Michael Torres
@Mykalt45
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PhD in Cancer Bio @utswmedcenter . Entrepreneur. CEO @CrossBridgeBio . @ReCodeTX Co-founder & Former VP R&D. EIR @TMCInnovation . @NIH_OITE UGSP scholar. ArtanBio.
Houston, TX
Joined April 2011
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Thank you
@bradloncar
for coming by. Always a pleasure seeing you. I look forward to the next visit. Lots happening!
Bright Minds:
@Mykalt45
talks about TMC Innovation, the biotech ecosystem in Houston, and founding companies.
Full video:
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Some know my story, but after my parents divorced when I was 7 (both my parents are great) my mom did all she could to raise us. That meant growing up in HUD homes, using WIC and food stamps. The world I’m in now still feels so foreign to me. I still have much to learn.
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Talked to a family office last night. “We’ll write a $5M get to know you check, but we want to start doing $20M-$30M sized bets.” They said they’re tired of investing in funds because while having average performance is fine, they want to make a direct impact and bigger returns.
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And to cap off my work week, we closed on our house in Houston!
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Just installed a WiFi connected outdoor camera to watch an American Robin nest her eggs along our fence. Our girls (6 & 8) are thrilled.
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Time to rotate out of tech to biotech! We’re saving lives here people!
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My wife graduated with her Master’s in Education today. Super proud!
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Maybe I’ve missed it, but is there a good resource on building a biotech (therapeutics-focused) budget? This is one area that I personally need to optimize better. Any advice from VCs who often look at Seed and Series A budgets would be helpful!
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In the spirit of
#DeSci
, we just got data from our CRO that shows our AAV9-based gene therapy for aging has activity in vitro! Will be posting the report on GitHub shortly. We hope to be working with CDMOs soon to scale up production. Appreciate the support and backing of
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Funding secured…for our lead program. Official PR coming soon, but I had to share. Top score to boot! Thankful for the team I’ve been able to assemble! Go,
@crossbridgebio
! Thanks,
@CPRITTexas
, for your support!
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I officially resigned from UTSW this week. Happy to move full time 2 the company we founded. Also giving a talk at CF con in Portugal. Busy!
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Celebrating 18 years of marriage today! I’m proud of what we’ve built so far! Life-hack: Find someone great to do life with and it’ll make your life so much better!
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Very thankful for today. Ari is celebrating 1 year
#seizurefree
on
#keppra
. Love this girl so much.
#twitter
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A friend says all kidney companies with approved drugs get bought… $ARDX.
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Wow…Longevity is blowing up! Happy to be supporting
@vita_dao
alongside folks like
@scienceman2023
@aschwartzphd
@DToddWhite
@alxdobrin
@benjileibo
@GolatoTyler
@timrpeterson
and so many others. When big banks take notice, you know you’re onto something.
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Daughter’s MRI using our health insurance: $1300. Daughter’s MRI without insurance (cash price): $450. Crazy.
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Saturday night grant writing. $3M on the line, so worth it to put the hours in! We’re excited to have been asked to move on to the next stage! Good thing I have an awesome team driving this home! More to share soon, but I’m absolutely grateful to be able to be where we are!
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We’re doomed. This is in my Facebook stream as proof this is overhyped and not a real threat. Really wish government would step up and better educate.
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Pro tip: Translating academic research into drugs is hard. Doing it with a team that’s not equipped, hasn’t done it before, and led by people who “know enough to be dangerous” is a bad recipe. The funds and startups that address this fully will be better positioned to succeed.
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Feeling those 18-years of marriage vibes! Great dinner in H-Town!
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Not a bad place to be giving a talk today. Thanks
@vita_dao
and
@MaxUnfried
for the invitation.
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Past year: started a project, patented IP, co-founded company, licensed said IP + portfolio, got funds, and now strategizing on financing..
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Not as great of a pic as I wanted, but it was great to have
@bradloncar
and
@cngarabedian
here in Texas! Lots of exciting things happening! (Time to upgrade to iPhone 15 Pro!)
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Celebrating 12 years of marriage. Nice family dinner. (@ Gloria’s Latin Cuisine in Irving, TX)
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As someone who has worked on this, I’m bullish on the ability of these LNPs to deliver cargo to the appropriate cells.
1/
@intelliatx
&
@ReCodeTx
- which uses tissue-specific delivery to power
#mRNA
& gene correction therapeutics announced today a joint strategic collaboration aimed to develop novel genomic medicines for the treatment of
#CysticFibrosis
. $NTLA
#GeneEditing
#CRISPR
#BioTech
$XBI
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Very cool. I’ve been nominated as one of the
@CF_Foundation
@CFF_NETX
#Dallas
’ Finest Under 40! Hope to be able to further
#cfawareness
!
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Been a great journey from an idea in the lab. Some of you have watched this story since I was a postdoc yammering about an idea to raising our initial funds, to this. Feel proud to be a part of this team and to have great backing.
i learned many new things from this interview: cystic fibrosis' "sister disease," tRNA, and how the small team is planning under pandemic
Coupling mRNA with tRNA and new delivery tech, MPM and OrbiMed help birth new $80M biotech into a slowed down world-
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Two years into my postdoc and have a VC-backed company started and lots of hope for a promising tech for patients. Now it's paper time.
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Those Friday news drops…LOL! ;)
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The PCSK9 $VERV debate is an interesting one. Gets back to target and proving your platform. It’s odd to me because investors want low risk, validated targets, yet targets like Her2, CD19, etc are “bad” targets, yet novel is too risky, but the commercial risk can be enormous if
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Wow. Can't believe Clinton advisor on Fox News Sunday said people no longer have financial problems paying for health care due to ACA.
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#NewProfilePic
Even though it ended up being a more stressful trip than I wanted, I did manage to get a great pic with my wife.
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Those who know me know how truly passionate I am about developing transformative therapies. Truly an honor to have the support and backing of all involved to make this a reality.
Today we are spotlighting our VP of R&D, Board Member and Co-Founder, Michael Torres, Ph.D. We are thankful for the experience he brings to managing our company's Dallas site where we are advancing our
#cysticfibrosis
program and leading new discovery efforts.
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This is going to be a crazy week. Hope to lock down the syndicate for my Seed round now that we have the final term sheet in hand. Go
@CrossBridgeBio
!
On another front, we got some really nice data for ArtanBio, my
@vita_dao
,
@Molecule_dao
, and
@OrangeDAOxyz
IPT-NFT, $VitaRNA.
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With the
@bradloncar
pic, DeSci and TradSci collide! Lol.
Just in: We will have a special guest for our "State of DeSci" Space tomorrow.
Michael Torres,
@Mykalt45
, Chief Scientific Officer at $VitaRNA, will join us LIVE to share his insider-insights on the latest breakthroughs.
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I hope 2024 is the year I can do more direct investing in startups. What better way to make a difference than by directly supporting entrepreneurs and teams working to create medicines that could impact so many. Why get your name on a building when you can point to a therapy?!
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It’s nice when a BD guy with close to $10B in transactions thinks my strategy is spot on. Makes me feel like I really have a shot to be a successful entrepreneur that brings effective drugs to patients who have none. Proud of the work being done at
@ReCodeTX
.
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It’s an interesting paradigm where you can be sitting on good science, but to move it forward, it largely hinges on how good you are at telling the story. If you don’t nail that, it’s going to be mighty difficult to raise from VCs. Thoughts?!
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I have a brother who deals w/PTSD and a TBI after serving in Iraq. The sacrifices for our country can be great. Thanks to all who've served.
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Wife and I are celebrating 11 years of marriage today. Sweet room at
@ZaZaDallas
and dinner
@risesouffle
. Going to be a good night!
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Send good vibes my way. I’m having a meeting today with a group that are doing some really cool things. I’m fortunate to be able to take my time, but I’ve prepped hard for this one.
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Patio dinner. Lots of tequila. Kids at my brother’s house. We good!
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“Post”-pandemic family pic! Getting those covid-19 negative tests at least! First time at Atlantis in the Bahamas. Was awesome!
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Pretty excited. Have confirmed visits by $ABBV, $VRTX, and a few others to my poster at
#NACFC2016
. Looking forward to sharing.
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Watching Sunday news and seeing the “months to vaccine” timelines. We don’t have a great track record with developing vaccines for viruses. Just amazed how much it seems we’re expecting that to be a magic bullet coming ASAP.
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Lung SORT LNPs enable precise homology-directed repair mediated CRISPR/Cas genome correction in cystic fibrosis models | Nature Communications. Excited to have played a part in this.
@CF_Foundation
#pathtoacure
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@adam_thiesen
Agree. I’ve been saying this every chance I get: While your name on a building is great, imagine being able to point to a drug you supported that makes a difference in many people’s lives. Now that’s impact.
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Proud Dad moment! Our girls got their STAAR scores back! Master’s in all subjects and my oldest scored in the 99th and 100th percentile for math and reading!
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Posted the link to the CRO report here. I also provided additional commentary. Keeping the
#DeSci
train going!
@Molecule_dao
@bioprotocol
@vita_dao
In the spirit of
#DeSci
, we just got data from our CRO that shows our AAV9-based gene therapy for aging has activity in vitro! Will be posting the report on GitHub shortly. We hope to be working with CDMOs soon to scale up production. Appreciate the support and backing of
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Every young venture group should have someone here at Zuzalu. Great vibe and actually great science being discussed and shared.
@vita_dao
@athena_DAO_
@Molecule_dao
Even at
@zachweinberg
would find it useful! :)
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Some of you guys know, but we’re weaning my oldest daughter off of
#keppra
. She’s been seizure free for 3 years, so we will see what happens. A little scary for us as parents. She did great on the medicine and no issues on the meds. She’s actually in GT and top of her class.
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Anyone interested in getting paid to build companies in Houston?! If so, slide into my DMs!
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I’m going to get COVID-19 waiting in line to buy antigen tests at CVS.
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I’m in Mexico celebrating 15 years of marriage with my wife at an all inclusive resort, do not hold anything I say against me! Cheers everyone!
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Man, they’re trying to keep Chinese made drugs out the US, how do you think they’re going to be with Chinese-only clinical data. Lol.
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The ORR of ADC2 in patients treated with similar payloads was 5.3%. And the ORR of ADC2 in those treated with different payloads was as high as 22.6% (P = .180). (Lots of good info to unpack)
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My 7 year old daughter’s painting. She drew the frog by hand and then painted it! She’s so creative like her dad!
#mylittlelove
#twitter
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Wowza, $VERV. We’ll see how it plays out, but I do believe the sentiment for editing when there are viable alternatives is going to be a challenge. Time will tell if non-rare is viable.
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Bought $MDGL at $247 this morning and just sold at $301. Not bad as a day trade. Takes me back to the good old days! (Plenty of “loosing” trades in my book!)
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Glad to be back home in my favorite time zone and with my crew.
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I have a simple goal. To make select investors a lot of money so they’ll invest in whatever I like, carte blanche. Alternatively, if I ever get a nice exit from ReCode, I’ll angel invest myself and make it easier for others in the future.
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I had a really great meeting with my teammates today. We’re building something unique. If there’s any seed investors interested in the ADC space, let me know. I’ve got half the round committed and would love to have a solid lead VC step up.
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Building biotech companies is fun, especially when you can do it with a good team, good science, and a real chance to provide a therapy for people who have none.
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My 2nd grader just discovered she can write the authors of her favorite books to ask questions. Not surprisingly, most authors write back and are delighted. She has consistently said she wants to be an author and illustrator. Trying to encourage this as much as we can!
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@Molecule_dao
and groups like
@vita_dao
and
@athena_DAO_
are leading the way. Worth a look for sure! $VITA!
Been reading about biotech, thinking about how to use crypto to accelerate research funding there.
Keep building!
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