
journals.aps.org
Adhesion between cells plays an important role in many biological processes such as tissue morphogenesis and homeostasis, wound healing, and cancer cell metastasis. From a mathematical perspective,...
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A. Despons, Nonequilibrium properties of autocatalytic networks. Phys. Rev. E. 111 (2025).
journals.aps.org
Autocatalytic networks regulate the capability of a chemical system to produce copies of itself and are key for the metabolism of living systems. In this study, the author explores the relationship...
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H. Noguchi, Spatiotemporal pattern formation of membranes induced by surface molecular binding/unbinding. Soft Matter (2025).
pubs.rsc.org
Nonequilibrium membrane pattern formation is studied using meshless membrane simulation. We consider that molecules bind to either surface of a bilayer membrane and move to the opposite leaflet by...
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M. Safdari, S. Li, S. Panahandeh, P. van der Schoot, R. Zandi, Impact of the RNA binding domain localization of the protein shell on virus particle stability. arXiv [physics.bio-ph] (2025).
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C. Hanauer, et al., A model for self-organized growth, branching, and allometric scaling of the planarian gut. arXiv [physics.bio-ph] (2025).
arxiv.org
The growth and scaling of organs is a fundamental aspect of animal development. However, how organs grow to the right size and shape required by physiological demands, remains largely unknown....
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