Seb
@ibdseb
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IBD clinician& researcher @IBDHull . Elected councillor @BritSocGastro . Governing Board :ECCO NIHRresearch lead (Y&H)own views, RT🚫endorse.⚽️ @LFC fan.
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8
56
Delighted to see 🇬🇧 PANTS study 3 year extension data published in
@LancetGastroHep
🙏🏼 to the investigators and patients who participated
⏺️Only 1/3 of those treated with TNFis remain in remission at 3years
⏺️Week 14 levels significant in reducing
3
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84
📣📣📣📣📣💥💥💥💥
Truly transformational work by
@Dr_James_Lee
and
@TheCrick
team 👇
Macrophages driving IBD origin ; and perhaps also other autoimmune disorders
HUGE potential 👀
2
20
76
@drkeithsiau
@ExplosiveEnema2
@RCHTWeCare
@FPARCP
@BritSocGastro
@UKGastroDr
@parthaskar
@DrAsifQasim
@DrLKVaughan
@DrSteveTaylor
@AlisonGeorge10
@Dr_Done_
@Doctors_Vote
Thanks Kieth for clarifying. It is good to know you have robust processes for safe practice.
I do not however agree giving the analogy of other non medical endoscopists / clinical endoscopists who are often experienced GI/endoscopy nurses who develop into this role and are
3
6
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IF this information about GI bleeding rota is FACTUALLY CORRECT , it will be of serious concern in my opinion
@BritSocGastro
@JAG_Endoscopy
I am somewhat surprised as this hospital has excellent gastroenterologists & clinicians providing excellent GI care and also
I always suspected this was the case somewhere in the UK…
A Physician Associate doing GI bleed endoscopy‼️
As a Consultant, GI bleed endoscopy can be the most challenging work we do
I can categorically say this is unsafe & unacceptable from a patient safety PoV.
#Frightening
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241
651
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This is BIG and PRACTICE CHANGING for
#CD
care across the world
@ProfileCrohn
results presented
#ECCO24
Message : treat early and treat top down in CD
1
14
67
No second chance for monotherapy for anti TNF. The use of Aza a MUST if using a second anti TNF following secondary LOR with anti TNF monotherapy. RCT from the
#LaurentPB
and team .
2
26
65
@BritSocGastro
UK 🇬🇧 Ethiopia 🇪🇹 collaborative research grant kick off meet
👀 forward to progressing the ENABLE project on
#IBD
in 🇪🇹
🙏🏾
@BSGInternatnl
for the generous support
🔐: Belief that
#IBD
needs global solutions
#GlobalDisease
#GlobalSolutions
#Collaboration
9
4
63
🔥 hot of press in
@Gut_BMJ
First
@clarityibd
results
✳️ n= 6️⃣9️⃣3️⃣5️⃣
9️⃣2️⃣ 🇬🇧 🏥
🧐 impact of biologic class+/IMM on anti-SARS-CoV-2 seroconversion
🔎TNFi vs Vedo
🚨⬇️seroprevalence
🚨⬇️seroconversion
🚨⬇️anti-SARS-CoV-2 reactivity
🚨Further ⬇️with combo with AZA/MTX
3
26
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#WorldIBDDay2023
We are here at St Stephens shopping centre Hull
Already lot of interest and Q’s 🙋♀️ about
#IBD
2
8
59
Sharing with permission
📍Refugee ➡️self learning &up-skilled ➡️employed ➡️IBD after 6m➡️admission➡️lost job ➡️now onTx ➡️further up-skilling➡️back in employment ➡️ 💭 of starting own business
#PersonBehindTheInvusibleIllness
#ReasonWhyIDoWhatIDo
🙏🏾
#ReasonWhy
@IbdHull
exists
7
11
56
Join me in congratulating Dr Sree Subramanian ( working on him to join twitter !) from
@RoyalLpoolHosps
who is the recipient of the prestigious
@NIHR
-
@RCPLondon
research award for the phenomenal work in printing research in Mersey
#GI
research.
#risingstar
💫
11
6
54
Our 🇬🇧
@CrohnsColitisUK
@HelmsleyTrust
@BowelResearch
supported study on
#CD
Perianal Fistula
@GondomarIBD
has been initiated in 51 sites !! .
It is one the
@NIHRresearch
Associate PI scheme for early career researchers
If your 🏥 is not yet part of the study please do DM me
1
21
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#IBD
is 📈 a Global 🌎 problem
❗️Evolving epidemiology trends
❗️
#LLMIC
WILL be the new frontiers
⏯️🌎 Global problems need 🌎 Global solutions through 🧐 🔬
⏯️Research in
#IBD
should be Global 🌎
But is it really global 🌎 now ??
@LancetGastroHep
SR in collaboration
4
15
52
Away from 🌍 of
#IBD
🔥 of 📝
@Gut_BMJ
✳️ An attempt to 🆘 🚨 our role in mitigating climate change & protect our 🌏 ♻️
One of THE proudest collaborations 🙌👨👩👧👦🤝💪🏿
@anjan_dhar6
@DrBuHayee
@GreenEndoscopy
@BritSocGastro
@JAG_Endoscopy
@SusHealthcare
4
16
48
This 👇is incredible .
Wonder 💭 when we will ever reach this stage for
#IBD
🤔
Great hope to identify the causes of IBD by 🌎 research 🤞
Targeted depletion of TRBV9+ T cells as immunotherapy in a patient with ankylosing spondylitis | Nature Medicine
2
8
50
Sharing with patient permission
Patient on an RCT
Patient:
‘I got my life back’
‘I feel normal’
‘Is there any other research I can help with’ ? ‘
#IBD
#ResearchMatters
#WhyWeDoWhatWeDo
@IbdHull
2
6
48
🔥off the 🗞 .
Delighted to share 🇬🇧 study
#PROTECTASUC
@LancetGastroHep
🛑Dual challenge in
#IBD
#ASUC
: Need 🏥 Tx, High dose steroids
& 🦠:
🤔🧨 high dose steroids, immunosupp ,disease activity.
Mx and outcomes 👇- overall reassuring ❇️
4
24
48
@Y_ECCO_IBD
hosted
#ECCO
mentorship forum.
Future of
#IBD
in 🇪🇺 🇬🇧 in safe hands with this
#nextgen
Well done
@SamaanMark
,
@rjcdart
@nuru_noor1
for the brilliant organisation
3
11
48
Finally got to meet some one who I respect a lot - the master clinician and researcher
@fgomollon
#Inspiration
#ECCO24
5
3
48
This is an important moment for ECCO - truly global 🌎 organisation
Gill Watermeyer
@ibd_africa
with
#ECCO2023
lecture
Sobering data of challenges 🥲
Really concerning re: brain drain - we should & can do better
@BritSocGastro
3
15
45
Absolutely fascinating data from GEM Project on environmental influences in
#CD
@guthealthmd
Early exposure to pets and impact of microbiome and barrier function 🤔
We all need to get a 🐶 🐕 !!
5
14
45
Delighted to have completed the
#VirtualRunforGuts
. Ok snail 🐌 pace but took in the local scenery on the way. 🙏 to all those who dipped into their pockets to support this small contribution led by
@GastroMJB
. Thank you
@CrohnsColitisUK
and
@GutsCharityUK
for all what you do
7
5
44
Alternate day versus daily oral iron for treatment of iron deficiency anemia: a randomized controlled trial | Scientific Reports
Another nail in the ⚰️for the overuse of oral iron in IDA
Nice study from 🇮🇳 by
@basheeraneesh
@UKGastroDr
0
15
44
Hi
@British_Airways
Perhaps you should train your crew on equality , diversity so that covert racist behaviour is not experienced by your customers. Not asking for apology but please attempt to change end
8
3
43
Perhaps THE best talk so far of
#ECCO2023
❓: What makes a good IBD physician and a good IBD surgeon
@JeanFredericCo1
and AndreD’ Houre
1
11
43
@charlie_lees
#DDW2023
First data from
@predicct
study from 🇬🇧
Meat 🥩 intake seems to increase risk of flares
But no impact with Fibre and PUFAs and UPFs 🤔
2
7
42
Massive 🙏 to our
@HullHospitals
CEO Chris Long and chief nurse
@Bgearyyork
for inaugurating our new immunomodulatory infusion centre (IMIC) for
@IbdHull
. 🙏 for spending time time with our patient panel reps and
#IBD
team.🙏for offer to support us in our vision
#excellence
1
3
42
The integrated
#IBD
team
@HullHospitals
10 years old and now reaping the benefits of the model ▶️ better patient outcomes 👀data soon .
🙏our research active patients
🙏the excellent leadership from
@EmmaIBDhull
&
@salhullibd
🙏
@IbdHull
team.
9
4
41
#worldibdday2021
.
We
@IbdHull
hope we can continue to deliver the best possible care to our
#IBD
pts via
#integratedcare
Massive 🙏 to our
#IBD
patients for their
❇️ resilience & ❇️patience through a challenging period
and for
❇️ for supporting our research.
1/2
2
8
41
International Fistula Consortium meeting
@DDWMeeting
#DDW2023
Trying to tackle this challenging area of
#CD
#UnmetNeed
👀 out for outputs from this multidisciplinary collaboration
1
6
41
IBD Investigators Day
For 🇬🇧
#IBD
#HCPs
interested in research
Please do register 👇
Led by
@NickPowellLab
@DrNickKennedy
@ResearchBsg
@BSGTrainees
@BSGNurses
0
15
40
🙏🏾
@LancetGastroHep
for shining a 💡 on practical approaches on reducing disparities in
#IBD
- this commentary focussing on training.
Professional orgs such as
#ECCO
@AmerGastroAssn
@BritSocGastro
@AmCollegeGastro
&other professional societies+ all IBD HCPs have a role to play.
New Comment -
@DrAnuraagJ
et al - Reducing disparities in training in inflammatory bowel disease
@ibdseb
#IBD
#gitwitter
5
16
45
1
8
37
Got to meet a genuine nice person , a future # IBD 🌟 and of course
#SoMe
legend
@JosephHabibi_MD
#ECCO24
#IBDWithoutBorders
1
4
40
🎉1️⃣2️⃣ abstracts from or involving
@IbdHull
accepted for oral plenary/digital oral or poster presentation at
#ECCO2023
🙏🏾to our
#IBD
patients and team
Most proud of is a poster 👇led by a 1st yr resident
@khin_phwe_nu
(m& a new
#IBD
nurse
#nextgen
#integratedibdcare
#research
2
6
38
Over 1️⃣2️⃣5️⃣
#IBD
patients participating the
@CrohnsColitisUK
@CrohnsColitisR
patient inv. in 🔬🧐 day -🙏🏾
Highlighted
@GondomarIBD
@IBDResponse
#ADDapt
by
@ProfWhelan
@IBD_BioResource
etc
🙏🏾 for inviting to share some 💭
@IbdHull
@HullHospitals
@ResearchBsg
@southasianIBD
2
4
39
Just out 🔥
SARS-COV-2 💉 in
#IBD
:
@BritSocGastro
IBD section & Clinical Research Group guidelines 👇
Led by
@NickPowellLab
&
@charlie_lees
@HullHospitals
2
15
39
Massive thanks 🙏🏼
It was an absolute honour to return to my alma mater and to see so many familiar faces and some new faces
Humbled and stimulated by the quality and sheer volume of work being done
@gi_pgi
Highlights many to mention including seeing the person who taught me
3
3
38
Prof Miles Parks re-informing the role of thiopurines in UC
#BSGLIVE22
- some intriguing 🧐 thoughts regarding real world practice
2
2
37
Excellent
@IBD_BioResource
group meeting led by Prof Miles Parks .F2F 👍.Exciting projects on the horizon.Great discussions on practical delivery of 🇬🇧
#IBD
projects
@charlie_lees
@DrNickKennedy
.
Great vision with 🔐 focus areas till 2030 from
@anderson_carl
Then the 🍻
3
4
36
#ECCO2021
@ryanungaro
showing what we suspected before
Mesalazine after all NOT associated with increased risk of severe
#COVID19
⏺Evolution of data
⏺Limitation of registry studies with convenience sampling
1
10
36
#IBD
🧐 🔬 in 🇬🇧 is in a great place .
Really 👀 forward to
📍 hearing the successful studies such as
@ProfileCrohn
@IBDBOOST
@AwareIbd
delivered by 🇬🇧
#IBD
community
📍 re-energise / turbocharge on
@IBDResponse
@GondomarIBD
@OCEaN_Trial
@MarvelTrial
@IBD_BioResource
📍
The IBD research landscape in the UK is rich and deep.
Many practice changing studies in various stages of development and dissemination.
Promises to be an invigorating
@BritSocGastro
day tomorrow in Exeter.
3
8
49
1
7
36
I don’t usually comment on political matters but this is worth retweet 👉Respect standing up for the right think
👉How many people in positions of influence even in professional organisations are prepared to back a right message 🤔
I have informed the BBC that I won’t be appearing on MOTD tomorrow night.
32K
36K
430K
3
4
36
Tough life ☺️
After a busy (but enjoyable ) day learning
#IBUS
chill time with some of the faculty and colleagues
🙏🏼
@novakkerri
@guthealthmd
for the hospitality
2
5
35
@DCharabaty
@MondayNightIBD
16y/oM seen w recurrent mouth ulcers+Lip swelling x3 yrs ->Bullied at school.
Bx: granulomatous inflam. Occ loose BM, no blood, no abdo pain. Growth-Normal.
Hb 10, FCP 212.
CLN: few aphthous ulcers colon +TI; Bx: chronic inflam,no granulomas. MRE -normal.
What Rx do you start?
Elimination diets
68
Topical/ 💉steroids
62
Oral steroids,then aza
79
Biologics
111
17
16
36
@DrChrisLamb
Worthy recipient of the Francis Avery Jones Award
Key messages in his journey so far as an
#IBD
researcher
#BSGLIVE2023
1
5
36
DOP44 Tofacitinib versus corticosteroids for induction of remission in moderately active ulcerative colitis (ORCHID):
This study from 🇮🇳 is interesting (as well as sobering)
steroids = tofacitinib in induction of remission & response
3
14
36
Ustekinumab for type 1 diabetes in adolescents: a multicenter, double-blind, randomized phase 2 trial | Nature Medicine
🤔
Thoughts
@charlie_lees
?
5
2
35
New MOA of
@my_ueg
#UEGWeek2023
@SeverineVermei1
Obefazimod - a miR 124 based small molecule in
#UC
. Originally developed for an infection🤔
Relatively refractory population
2 year data looks good 👇
0
7
34
Dose optimisation for
#Vedo
in primary NR @ week 6 with high clearance doesn’t improve response rates
Clinically relevant results from ENTERPRET Trial
🔑 receptor occupancy ?
@AndresYarur
#DDW2022
1
12
34
Bispecific antibodies as a strategy for breaking therapeutic sealing in
#IBD
@Iris_Dotan
- brilliant futuristic lecture on an approach learning from oncology field .
Side effects will be the concern . Is this a runner ? 🤔
#ECCC2023
2
7
32
One of the most enjoyable and rewarding aspects when travelling for
#IBD
#MedEd
is meeting residents
Here
@YashodaHospital
discussing integrating research into daily clinical care in
#IBD
Hope I can inspire the residents.
I am truly inspired by incredible quality in India
2
1
33
Delighted to share our paper in
@APandT
from
@ElevateAsuc
study group accelerated IFX induction in steroid refractory acute severe colitis.
@ElevateAsuc
prospective study with clinical,pharmacokinetic ,endoscopic and translational work packages on way
3
17
32
👇
This is exactly how it should be done 👏👏👏
#ResearchForPatients
#ResearchByPatients
Something we are also incorporating in all our
@IbdHull
studies
@CrohnsColitisR
@CrohnsColitisUK
Well done
@UmaMahadevanIBD
&
@PIANOIBD
team
Are you a
@PIANOIBD
patient and have a study idea? What data have we been collecting from you that would be an interesting question? Let us know on the FAQ page. just click "propose a study ?"
@MLongMD
@UmaMahadevanIBD
@ChronicallyJess
@IBDMoms
4
9
27
2
6
32
Pregnancy outcome data on patients exposed to Ozanimod across various indications
0
10
32
The New classification of pCD is a vital step progressing research in personal fistula in CD . Suggest all
#IBD
units use this .
The original paper
An analysis of the use of the
#TOPCLASS
classification 👇
#TOpCLASS
classification highlights the dynamic nature of perianal fistulizing
#CD
over time, however, our ability to predict transitions between classes remains limited and requires prospective assessment.
@MattSchro314
@P_DeepakIBDMD
@ibdseb
2
16
30
0
12
32
This 💯
In the clinical trials space for
#IBD
therapeutics , significant under representation & underreporting exists as we recently reported in
@LancetGastroHep
…👇
BUT : I do feel we are getting better
We need to do more
5 Keys 🔑 steps IMHO
Inflammatory Bowel Disease does not discriminate.
Tens of millions of people are affected across the world.
But they cannot expect the same care, the same access to therapies and monitoring tools.
Within countries with the same rules, the same drugs and the same healthcare
2
24
79
1
6
31
#DDW2023
@JoanaTo62523004
summarising the current studies on pre-clinical prediction of
#IBD
Included
#GEM
study to which we
@IbdHull
contributed
And the excellent
#PREDICct
study led by
@JeanFredericCo1
#Glycans
also of interest
Can we integrate the markers ?🤔
3
8
31
We are getting closer to understanding different
#IBD
phenotypes .
This 👇is a must ready from the incredible
@WeersmaLab
@BourgonjeArno
Mucosal host-microbe interactions associate with clinical phenotypes in
#IBD
|
0
7
31
Start of the
#IBUS
course in Toronto hosted by
@novakkerri
&
@guthealthmd
Keen to bring this back to patients
@IbdHull
Thank you for the opportunity
0
3
30
👇This is part of
#ECCO
commitment to global 🌎 education& research 🧐 🔬
Looking forward to supporting
@AlaaEl_Hussuna
in this imp work
If you are an
#IBD
HCP in a LMIC country& passionate about progressing
#IBD
care across the 🌍 please do consider applying
#Equity
#IBD
Invitation
Dear
#gastroenterologists
,
#surgeons
,
#healthcare
professionals and
#researchers
:
On the behalf of the
#ECCO
(EuropeanCrohn’s &Colitis Organization), I would like to invite you to join a consensus study about the management of inflammatory bow…
10
41
56
2
11
30
Appropriate comment from a legend honouring another legend
#respect
@JeanFredericCo1
Emotion appears in Jean Frederick face as he is recognized as a great researcher, mentor and leader of
#IBD
family all over the world. 👍👍👍👏👏👏
#DDW2024
3
6
86
0
1
30
Humbled to to be involved
@southasianIBD
- a unique
#IBD
Patient-HCP initiative addressing the unmet needs in a new frontier of
#IBD
Yes we need to
⏺
#ShatterStigmas
⏺
#BeeakTheSilence
⏺
#ProvideEquity
⏺
#BuildPartneships
⏺
#GlobalResearch
#GameOverIBD
#WorldIBDDay2022
Happy
#WorldIBDDay
from the SAIA/
@ibdesis
team!
Today we join hands as patient advocates and healthcare providers to encourage our fellow
#IBD
family around the world to
#BreakTheSilence
& say
#GameOverIBD
!
Teamwork makes the dream work! Join us today in breaking the silence!
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